Imidazopyridines
Medchemexpress LLC Diethyl pyridine-2,4-dicarboxylate | 41438-38-4 | MFCD00152168 | 99.8% | 223.23 g/mol | C11H13NO4 | 100 MG
Diethyl pyridine-2,4-dicarboxylate (CAS 41438-38-4) is a small-molecule proinhibitor of prolyl 4-hydroxylase used in biochemical research to inhibit prolyl hydroxylation and procollagen processing. It is supplied as an off-white to light-yellow solid with high purity suitable for laboratory studies.
- Inhibits prolyl hydroxylation and procollagen processing in biological assays.
- High purity for reproducible experimental results.
- Solid form allows flexible formulation and storage.
- Suitable for biochemical and cellular research applications.
- Characterized by a defined molecular formula and molecular weight for identification.
Medchemexpress LLC NOT Receptor Modulator 1 | 1015231-98-7 | 362.85 | 50 MG
NOT Receptor Modulator 1 is a nuclear receptor Nurr-1/NOT modulator. It was extracted from patent WO 2008034974 A1, Example 39 in table1.
- Purity: 98.61%
- Molecular weight: 362.85
- Chemical formula: C22H19ClN2O
- Appearance: White to off-white solid
- CAS number: 1015231-98-7
- Storage conditions: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO: 125 mg/mL (344.49 mM)
- Target: Nuclear receptor NOT (EC50 = 218 nM in CHO cells)
Medchemexpress LLC 3-cl-pyridine-amide-acrylaldehyde-piperazine | 99.3% | 294.74 | 25 MG
This product is a synthetic intermediate of LO-4-25 (HY-176067), an androgen receptor (AR) DNA binding domain ligand. LO-4-25 robustly degrades both AR and AR-V7 in 22Rv1 cells.
- Synthetic intermediate for LO-4-25.
- Androgen receptor (AR) DNA binding domain ligand precursor.
- Facilitates robust degradation of AR and AR-V7 in 22Rv1 cells.
Medchemexpress LLC (E)-5-((8-methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydrazid | 2469975-55-9 | 98.6% | C28H25N5O2S | 10MG
Nur77 modulator 1 is a small-molecule research compound that modulates the nuclear receptor Nur77 (NR4A1), promotes Nur77-dependent endoplasmic reticulum stress and autophagy, and can induce apoptosis; it has been applied in hepatoma models and shows a measured binding affinity to Nur77.
- Chemical formula C28H25N5O2S.
- Molecular weight 495.60 g·mol⁻¹.
- Purity 98.6%.
- CAS number 2469975-55-9.
- Reported KD against Nur77 3.58 μM.
- Available in mg-scale quantities for research use.