Oxazinanes
![eMolecules 1577233-70-5 | 3-[(Tributylstannyl)methoxy]-1-propanamine | Synthonix - Stock | MFCD28579830 | 378.188 | C16H37NOSn | 98.000 | CCCC[Sn](CCCC)(CCCC)COCCCN | 1g | 525924099](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696551.jpg-250.jpg)
eMolecules 1577233-70-5 | 3-[(Tributylstannyl)methoxy]-1-propanamine | Synthonix - Stock | MFCD28579830 | 378.188 | C16H37NOSn | 98.000 | CCCC[Sn](CCCC)(CCCC)COCCCN | 1g | 525924099
3-[(Tributylstannyl)methoxy]-1-propanamine | Synthonix - Stock | 1577233-70-5 | MFCD28579830 | 378.188 | C16H37NOSn | 98.000 | CCCC[Sn](CCCC)(CCCC)COCCCN | 1g | 525924099
TARGETMOL CHEMICALS INC REGORAFENIB HYDROCHLORID 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activitypurity: 100%
Selleck Chemical LLC Delapril Hydrochloride
Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril which is a lipophilic non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity
Apexbio Technology LLC AT7519 Hydrochloride 902135-91-5 10mM (in 1mL DMSO)
AT7519 Hydrochloride (CAS 902135-91-5) is a small-molecule inhibitor of cyclin-dependent kinases (CDKs) which are critical regulators of cell proliferation division and apoptosis in eukaryotic cells By targeting multiple CDKs including CDK1 and CDK2 AT7519 induces cell cycle arrest and apoptosis in various human tumor cell lines demonstrating inhibitory activity with IC50 values ranging from 40 to 940 nmol/L In preclinical studies it suppressed tumor growth in xenograft models and promoted tumor cell apoptosis AT7519 is under clinical evaluation for the treatment of refractory solid tumors supporting its utility in cancer research and drug development
Apexbio Technology LLC Pitolisant hydrochloride 903576-44-3 10mM (in 1mL DMSO)
Pitolisant hydrochloride (CAS 903576-44-3) also known as BF2 649 or Ciproxidine is a potent and selective non-imidazole inverse agonist of the histamine H3 receptor exhibiting a Ki of 0 16 nM for the human recombinant receptor By targeting the H3 autoreceptor pitolisant modulates histaminergic neurotransmission and regulates the release of other neurotransmitters In vitro it demonstrates higher intrinsic activity than ciproxifan and an EC50 of 1 5 nM Pitolisant is orally bioavailable and increases brain tele-methylhistamine levels in rodents in a dose-dependent manner reflecting activation of histaminergic neurons It is widely applied in studies related to cognition epilepsy and models of neuropsychiatric disorders
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 1 ML
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor. It exhibits IC50s of 5 nM for Akt1, 18 nM for Akt2, and 8 nM for Akt3. This product is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor
- IC50s of 5 nM for Akt1, 18 nM for Akt2, and 8 nM for Akt3
- Purity 99.19%
- Molecular weight 530.92
- Chemical formula C24H34Cl3N5O2
- Provided as a 10 mM solution in DMSO
Medchemexpress LLC 7,8-Dihydro-L-biopterin (Standard) | 6779-87-9 | 99.8% | 239.23 | 10 MG
7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. It is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. It promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. It is sensitive to the inhibitory effect of SOD.
- Can be applied to research related to salt-sensitive hypertension.
- Can be applied to research related to moderate to severe traumatic brain injury.
- Can be applied to research related to neurodegenerative diseases.
Selleck Chemical LLC Vazegepant hydrochloride
Vazegepant hydrochloride (BHV-3500 Zavegepant) is a highly potent selective and structurally unique small molecule antagonist of CGRP receptor It can also be used for the acute treatment of migraine
eMolecules 54396-44-0 | 2-Methyl-3-(trifluoromethyl)aniline | Ambeed | MFCD00153216 | 175.154 | C8H8F3N | 97.000 | Cc1c(N)cccc1C(F)(F)F | 10g | 552641659
2-Methyl-3-(trifluoromethyl)aniline | Ambeed | 54396-44-0 | MFCD00153216 | 175.154 | C8H8F3N | 97.000 | Cc1c(N)cccc1C(F)(F)F | 10g | 552641659
Medchemexpress LLC Vacquinol-1 dihydrochloride (NSC13316 dihydrochloride) | 2309312-85-2 | 99.7% | 425.78 | 100 MG
Vacquinol-1 (NSC13316) dihydrochloride is a MKK4-specific activator that activates MAPK pathways. It specifically induces human glioblastoma cell (GC) death, attenuates tumor progression, and prolongs survival in a glioblastoma multiforme (GBM) mouse model. Vacquinol-1 dihydrochloride also induces apoptosis in hepatocellular carcinoma (HCC) cells.
- Activates MAPK pathways
- Induces human glioblastoma cell death
- Attenuates tumor progression
- Prolongs survival in a glioblastoma multiforme mouse model
- Induces apoptosis in hepatocellular carcinoma cells
Medchemexpress LLC Tirbanibulin dihydrochloride | 1038395-65-1 | MFCD20526429 | 98.0% | 504.45 g/mol | C26H31Cl2N3O3 | 50 MG
Tirbanibulin dihydrochloride is a research-grade small-molecule inhibitor that targets Src kinase and microtubule/tubulin dynamics. Supplied as a solid for in vitro and preclinical laboratory studies, it is provided with analytical characterization and storage guidance. For research use only; not for human therapeutic use.
- Targets Src and microtubule/tubulin.
- Cas number: 1038395-65-1.
- Molecular formula: C26H31Cl2N3O3.
- Molecular weight: 504.45 g/mol.
- Purity: 98.02% (reported).
- Appearance: solid; recommended storage 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Supplied as a solid; common package size: 50 MG.
Medchemexpress LLC 5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid | 956317-36-5 | 99.99% | C10H9N3O2 | 10 G
5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid is a chemical compound used as a laboratory reagent and in the manufacture of other substances. This white to off-white solid is characterized by its high purity and specific storage requirements.
- High purity (99.99%)
- Suitable for laboratory chemicals and manufacture of other substances
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- In solvent, stable at -80°C for 6 months or -20°C for 1 month
- Appears as a white to off-white solid
TARGETMOL CHEMICALS INC EGFR-IN-1 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride exhibits potent antitumor and antiproliferative activity in H1975 cells and the mutant HCC827 cells with IC50s of 4 and 28 nM respectively. purity: 99%
Medchemexpress LLC 5,6-Dihydro-5-methyluracil | 696-04-8 | 250 MG
5,6-Dihydro-5-methyluracil, also known as Dihydrothymine, is an intermediate breakdown product of thymine found in animals and plants. This substance is intended for laboratory use and research purposes only, and can be toxic at abnormally high levels.
- Intermediate breakdown product of thymine
- Found in animals and plants
- Can be toxic at abnormally high levels
- For research use only
- Appears as a white to off-white solid
- Stable under recommended storage conditions
eMolecules 27776-21-2 | 1,2-Bis(2-(4,5-dihydro-1H-imidazol-2-yl)propan-2-yl)diazene dihydrochloride | Oakwood Chemicals | MFCD00142723 | 323.270 | C12H24Cl2N6 | 98.000 | Cl.Cl.CC(C)(\N=N\C(C)(C)C1=NCCN1)C1=NCCN1 | 10g | 480160276
1,2-Bis(2-(4,5-dihydro-1H-imidazol-2-yl)propan-2-yl)diazene dihydrochloride | Oakwood Chemicals | 27776-21-2 | MFCD00142723 | 323.270 | C12H24Cl2N6 | 98.000 | Cl.Cl.CC(C)(\N=N\C(C)(C)C1=NCCN1)C1=NCCN1 | 10g | 480160276