Oxazinanes
Selleck Chemical LLC Diphenylpyraline hydrochloride
Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline which is an antihistamine used in the treatment of allergic rhinitis hay fever and allergic skin disorders
Selleck Chemical LLC Molindone hydrochloride
Molindone hydrochloride is the hydrochloride salt form of molindone a conventional antipsychotic used in the therapy of schizophrenia It is a dopamine D2/D5 receptor antagonist
TARGETMOL CHEMICALS INC Vazegepant hydrochloride 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. Purity 99.56%
TARGETMOL CHEMICALS INC Bisaramil hydrochloride 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Bisaramil hydrochloride (Bisaramil) is a novel diazabicyclononane antiarrhythmic compound that inhibits the generation of free radicals.Bisaramil hydrochloride blocks sodium currents and inhibits the slow Ca(2+) action potential induced by isoproterenol in K(+)-depolarized muscle. Purity 99.64%
Medchemexpress LLC ML-7 hydrochloride | 110448-33-4 | C15H18ClIN2O2S | 5 MG
ML-7 hydrochloride is a naphthalene sulphonamide derivative that potently inhibits Myosin Light Chain Kinase (MLCK) with an IC50 of 300 nM. It also acts as an inhibitor of YAP/TAZ. In vitro studies indicate its ability to inhibit rabbit portal vein α1-adrenoceptor NSCC and attenuate Dexmedetomidine (DMT)-induced contraction. In vivo, ML-7 hydrochloride has been shown to reduce brain edema formation after traumatic brain injury in mice.
- Inhibits Myosin Light Chain Kinase (MLCK)
- Acts as an inhibitor of YAP/TAZ
- Inhibits rabbit portal vein α1-adrenoceptor NSCC
- Attenuates Dexmedetomidine (DMT)-induced contraction
- Reduces brain edema formation after traumatic brain injury in mice
![eMolecules Medchem Express / Desmorpholinyl Navitoclax-NH-Me / 5mg / 536984097 / HY-131232 / / 2365172-82-1 / [null] / 918.550 / C44H51ClF3N5O5S3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502476347.JPG-250.jpg)
eMolecules Medchem Express / Desmorpholinyl Navitoclax-NH-Me / 5mg / 536984097 / HY-131232 / / 2365172-82-1 / [null] / 918.550 / C44H51ClF3N5O5S3
Medchem Express / Desmorpholinyl Navitoclax-NH-Me / 5mg / 536984097 / HY-131232 / / 2365172-82-1 / [null] / 918.550 / C44H51ClF3N5O5S3
Cayman Chemical Methedrone hydrochloride
A phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible MAO inhibitor; intended for use as a standard for the forensic analysis of samples that may contain this compound
TARGETMOL CHEMICALS INC Simmitecan hydrochloride 1MG
Also available in 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors. Purity 98.36%
Cayman Chemical GW 3965 hydrochloride
An orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively; alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism
Medchemexpress LLC N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride | 61714-27-0 | MFCD00012559 | >98.0% | 377.33 g/mol | C16H21ClN2O2S · HCl | 5 MG
W-7 hydrochloride is the hydrochloride salt of W-7, a selective calmodulin antagonist used in biochemical and pharmacological research to inhibit Ca2+-calmodulin-dependent enzymes and modulate calcium-dependent signaling. It is commonly applied in studies of phosphodiesterase regulation, myosin light chain kinase, ion channel function, apoptosis, and vascular relaxation.
- Selective calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase
- Modulates ion channel activity and is used in arrhythmia research
- Available as the hydrochloride salt for improved solubility
- Typical purity >=98% (HPLC)
- Molecular weight ≈377.33 g/mol
- Supplied in small research quantities, e.g., 5 mg
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | MFCD00049357 | 99.8% | 239.23 | 25 MG
7,8-Dihydro-L-biopterin | 6779-87-9 | MFCD00049357 | 99.8% | 239.23 | 25 MG
Apexbio Technology LLC Sinomenine Hydrochloride 6080-33-7 10mM (in 1mL DMSO)
Sinomenine Hydrochloride (CAS 6080-33-7) is an alkaloid derivative isolated from the stems of Sinomenium acutum It acts primarily by modulating the immune response through inhibition of pro-inflammatory cytokine production and suppression of NF- B signaling pathways Sinomenine Hydrochloride has been used in preclinical studies to investigate its anti-inflammatory and immunosuppressive activities particularly in models of rheumatoid arthritis and other autoimmune conditions This compound is suited for use in biomedical research exploring inflammation immune modulation and related therapeutic mechanisms Store in a sealed container under cool dry conditions
![eMolecules ChemScene / 2-Chloro-3-fluoro-5-iodopyridin-4-amine / 100mg / 712787811 / CS-0167775 / 0.000 / 1801841-62-2 / [null] / 272.450 / C5H3ClFIN2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502442171.PNG-250.jpg)
eMolecules ChemScene / 2-Chloro-3-fluoro-5-iodopyridin-4-amine / 100mg / 712787811 / CS-0167775 / 0.000 / 1801841-62-2 / [null] / 272.450 / C5H3ClFIN2
ChemScene / 2-Chloro-3-fluoro-5-iodopyridin-4-amine / 100mg / 712787811 / CS-0167775 / 0.000 / 1801841-62-2 / [null] / 272.450 / C5H3ClFIN2
Cayman Chemical SKF 96365 hydrochloride
Inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels (IC50 = 10 µM); inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM