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Filtered Search Results
![eMolecules 159730-12-8 | 6-Methyltryptamine hydrochloride | Chem-Impex | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502178210.JPG-250.jpg)
eMolecules 159730-12-8 | 6-Methyltryptamine hydrochloride | Chem-Impex | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382
6-Methyltryptamine hydrochloride | Chem-Impex | 159730-12-8 | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382
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Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g/mol | C21H19F4N5O3 | 5 MG
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A potent, selective small-molecule inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) with a reported IC50 of 11.5 nM. The compound has molecular formula C21H19F4N5O3, molecular weight 465.40 g/mol, and is supplied as a white to off-white solid for use in biochemical and cellular research.
- Potent PARP-2 inhibition (IC50 11.5 nM).
- High chemical purity (99.6%).
- Molecular formula C21H19F4N5O3 and molecular weight 465.40 g/mol for easy reference.
- Supplied as a solid suitable for handling and storage.
- Manufacturer documentation available: data sheet, COA, and SDS for characterization.
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eMolecules 116751-24-7 | 3-Hydroxy-2,4,5-trifluorobenzoic acid | Ambeed | MFCD00800378 | 192.093 | C7H3F3O3 | 98.000 | OC(=O)c1cc(F)c(F)c(O)c1F | 1g | 632809333
3-Hydroxy-2,4,5-trifluorobenzoic acid | Ambeed | 116751-24-7 | MFCD00800378 | 192.093 | C7H3F3O3 | 98.000 | OC(=O)c1cc(F)c(F)c(O)c1F | 1g | 632809333
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Medchemexpress LLC PI3Kα-IN-4 | 2322293-83-2 | 99.8% | C25H23ClFN5O5S | 10MG
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PI3Kα-IN-4 is a selective, orally active small-molecule inhibitor of PI3Kα with potent biochemical activity (IC50 1.8 nM) and demonstrated antitumor efficacy in vivo. Supplied as an off-white to yellow solid with high purity, it is formulated for research use with characterized solubility and storage profiles suitable for in vitro and in vivo studies.
- Selective PI3Kα inhibition with potent biochemical potency (IC50 1.8 nM).
- Demonstrated cellular activity and antitumor efficacy in preclinical models.
- High chemical purity suitable for research applications.
- Good solubility in DMSO for preparation of concentrated stock solutions.
- Stable solid form with defined refrigerated and frozen storage recommendations.
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eMolecules AstaTech / (S)-N-((3-(3-FLUORO-4-(PIPERAZIN-1-YL)PHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)ACETAMIDE / 0.1g / 696743114 / D83829 / 95.000 / 154590-66-6 / MFCD18089805 / 336.367 / C16H21FN4O3
AstaTech / (S)-N-((3-(3-FLUORO-4-(PIPERAZIN-1-YL)PHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)ACETAMIDE / 0.1g / 696743114 / D83829 / 95.000 / 154590-66-6 / MFCD18089805 / 336.367 / C16H21FN4O3
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Medchemexpress LLC Fkbp12 protac rc32 | 2375555-66-9 | 97.0% | 50 MG
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FKBP12 PROTAC RC32 is a potent FKBP12 degrader based on PROTAC technology. This degrader combines Rapamycin and a Cereblon E3 ubiquitin ligase ligand, Pomalidomide. It achieves approximately 50% protein degradation (DC50) of FKBP12 at 0.3 nM in Jurkat cells within 12 hours. In vivo, it effectively degrades FKBP12 in most organs of treated mice, Bama pigs, and rhesus monkeys, with oral administration also showing significant degradation in mice.
- Potent FKBP12 degrader based on PROTAC technology
- Composed of Rapamycin and a Cereblon E3 ubiquitin ligase ligand
- Achieves 50% protein degradation (DC50) of approximately 0.3 nM in Jurkat cells within 12 hours
- Degrades FKBP12 protein in most organs of treated mice (except brain)
- Efficiently degrades FKBP12 in various organs of Bama pigs and rhesus monkeys
- Effective with oral administration in mice
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Medchemexpress LLC Navocaftor | 2159103-66-7 | 99.2% | 416.33 | 10 MG
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Navocaftor is a protein modulator that acts as a cystic fibrosis transmembrane regulator (CFTR). It is intended for research use only. This compound has a high purity and exhibits specific solubility characteristics for various research applications.
