Oxazinanes
TARGETMOL CHEMICALS INC CSRM617 HYDROCHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2 a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]purity: 99%
Medchemexpress LLC Mmpip hydrochloride | 1215566-78-1 | 99.1% | 369.80 g/mol | C19H16ClN3O3 | 1 ML
MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist supplied as a ready-to-use 10 mM solution in dimethyl sulfoxide (DMSO). It is intended for in vitro pharmacology and receptor modulation studies and is provided with high purity and characterized identity.
- Allosteric mGluR7 antagonist for receptor modulation studies.
- Provided as a 10 mM solution in DMSO for immediate use.
- High purity suitable for pharmacological assays.
- Available in multiple solid and solution pack sizes for flexibility.
- Characterized by CAS 1215566-78-1 and confirmed molecular weight of 369.80 g/mol.
TARGETMOL CHEMICALS INC K34C HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. K34c hydrochloride is an alpha5(beta)1 integrin antagonist for glioblastoma study.
Selleck Chemical LLC Ribociclib hydrochloride S5187-25mg
Ribociclib (LEE011) hydrochloride is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.69% | C21H30Cl2N2O2 | 25 MG
Decloxizine dihydrochloride is a histamine 1 receptor antagonist.
- H1 receptor antagonist
- Suitable for neurological research
- Applicable in studies of eye or ear disease
- Relevant for metabolic or endocrine disease research
- Used in inflammation or immune system disease studies
- Involved in neurodegenerative disease research
- Related to lipid metabolism
- Applicable to Parkinson's disease research
- Relevant for obesity studies
- Used in endocrinology research
Medchemexpress LLC Bay 61-3606 dihydrochloride | 648903-57-5 | MFCD08276916 | 99.5% | 463.32 g·mol^-1 | C20H20Cl2N6O3 | 10 MG
BAY 61-3606 dihydrochloride is a potent, ATP-competitive, reversible, and highly selective inhibitor of spleen tyrosine kinase (Syk), provided as the dihydrochloride salt for research use. It is intended for biochemical and cell-based studies of kinase signaling and apoptosis, and has reported biochemical potency (Ki = 7.5 nM; IC50 ≈ 10 nM) and high purity for reliable experimental results.
- High biochemical potency (Ki = 7.5 nM; IC50 ≈ 10 nM).
- High reported purity (≈99.5%).
- Provided as dihydrochloride salt suitable for cell-based assays.
- Characterized by COA, HNMR, and LC-MS documentation.
- Useful for studying Syk-dependent signaling and apoptosis.
TARGETMOL CHEMICALS INC ML-7 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML-7 hydrochloride (ML-7 HCl) is a cell-permeable reversible effective ATP-competitive and specific inhibitor of myosin light chain kinase (Ki 300 nM); also inhibits smooth-muscle myosin light chain kinase PKA and PKC. purity: 99%
TARGETMOL CHEMICALS INC LP-922761 5MG
Also available in 1 mg and bulk. Please contact Fisher for quotes. LP-922761 is a potent selective and orally active AAK1 inhibitor with inhibitory effects on BMP-2 induced protein kinase (BIKE). purity: 97%
![Medchemexpress LLC 1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 5334-56-5 | MFCD01312343 | 150.14 g/mol | C6H6N4O | 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209958.png-250.jpg)
Medchemexpress LLC 1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 5334-56-5 | MFCD01312343 | 150.14 g/mol | C6H6N4O | 5 G
1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 5334-56-5) is a pyrazolopyrimidinone small-molecule used as a biochemical reagent and reference compound in life-science research.
- Chemical formula C6H6N4O, molecular weight 150.14 g/mol.
- Solid form with a reported melting point >250 °C.
- Commonly used as a biochemical reagent and reference compound in pharmacological and biochemical studies.
- Typical supplier package sizes include small gram quantities for research use.
- Reported purities vary by supplier; verify the exact purity from the product-specific safety data sheet or manufacturer listing.
Cayman Chemical SRT 1720 hydrochloride
A selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol; improves insulin sensitivity, lowers plasma, glucose and increases mitochondrial capacity in diet-induced obese and diabetic leptin-deficient ob/ob mice after one week of treatment with an oral dose of 100 mg/kg once daily.
CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1 | 100mg | 348528136](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697893.jpg-250.jpg)
eMolecules 923564-51-6 | Navitoclax | Target Molecule | MFCD12756219 | 974.610 | C47H55ClF3N5O6S3 | 0.000 | CC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCOCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1 | 100mg | 348528136
Navitoclax | Target Molecule | 923564-51-6 | MFCD12756219 | 974.610 | C47H55ClF3N5O6S3 | 0.000 | CC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCOCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1 | 100mg | 348528136
Selleck Chemical LLC Rauwolscine hydrochloride S5337-25mg
Rauwolscine hydrochloride (Isoyohimbine -Yohimbine corynanthidine) is the hydrochloride salt form of Rauwolscine a specific and potent 2 antagonist with Ki of 12 nM
eMolecules 1420898-14-1 | tert-Butyl 3-(cyclopropylamino)-3-methylpiperidine-1-carboxylate | ChemScene | MFCD24383571 | 254.374 | C14H26N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(C)(C1)NC1CC1 | 100mg | 811576827
tert-Butyl 3-(cyclopropylamino)-3-methylpiperidine-1-carboxylate | ChemScene | 1420898-14-1 | MFCD24383571 | 254.374 | C14H26N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(C)(C1)NC1CC1 | 100mg | 811576827
Cayman Chemical FR122047 hydrochloride
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis
Selleck Chemical LLC Amodiaquine hydrochloride
Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties