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Filtered Search Results
Medchemexpress LLC GSK2292767 | 1254036-66-2 | C24H28N6O5S | 5 MG
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GSK2292767 is a potent and selective inhibitor of PI3Kδ, exhibiting a pIC50 of 10.1 and over 500-fold selectivity compared to other PI3K isoforms. It is suitable for respiratory disease research. In vivo studies have shown high clearance (50 mL/min/kg) and low oral bioavailability (F < 2%) in rats. It does not impact QT interval, Tpe, or QRS, and carries no significant risk of TdP arrhythmias in rabbit cardiac ventricular wedge assays.
- Potent and selective PI3Kδ inhibitor
- Greater than 500-fold selectivity over other PI3K isoforms
- Useful for respiratory disease research
- High clearance in rat PK studies
- Low oral bioavailability in rat PK studies
- No significant risk of TdP arrhythmias
- Protects against eosinophil recruitment in a rat model of inflammation
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Medchemexpress LLC 3-indolepropionic acid | 830-96-6 | MFCD00005660 | 99.9% | 189.21 g/mol | C11H11NO2 | 50 MG
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3-Indolepropionic acid is an indole-derived metabolite and antioxidant used as an analytical standard and research reagent. It is commonly applied in biochemical and neuroprotective research, and is suitable for analytical workflows requiring a stable, well-characterized reference compound.
- Indole-derived antioxidant and endogenous metabolite.
- High purity suitable for analytical and research use.
- Supplied as a small-scale standard for assay calibration and method development.
- Compatible with HPLC, LC-MS, and spectroscopic analyses.
- Applicable to studies of neuroprotection and oxidative stress.
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Sigma Aldrich Fine Chemicals Biosciences DAPI for nucleic acid staining | 28718-90-3 | MFCD00012681 | 50mg
DAPI for nucleic acid staining | 250.25 | 28718-90-3 | MFCD00012681 | 50mg
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Medchemexpress LLC 5-methoxytryptamine hydrochloride | 66-83-1 | MFCD00012684 | 99.6% | 226.70 g/mol | C11H15ClN2O | 250 MG
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5-Methoxytryptamine hydrochloride is the hydrochloride salt of 5-methoxytryptamine, a metabolite of melatonin that functions as a nonselective 5-HT (serotonin) receptor agonist. It is provided as a research-grade reagent for studies of serotonin receptor activity, antioxidant effects, and radioprotective actions in biochemical and neuroscience applications.
- Provides a research reagent for serotonin receptor assays.
- Acts as a nonselective 5-HT receptor agonist.
- Exhibits antioxidant and radioprotective properties.
- Formulated as a hydrochloride salt to aid solubility in common solvents.
- Stable under recommended storage: 4°C (solid); in solvent, -80°C (6 months) or -20°C (1 month).
- Characterized by molecular weight 226.70 g/mol and formula C11H15ClN2O.
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eMolecules 5-METHOXY-2-METHYL-1H-INDOL 5G
5000188734 5-METHOXY-2-METHYL-1H-INDOL 5G
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Medchemexpress LLC 6-Methyl-1H-indole | 3420-02-8 | 131.18 | 10 G
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6-Methyl-1H-indole is a biochemical reagent used as a biological material or organic compound for life science research. It serves as a reactant in the preparation of various compounds for medicinal and biological applications.
- Reactant for tryptophan dioxygenase inhibitors, which are potential anticancer immunomodulators
- Reactant for indole-linked triazole derivatives as antifungal agents
- Reactant for N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for managing hyperglycemia in diabetes
- Reactant for aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents
- Reactant for indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
- Reactant for arylsulfonylacetylindoles as anti-HIV-1 agents
- Used in the synthesis of benz[c,d]indol-3(1H)-one derivatives
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Sigma Aldrich Fine Chemicals Biosciences DAPI for nucleic acid staining | 28718-90-3 | MFCD00012681 | 10mg
DAPI for nucleic acid staining | Mol Wt: 350.25 | 28718-90-3 | MFCD00012681 | 10mg
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eMolecules 5-BROMOINDOLE 10G
5000188519 5-BROMOINDOLE 10G
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eMolecules 5-BROMOINDOLE 25G
5000188540 5-BROMOINDOLE 25G
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eMolecules AstaTech / 4-N-OCTYLSTYRENE (STABILIZED WITH TBC) / 0.25g / 448281826 / T72498 / 95.000 / 46745-66-8 / MFCD00078353 / 216.368 / C16H24
AstaTech / 4-N-OCTYLSTYRENE (STABILIZED WITH TBC) / 0.25g / 448281826 / T72498 / 95.000 / 46745-66-8 / MFCD00078353 / 216.368 / C16H24
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eMolecules METHYL INDOLE-7-CARBOXYLATE 5G
5000190094 METHYL INDOLE-7-CARBOXYLATE 5G
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eMolecules Ambeed / Pyrrolidine-2-carboxamide / 250mg / 632172707 / A194943 / / 2812-47-7 / MFCD03788250 / 114.148 / C5H10N2O
Ambeed / Pyrrolidine-2-carboxamide / 250mg / 632172707 / A194943 / / 2812-47-7 / MFCD03788250 / 114.148 / C5H10N2O
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Medchemexpress LLC Sumatriptan succinate (GR 43175 succinate) | 103628-48-4 | 99.9% | 500 MG
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Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nM, 9.3 nM, and 17.8 nM for 5-HT1D, 5-HT1B, and 5-HT1F receptors, respectively. It can be used for migraine headache research.
- Orally active 5-HT1 receptor agonist.
- Targets 5-HT1D, 5-HT1B, and 5-HT1F receptors.
- Effective in migraine headache research.
- Demonstrated to reverse nitroglycerin-induced thermal hypersensitivity in mice (600 μg/kg, i.p. or 0.06 μg in 5 μL, i.t.).
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Medchemexpress LLC Methyl 1H-indole-6-carboxylate | 50820-65-0 | MFCD00211063 | 98.3% | 175.19 g/mol | C10H9NO2 | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Methyl 1H-indole-6-carboxylate is the methyl ester of 1H-indole-6-carboxylic acid used as an organic reagent and synthetic intermediate in medicinal chemistry and biochemical research. Supplied as a powder, it is suitable for use in synthesis, assay development, and as a building block in compound libraries.
- High purity suitable for research applications.
- Molecular formula C10H9NO2 and molecular weight 175.19 g/mol.
- Stable powder with recommended cold storage for long-term preservation.
- Available in multiple pack sizes for small-scale testing or bulk synthesis.
- Certificate of analysis and safety data sheet available.
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![eMolecules Pharmablock / ethyl bicyclo[3.1.0]hexane-3-carboxylate / 25mg / 551224524 / PB92254 / 0.000 / 1509328-66-8 / MFCD23907760 / 154.209 / C9H14O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502485298.JPG-250.jpg)
eMolecules Pharmablock / ethyl bicyclo[3.1.0]hexane-3-carboxylate / 25mg / 551224524 / PB92254 / 0.000 / 1509328-66-8 / MFCD23907760 / 154.209 / C9H14O2
Pharmablock / ethyl bicyclo[3.1.0]hexane-3-carboxylate / 25mg / 551224524 / PB92254 / 0.000 / 1509328-66-8 / MFCD23907760 / 154.209 / C9H14O2
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