SIRP gamma Protein a member of signal-regulatory protein (SIRP) family is the only SIRP detected on T cells and activated NK cells SIRP gamma can bind CD47 providing T cells and NK cells with a cell surface molecule capable of interacting with CD47 SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion SIRP gamma Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived SIRP gamma protein expressed by HEK293 with C-His labeled tag