- Solid appearance
- Light yellow to yellow color
- Purity of 99.20%
- Stable for 3 years at -20°C as powder
- Soluble in 10% DMSO, 90% corn oil for in vivo studies
- Acts as a cystic fibrosis transmembrane regulator (CFTR) protein modulator
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eMolecules 2624-66-0 | ChemScene | 14-Dichloro-2-fluoro-5-nitrobenzene | 100mg | 788449336 | CS-0647415 | MFCD25961694 | 209.99 | C6H2Cl2FNO2
Ambeed | 24-Dimethylphenylacetic Acid | 1g | 552748201 | A629579 | 6331-04-0 | MFCD02664685 | 164.204 | C10H12O2
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Medchemexpress LLC Navocaftor | 2159103-66-7 | 99.2% | 416.33 g/mol | C15H11F3N4O5S | 5 MG
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Navocaftor is a small-molecule cystic fibrosis transmembrane conductance regulator (CFTR) potentiator developed for research into restoring or enhancing CFTR channel function. It is supplied as a high-purity research reagent for in vitro and preclinical studies investigating CFTR modulation and combination therapy effects.
- High purity (99.2%).
- Molecular weight 416.3 g/mol.
- Molecular formula C15H11F3N4O5S.
- Intended for research use in CFTR modulation studies.
- Supplied in 5 mg research quantities.
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Medchemexpress LLC N-acetyltyramine | 1202-66-0 | 99.7% | 10 MG
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N-acetyltyramine is the N-acetyl derivative of the biogenic amine tyramine (CAS 1202-66-0). It is supplied for research use and has reported quorum-sensing inhibitory activity; analytical characterization and safety data are available.
- High purity: 99.7%.
- Available as solid packs including 10 mg and as a 10 mM solution in DMSO.
- Comprehensive analytical data available: COA, HPLC, LCMS, and NMR.
- CAS-registered compound for unambiguous identification.
- Intended for research use; consult SDS for handling and safety.
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Medchemexpress LLC (R)-(4,4-difluoropiperidin-1-yl)(1-((4-(isopropylsulfonyl)phenyl)sulfonyl)piperidin-3-yl)methanone | 2749555-66-4 | 99.7% | C20H28F2N2O5S2 | 10MG
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This research compound is a potent inhibitor of mitochondrial oxidative phosphorylation that targets Complex I and is supplied as a solid for laboratory research, with demonstrated low-nanomolar potency and oral activity in preclinical studies.
- Highly potent complex I inhibitor (IC50 = 3.6 nM).
- Impairs ATP generation in cells (IC50 = 11 nM).
- Demonstrated oral bioavailability and in vivo efficacy in preclinical tumor models.
- High chemical purity (99.7%) suitable for biochemical and cellular studies.
- Supplied as a white to off-white solid with recommended low-temperature storage (powder: -20°C) for stability.
- Molecular weight 478.57 g/mol to inform dosing and handling.
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Medchemexpress LLC BPR1M97 | 2059904-66-2 | 99.4% | 50 MG
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BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist. It has Ki values of 1.8 nM for MOP and 4.2 nM for NOP. BPR1M97 exhibits high potency, penetrates the blood-brain barrier, and produces potent antinociceptive effects. It is intended for research use only and is not sold to patients.
- Dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist
- Ki values of 1.8 nM for MOP and 4.2 nM for NOP
- High potency
- Effective blood-brain barrier penetration
- Potent antinociceptive effects
- Intended for research use only
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![eMolecules 57031-66-0 | Ambeed | Methyl 1-methyl-1H-[124]triazole-3-carboxylate | 250mg | 588342297 | A282029 | MFCD13191558 | 141.13 | C5H7N3O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502515874.JPG-250.jpg)
eMolecules 57031-66-0 | Ambeed | Methyl 1-methyl-1H-[124]triazole-3-carboxylate | 250mg | 588342297 | A282029 | MFCD13191558 | 141.13 | C5H7N3O2
Ambeed | Methyl 1-methyl-1H-[124]triazole-3-carboxylate | 250mg | 588342297 | A282029 | 57031-66-0 | MFCD13191558 | 141.130 | C5H7N3O2
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Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 50 MG
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PARP-2-IN-1 is a potent, selective small-molecule inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) with a reported IC50 of 11.5 nM. Supplied as a high-purity powder, it is intended for biochemical and cellular research into DNA repair pathways and target validation studies.
- Potent PARP-2 inhibition with low nanomolar IC50.
- High chemical purity suitable for research use.
- Available in multiple preweighed sizes for experimental flexibility.
- Stable powder with defined cold-storage conditions.
- Suitable for biochemical assays and cellular studies of DNA damage response.
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Medchemexpress LLC BODIPY-FL NHS ester | 146616-66-2 | 99.8% | 389.16 | 50 MG
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BODIPY FL NHS ester is a cell membrane-penetrable amine-reactive fluorescent probe with maximum excitation/emission wavelengths of 502/511 nm. It demonstrates high stability and is unaffected by polarity, pH, or solvent type, maintaining stable fluorescence across various environmental conditions.
- Can be utilized for the synthesis of protease substrates.
- Suitable for live cell imaging.
- Useful for protein labeling.
- Applicable in immunoassay.
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