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Medchemexpress LLC Thalidomide-NH-PEG3-NH-Boc | 2204246-03-5 | MFCD32694133 | 548.59 g·mol-1 | C26H36N4O9 | 10 MG
Thalidomide-NH-PEG3-NH-Boc is a thalidomide-derived E3 ligase ligand-linker conjugate bearing a three-unit polyethylene glycol spacer and a Boc-protected terminal amine. It is provided as a synthetic intermediate for medicinal chemistry and chemical biology applications, especially for constructing cereblon-recruiting PROTACs.
- Boc-protected terminal amine for controlled deprotection and conjugation.
- PEG3 spacer offers flexibility and improved solubility for bifunctional molecules.
- Designed as an intermediate for CRBN-targeting PROTAC synthesis.
- Soluble in DMSO and compatible with standard in vivo formulation protocols.
- Store frozen to maintain stability.
