Imidazopyridines
Selleck Chemical LLC IRAK inhibitor 6 S2039-2mg
IRAK inhibitor 6 is a selective Interleukin-1 receptor-associated kinase 4(IRAK4) inhibitor with IC50 of 0 16 M
Medchemexpress LLC HY-12425 5mg Medchemexpress, DGAT1-IN-1 CAS:1449779-49-0 Purity:>98%
Medchemexpress, HY-12425 5mg DGAT1-IN-1 CAS:1449779-49-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Elsulfavirine (R-1206) | 868046-19-9 | 99.9% | 629.28 | 100 MG
Elsulfavirine (R-1206) | 868046-19-9 | 99.9% | 629.28 | 100 MG
Medchemexpress LLC Az084 | 929300-19-6 | 99.7% | 10 MG
AZ084 is a potent, selective, orally active CCR8 allosteric antagonist provided for preclinical research. The compound is characterized with manufacturer-reported purity, molecular data, solubility protocols for in vitro and in vivo use, and recommended storage conditions to support pharmacology and immunology studies.
- Potent CCR8 allosteric antagonist with reported Ki ≈ 0.9 nM.
- High purity reported at 99.65%.
- Molecular weight 434.57 g/mol; formula C26H34N4O2.
- Soluble in DMSO (250 mg/mL) and formulatable for in vivo dosing protocols.
- Appearance: light yellow to yellow solid.
- Storage recommendations: powder at -20°C (long term) and in solvent at -80°C for best stability.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Odoroside A | 12738-19-1 | 5 MG
Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. It exhibits anticancer activity by inducing apoptosis and cell cycle arrest through the ROS/p53 signaling pathway, which leads to tumor cell death. This compound has a molecular weight of 518.68 and a molecular formula of C30H46O7, appearing as a white to off-white solid. It is classified under steroids and is initially sourced from plants in the Apocynaceae family.
- High purity: 99.73%
- Induces apoptosis and cell cycle arrest
- Targets the ROS/p53 signaling pathway
- Active against various cancer cell lines including A549, HepG2, and WI-38
- Soluble in DMSO (100 mg/mL)
- White to off-white solid appearance
- Classified as a steroid
Medchemexpress LLC Estrogen receptor modulator 1 | 63676-22-2 | 99.91% | 242.29 | 500 MG
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
- Orally active and selective estrogen receptor modulator (SERM).
- Induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
- Inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation at 100 nM for 10 days.
- Significantly inhibits the growth of MCF-7:5C cells and induces apoptosis at 100 nM for 9 days.
- Appearance: Solid, White to off-white.
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: Powder at -20°C for 3 years; In solvent at -80°C for 6 months, or -20°C for 1 month.
Medchemexpress LLC Samatasvir | 1312547-19-5 | 99.4% | 885.06 | 5 MG
Samatasvir is a potent, orally active NS5A inhibitor of HCV replication. It is effective and selective against infectious HCV and replicons, with EC50s ranging from 2 to 24 pM in genotype 1 through 5 replicons.
- Potent, orally active NS5A inhibitor of HCV replication.
- Effective and selective against infectious HCV and replicons.
- Retains full activity in the presence of HIV and hepatitis B virus (HBV) antivirals.
- Not cross-resistant with HCV protease, nucleotide, and nonnucleoside polymerase inhibitor classes.
![Medchemexpress LLC Pentanedioic acid, 1-[2-[[[8-[(2,6-dimethylphenyl)methyl]amino]...ethyl] ester | 1228559-81-6 | 99.7% | 480.56 g/mol | C26H32N4O5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221581.png-250.jpg)
Medchemexpress LLC Pentanedioic acid, 1-[2-[[[8-[(2,6-dimethylphenyl)methyl]amino]...ethyl] ester | 1228559-81-6 | 99.7% | 480.56 g/mol | C26H32N4O5 | 5 MG
Linaprazan glurate is an orally active ethyl-ester prodrug of linaprazan that acts as a potassium-competitive acid blocker. It is supplied as a white to off-white solid for research and pharmacological studies on gastric acid secretion, ADME, and therapeutic evaluation.
- Potent potassium-competitive acid blocker.
- Orally active prodrug of linaprazan.
- High purity (~99.7%).
- White to off-white solid suitable for analytical and in vivo research.
- Available in small packaged amounts for screening and dose-finding studies.
- Molecular formula C26H32N4O5; molecular weight 480.56 g/mol.
Medchemexpress LLC Linaprazan glurate | 1228559-81-6 | 99.7% | C26H32N4O5 | 10MG
Linaprazan glurate is a small-molecule research compound that acts as a potassium-competitive acid blocker and is used in preclinical studies of gastric acid secretion and proton pump-related mechanisms. It is supplied as a high-purity solid for analytical, synthetic, and medicinal chemistry applications.
Medchemexpress LLC Az084 | 929300-19-6 | 99.7% | 5 MG
AZ084 is a selective, orally active CCR8 allosteric antagonist for research use. It demonstrates sub-nanomolar potency and is supplied as a high-purity solid suitable for in vitro and in vivo pharmacology studies. Solubility and storage guidance are provided to support experimental formulation and handling.
- Selective CCR8 allosteric antagonist with Ki ≈ 0.9 nM.
- High purity suitable for cellular and pharmacological assays.
- Supplied as a milligram-scale solid for in vitro and in vivo use.
- Highly soluble in DMSO; formulation examples provided for dosing.
- Recommended storage conditions for powder and solutions to preserve stability.
- Intended as a research tool for immunology and inflammation studies.
Medchemexpress LLC Bi-1622 | 2681392-19-6 | 99.0% | 508.53 g/mol | C26H24N10O2 | 10 MG
BI-1622 is an orally active, potent, and highly selective inhibitor of the HER2 (ERBB2) kinase, developed for preclinical research. It has reported biochemical potency (IC50) of 7 nM, shows greater than 25-fold selectivity over EGFR, and has demonstrated efficacy in HER2-driven xenograft models.
Medchemexpress LLC CXCR7 modulator 1 10mg | 2231812-31-8 | 10MG
CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator with a Ki of 9 nM[1
![Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000393984.png-250.jpg)
Medchemexpress LLC 4-Oxazolecarboxamide, N-[6-[(2-methoxyethyl)methylamino]-3-pyridinyl]-2-phenyl-5-(trifluorom | 939375-07-2 | 99.9% | 420.39 | 100 MG
DGAT1-IN-3 is a potent, selective, and orally bioavailable inhibitor of DGAT-1. It can be used for research on obesity, dyslipidemia, and metabolic syndrome.
- Potent, selective, and orally bioavailable inhibitor of DGAT-1.
- Inhibits human DGAT-1 with an IC50 of 38 nM.
- Inhibits rat DGAT-1 with an IC50 of 120 nM.
- Supports research into obesity.
- Supports research into dyslipidemia.
- Supports research into metabolic syndrome.
- Reduces cumulative body weight gain in DIO rats.
- Reduces weight gain and plasma triglycerides.
- Improves lipid profiles.