Oxazinanes
Medchemexpress LLC 2,5-Dimethyl-3(2H)-furanone | 14400-67-0 | 98.0% | 112.13 | 1 G
2,5-Dimethyl-3(2H)-furanone is a furanone-based fragrance compound. It has been noted to have no ability to damage DNA and no genetic toxicity.
- Type of furanone-based fragrance compound.
- No ability to damage DNA.
- No genetic toxicity.
eMolecules 2905-25-1 | 2-Bromobenzenesulphonyl chloride | Ambeed | MFCD00051971 | 255.510 | C6H4BrClO2S | 98.000 | ClS(=O)(=O)c1ccccc1Br | 1g | 531647901
2-Bromobenzenesulphonyl chloride | Ambeed | 2905-25-1 | MFCD00051971 | 255.510 | C6H4BrClO2S | 98.000 | ClS(=O)(=O)c1ccccc1Br | 1g | 531647901
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 1 G
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, demonstrating significant selectivity against Akt1, Akt2, and Akt3. It is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor
- IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively
- Exhibits over 600-fold and over 100-fold selectivity for Akt1 against PKA and p70S6K
- Effective in xenograft models with Akt activation
- Achieves tumor growth delay, stasis, or regression in vivo
eMolecules 6968-35-0 | 7-Hydroxy-2,3-dihydro-1H-inden-1-one | Ambeed | MFCD01548387 | 148.161 | C9H8O2 | 97.000 | Oc1cccc2CCC(=O)c12 | 250mg | 552533671
7-Hydroxy-2,3-dihydro-1H-inden-1-one | Ambeed | 6968-35-0 | MFCD01548387 | 148.161 | C9H8O2 | 97.000 | Oc1cccc2CCC(=O)c12 | 250mg | 552533671
Medchemexpress LLC Amodiaquine dihydrochloride dihydrate | 6398-98-7 | 99.9% | 1 ML
Amodiaquine dihydrochloride dihydrate is a 4-aminoquinoline class antimalarial agent. It functions as a potent and orally active inhibitor of histamine N-methyltransferase and acts as a Nurr1 agonist. This compound also exhibits anti-inflammatory and neuroprotective effects, suppressing pro-inflammatory cytokines.
- Antimalarial agent, effective against malaria.
- Potent and orally active histamine N-methyltransferase inhibitor.
- Nurr1 agonist, specifically binds to the Nurr1-LBD with an EC50 of ~20 μM.
- Anti-inflammatory effects.
- Solution form: available as a 10 mM * 1 mL solution in DMSO with a purity of 99.92%.
- Neuroprotective effects: inhibits neurotoxin-induced cell death in primary dopamine cells and has effects in rat PC12 cells.
- Suppresses LPS-induced expression of pro-inflammatory cytokines.
Medchemexpress LLC Amodiaquine dihydrochloride | 69-44-3 | 99.9% | 50 MG
Amodiaquine dihydrochloride is a 4-aminoquinoline class antimalarial agent. It is a potent and orally active histamine N-methyltransferase inhibitor. This compound also acts as a Nurr1 agonist and exhibits anti-inflammatory effects. It is intended for research use only.
- Potent and orally active histamine N-methyltransferase inhibitor
- Nurr1 agonist with anti-inflammatory effects
- Inhibits 6-OHDA-induced cell death in primary dopamine cells
- Suppresses LPS-induced expression of proinflammatory cytokines
Apexbio Technology LLC VERNAKALANT-HYDROCHLORIDE-2MG
Vernakalant Hydrochloride (CAS No 748810-28-8) is an antiarrhythmic agent primarily used in biomedical research to explore cardiac electrophysiology It originates from efforts to develop treatments for atrial fibrillation by selectively targeting ion channels specifically potassium channels in cardiac tissue therefore stabilizing abnormal heart rhythms The compound s mechanism of action involves blocking atrial-specific potassium currents resulting in an effective restoration of normal rhythm without affecting ventricular tissues In vitro Vernakalant Hydrochloride exhibits activity typically in the nanomolar to low micromolar range Researchers commonly utilize it in cell models and animal studies to investigate cardiac disorders as well as in drug screening assays to assess its therapeutic potential and safety profile Experimental concentrations typically depend on the specific research design ensuring adequate testing conditions for various study parameters
Apexbio Technology LLC YONKENAFIL-HYDROCHLORIDE-1MG
Yonkenafil hydrochloride (CAS No 804519-64-0) is a compound extensively studied within the field of biomedical research for its potential therapeutic effects Originating as a research chemical it is known to act on phosphodiesterase (PDE) pathways particularly targeting the PDE5 enzyme which plays a significant role in vasodilation processes Its in vitro activity is often noted in the nanomolar to low micromolar range making it suitable for potent pharmacological interventions Typical applications include use in various cell models and animal studies to explore cardiovascular or reproductive health implications as well as in drug screening protocols to assess efficacy and safety Experimental concentrations typically depend on the specific research design allowing for flexible integration into different experimental frameworks