Oxazinanes
TARGETMOL CHEMICALS INC SKF-96365 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SKF-96365 hydrochloride (SKF96365) a SOCE inhibitor exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autophagy to delay apoptosis by preventing the release of cytochrome c (cyt c) from the mitochondria into the cytoplasm. Mechanistically SKF-96365 hydrochloride treatment inhibited the calcium/calmodulin-dependent protein kinase II(gamma) (CaMKII(gamma))/AKT signaling cascade in vitro and in vivo. Overexpression of CaMKII(gamma) or AKT abolished the effects of SKF-96365 on Y cells suggesting a critical role of the CaMKII(gamma)/AKT signaling pathway in SFK-96365-induced biological effects. SKF-96365 hydrochloride inhibited hERG current in a concentration-dependent manner. purity: 99%
TARGETMOL CHEMICALS INC TIPLAXTININ 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM. purity: 99%
TARGETMOL CHEMICALS INC A 77636 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. A 77636 hydrochloride is a potent orally active selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionally inactive at dopamine D2 receptor. purity: 99%
eMolecules ChemScene 25-Dibromopyridin-3-amine 5g 536793574 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
ChemScene 25-Dibromopyridin-3-amine 5g 536793574 CS-0052143 90902-84-4 MFCD09266224 251.909 C5H4Br2N2
eMolecules J W PharmLab LLC (S)-Morpholin-2-yl-methanol 250mg 642183826 53R0305 96 000 132073-83-7 MFCD09260718 117 148 C5H11NO2
J W PharmLab LLC (S)-Morpholin-2-yl-methanol 250mg 642183826 53R0305 96 000 132073-83-7 MFCD09260718 117 148 C5H11NO2
Medchemexpress LLC Tebanicline dihydrochloride | 209326-19-2 | 99.5% | C9H13Cl3N2O | 50 MG
Tebanicline dihydrochloride is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM.
- nAChR modulator
- Potent and orally effective analgesic activity
- Inhibits binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM
- Potent antinociceptive agent with full efficacy in models of acute and persistent pain
- Produces significant antinociceptive effects in mice against acute noxious thermal stimulation
- Orally active
- Has antinociceptive effects in rat models of acute thermal, persistent chemical, and neuropathic pain
eMolecules ChemScene tert-Butyl ((1R2S)-2-aminocyclohexyl)carbamate 25g 632281275 CS-0137432 364385-54-6 MFCD09952106 214.309 C11H22N2O2
ChemScene tert-Butyl ((1R2S)-2-aminocyclohexyl)carbamate 25g 632281275 CS-0137432 364385-54-6 MFCD09952106 214.309 C11H22N2O2
eMolecules ChemScene tert-Butyl ((1R2S)-2-aminocyclohexyl)carbamate 5g 632281274 CS-0137432 364385-54-6 MFCD09952106 214.309 C11H22N2O2
ChemScene tert-Butyl ((1R2S)-2-aminocyclohexyl)carbamate 5g 632281274 CS-0137432 364385-54-6 MFCD09952106 214.309 C11H22N2O2
![eMolecules Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695158.jpg-250.jpg)
eMolecules Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd
Combi-Blocks Inc. Chloro[(tricyclohexylphosphine)-2-(2'-aminobiphenyl)]palladium(II) 5g 642135149 QH-3261 96.000 1353658-81-7 [null] 590.520 C30H43ClNPPd
eMolecules ChemScene Morpholine-2-carbonitrile hydrochloride 1g 632312733 CS-W005833 1205751-07-0 MFCD14582597 148.590 C5H9ClN2O
ChemScene Morpholine-2-carbonitrile hydrochloride 1g 632312733 CS-W005833 1205751-07-0 MFCD14582597 148.590 C5H9ClN2O
![eMolecules Synthonix - Stock 6-Boc-octahydropyrrolo[23-c]pyridine 250mg 525911796 B8256 1196147-27-9 MFCD13189555 226.320 C12H22N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696903.jpg-250.jpg)
eMolecules Synthonix - Stock 6-Boc-octahydropyrrolo[23-c]pyridine 250mg 525911796 B8256 1196147-27-9 MFCD13189555 226.320 C12H22N2O2
Synthonix - Stock 6-Boc-octahydropyrrolo[23-c]pyridine 250mg 525911796 B8256 1196147-27-9 MFCD13189555 226.320 C12H22N2O2
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride reag25KG
Trizma(R) hydrochloride is mainly required for preparation of buffer at physiological range of 7.3 to 7.5. The prepared buffer is compatible with biological fluids. It is of importance to laboratories as a standard pH SOLUTIONon.
