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Organic bicyclic compounds that consist of two fused furan rings; furan rings consist of a five-membered ring with four carbon atoms, one oxygen atom, and two double bonds.
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Doxifluridine (CAS 3094-09-5) is a small-molecule prodrug that modulates thymidine phosphorylase activity In PC9-DPE2 cell models doxifluridine demonstrates an IC50 of 0 62 M indicating potent activation of thymidine phosphorylase-dependent processes This compound is widely utilized in biomedical research to investigate nucleoside analog metabolism enzyme activation pathways and their implications in cancer cell sensitivity and resistance mechanisms
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