Oxazinanes
Apexbio Technology LLC LEE011-HYDROCHLORIDE-2MG
LEE011 hydrochloride (CAS No 1211443-80-9) is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor primarily utilized in oncology research It originates from the need to halt the progression of cancer cells by disrupting the cell cycle targeting the CDK4/6-Rb pathway In vitro LEE011 hydrochloride demonstrates efficacy in the nanomolar to low micromolar range effectively inhibiting cell proliferation across various cancer cell lines It is frequently employed in cell models and animal studies to evaluate its therapeutic potential and synergy with other anticancer agents Additionally this compound is widely used in drug screening and preclinical trials to assess its viability as a treatment option Experimental concentrations typically depend on the specific research design ensuring its application is tailored to the desired outcomes in scientific investigations
Apexbio Technology LLC AMODIAQUINE-HYDROCHLORIDE
Amodiaquine hydrochloride (CAS No 69-44-3) is an antimalarial agent primarily employed in biomedical research to explore its antiprotozoal properties and mechanisms of action Originating from the class of 4-aminoquinolines it acts by inhibiting heme polymerase disrupting heme detoxification in plasmodium parasites Its in vitro activity has been reported in the nanomolar to low micromolar range making it potent in various experimental settings Amodiaquine hydrochloride is frequently utilized in cell models and animal studies to evaluate its efficacy and safety profile and in drug screening assays to identify potential therapeutic candidates Experimental concentrations typically depend on the specific research design ensuring applicability across a range of scientific investigations
Medchemexpress LLC 1,3-Dioxolane-4-ethanol, 2,2-di-(9Z,12Z)-9,12-octadecadien-1-yl- | 1190203-55-4 | C41H74O3 | 250 MG
LNP Lipid-7 is a cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of drugs, such as nucleic acids.
- Used to prepare lipid nanoparticles (LNPs) for drug delivery
- Cationic lipid
- Purity of 95.0%
- Molecular weight of 615.02
- Liquid appearance, colorless to light yellow
- Density of 0.901 g/cm³
![Medchemexpress LLC Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride (1:2) | 69-44-3 | 99.97% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000411980-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride (1:2) | 69-44-3 | 99.97% | 1 ML
Amodiaquine dihydrochloride is a 4-aminoquinoline antimalarial agent that is orally active. It functions as a potent inhibitor of histamine N-methyltransferase with a Ki of 18.6 nM, and also acts as a Nurr1 agonist, binding specifically to its ligand-binding domain with an EC50 of approximately 20 μM. This compound also demonstrates anti-inflammatory effects and is for research use only.
- Purity: 99.97%
- Molecular weight: 428.78
- Formula: C20H24Cl3N3O
- CAS number: 69-44-3
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility: Greater than or equal to 125 mg/mL in DMSO (requires sonication), greater than or equal to 50 mg/mL in water (requires sonication)
Apexbio Technology LLC PROPACETAMOL-HYDROCHLORIDE
Propacetamol hydrochloride (CAS No 66532-86-3) is a prodrug of paracetamol commonly used in biomedical research for its analgesic and antipyretic properties It originates from the enzymatic conversion process where it rapidly hydrolyzes to release paracetamol which then exerts its effects by inhibiting cyclooxygenase enzymes and reducing the synthesis of prostaglandins in the central nervous system In vitro studies often show activity in the nanomolar to low micromolar range indicating its potent efficacy Typically it is used in cell models and animal studies to investigate pain management mechanisms and in drug screening strategies for analgesic development Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Cetylpyridinium chloride monohydrate | 6004-24-6 | 99.8% | 1 ML
Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound that functions as an antiseptic, effectively killing bacteria and other microorganisms. It is commonly used in various oral hygiene products to prevent plaque and reduce gingivitis. This compound also exhibits biological activity against viruses and in cellular models, and has been studied in clinical trials for conditions such as SARS-CoV-2 infection and periodontal diseases.
- Cationic quaternary ammonium compound
- Functions as an antiseptic
- Kills bacteria and other microorganisms
- Prevents plaque and reduces gingivitis
- Used in mouthwashes, toothpastes, and throat/nasal sprays
- Disrupts influenza viral envelope
- Exhibits dose-dependent cytotoxicity in MDCK cells
- Enhances survival and reduces influenza-associated morbidity and mortality in mice
Aobchem (2-Chloro-5-ethylphenyl)boronic acid | ≥95% | CAS 1418023-51-4 | C8H10BClO2 | 500mg
(2-Chloro-5-ethylphenyl)boronic acid | ≥95% | CAS 1418023-51-4 | C8H10BClO2 | 500mg