Lactams
Apexbio Technology LLC Aztreonam 78110-38-0 100mg
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability
Apexbio Technology LLC Aztreonam 78110-38-0 10mM (in 1mL DMSO)
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability