Oxazinanes
TARGETMOL CHEMICALS INC ML-7 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML-7 hydrochloride (ML-7 HCl) is a cell-permeable reversible effective ATP-competitive and specific inhibitor of myosin light chain kinase (Ki 300 nM); also inhibits smooth-muscle myosin light chain kinase PKA and PKC. purity: 99%
TARGETMOL CHEMICALS INC LINSIDOMINE HYDROCHLORID 5MG
Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine with vasodilation inhibition of platelet aggregation and antiangina activity. In myocardial ischemia-reperfusion models Linsidomine hydrochloride to reduce myocardial necrosis and reperfusion induced endothelial dysfunction is associated with the cavernosal mechanism of action involved in nitric oxide release. purity: 99%
TARGETMOL CHEMICALS INC SALUBRINAL 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Salubrinal a phosphatases (PP1) inhibitor(IC50=1.7 uM) exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2(alpha)). purity: 99%
TARGETMOL CHEMICALS INC DASATINIB HYDROCHLORIDE 50MG
Also available in 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent ATP competitive orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy. purity: 99%
Selleck Chemical LLC Colesevelam Hydrochloride
Colesevelam Hydrochloride is an orally administered non-absorbable polymeric bile-acid-binding agent with a higher affinity for glycocholic acid in vitro
eMolecules Maltoheptaose | 34620-78-5 | MFCD00064605 | 250mg
Combi-Blocks, Inc. | Maltoheptaose | 250mg | 603152127 | QB-5747 | 95.000 | 34620-78-5 | MFCD00064605 | 1153.002 | C42H72O36
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eMolecules 1031667-63-6 | 2H-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 3,4-DIHYDRO-3-METHYL-, METHYL ESTER | MFCD26664584 | 1g
Ambeed | Methyl 3-amino-5-fluoropicolinate | 100mg | 517260738 | A479504 | 1052714-11-0 | MFCD18259055 | 170.143 | C7H7FN2O2
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Apexbio Technology LLC YM-155 hydrochloride 355406-09-6 10mM (in 1mL DMSO)
YM-155 hydrochloride (CAS 355406-09-6) is a small molecule inhibitor that selectively targets survivin the smallest member of the inhibitor of apoptosis (IAP) protein family Unlike broader IAP inhibitors YM-155 preferentially reduces survivin expression without significantly affecting related family proteins or BCL-2 proteins Treatment with YM-155 has demonstrated antiproliferative activity across diverse human tumor cell lines and induced tumor regression in preclinical xenograft models of non-small cell lung cancer (NSCLC) melanoma bladder cancer aggressive non-Hodgkin lymphoma and breast cancer Additionally YM-155 reduced metastatic potential and prolonged survival in animal models bearing triple-negative breast cancer xenografts highlighting its utility in cancer research
TARGETMOL CHEMICALS INC PD0166285 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator. purity: 99%
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
TARGETMOL CHEMICALS INC VILAZODONE HYDROCHLORIDE 200MG
Also available in 10 mg 50 mg 100 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vilazodone Hydrochloride (EMD 68843) a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI) is utilized in treating of the major depressive disorder. purity: 99%
TARGETMOL CHEMICALS INC CILASTATIN 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic IMIPENEM is hydrolyzed by dehydropeptidase-I which resides in the brush border of the renal tubule cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. purity: 99%
