Oxazinanes
eMolecules 78-90-0 | 1,2-Diaminopropane | Oakwood Chemicals | MFCD00008089 | 74.127 | C3H10N2 | 99.000 | CC(N)CN | 25g | 480145615
1,2-Diaminopropane | Oakwood Chemicals | 78-90-0 | MFCD00008089 | 74.127 | C3H10N2 | 99.000 | CC(N)CN | 25g | 480145615
Apexbio Technology LLC KN-93 hydrochloride 1956426-56-4 10mM (in 1mL DMSO)
KN-93 hydrochloride (CAS 1956426-56-4) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase II (CaMK II) binding competitively at the calmodulin site with a reported Ki of 0 37 M and an IC50 of 370 nM In isolated gastric parietal cells KN-93 suppresses acid secretion stimulated by carbachol and histamine with IC50 values of 0 15 M and 0 3 M respectively and inhibits mucin-stimulated aminopyrine uptake (IC50 0 6 M) Additionally KN-93 shows inhibitory activity against H /K -ATPase and directly blocks voltage-gated potassium (Kv) channels by promoting C-type inactivation KN-93 is widely used to probe CaMK II signaling and its downstream physiological effects in cellular and electrophysiological studies
![eMolecules 959432-77-0 | 4,6-dichloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine | Advanced ChemBlocks | MFCD27934984 | 203.030 | C6H4Cl2N4 | 97.000 | Cn1cc2c(Cl)nc(Cl)nc2n1 | 250mg | 665551888](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 959432-77-0 | 4,6-dichloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine | Advanced ChemBlocks | MFCD27934984 | 203.030 | C6H4Cl2N4 | 97.000 | Cn1cc2c(Cl)nc(Cl)nc2n1 | 250mg | 665551888
4,6-dichloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine | Advanced ChemBlocks | 959432-77-0 | MFCD27934984 | 203.030 | C6H4Cl2N4 | 97.000 | Cn1cc2c(Cl)nc(Cl)nc2n1 | 250mg | 665551888
Medchemexpress LLC Bersiporocin | 2241808-52-4 | 99.0% | 328.24 g/mol | C15H19Cl2N3O | 5 MG
Bersiporocin is a small-molecule prolyl-tRNA synthetase (PRS) inhibitor used in preclinical research to study antifibrotic mechanisms and collagen synthesis modulation. Supplied as a high-purity solid, it is suitable for in vitro and in vivo formulation with documented solubility in DMSO and recommended low-temperature storage for stability.
- High purity (≈99%) suitable for research applications.
- Potent PRS inhibition for antifibrotic research.
- Soluble in DMSO at high concentration for in vitro studies.
- Available in small mg quantities for early-stage experiments.
- Stability data provided for low-temperature storage.
Medchemexpress LLC HADA hydrochloride | 2253733-10-5 | 98.0% | 250 MG
HADA hydrochloride is a blue fluorescent D-amino acid that is efficiently incorporated into the peptidoglycans of diverse bacterial species at the sites of peptidoglycan biosynthesis. This allows for specific and covalent probing of bacterial growth with minimal perturbation.
- Blue fluorescent D-amino acid (λem~450 nm)
- Efficiently incorporated into peptidoglycans of diverse bacterial species
- Allows specific and covalent probing of bacterial growth
- Causes minimal perturbation to bacterial growth
Cayman Chemical Dimebolin hydrochloride
A neuroprotective agent; binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as α1A-, α1B-, α1D-, and α2A-ARs, imidazoline I2 receptors, and 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 receptors (Kis = 8-313 nM); inhibits NMDA-evoked currents and voltage-gated calcium channels in mouse primary striatal neurons (IC50s = 10 and 50 μM, respectively); inhibits glutamate-induced apoptosis in primary striatal neurons derived from the YAC128 transgenic mouse model of Huntington’s disease at 50 μM; inhibits cell death induced by amyloid-β (25-35) in cerebellar granule cells at 25 μM; inhibits decreases TWAA acquisition in a rat model of AF64A-induced Alzheimer’s disease at 1 mg/kg