Oxazinanes
Medchemexpress LLC Tebanicline dihydrochloride | 209326-19-2 | 99.5% | C9H13Cl3N2O | 1 ML
Tebanicline dihydrochloride is a potent, orally effective analgesic that modulates neuronal nicotinic acetylcholine receptors (nAChRs). It exhibits high selectivity for neuronal nAChRs, acting as an agonist, and effectively inhibits cytisine binding to α4β2 neuronal nAChRs. This product is investigated for its potential in treating various types of pain and for its anxiolytic-like properties.
- Potent and orally effective analgesic.
- Highly selective for neuronal nAChRs.
- Shows efficacy in models of acute, persistent, chemical, and neuropathic pain.
- Investigated for anxiolytic-like activity.
TARGETMOL CHEMICALS INC DROBULINE HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity. purity: 98%
eMolecules ChemScene / 2-(4-Morpholinyl)-3-pyridinamine / 250mg / 714112581 / CS-0206941 / 0.000 / 51627-47-5 / MFCD03001243 / 179.223 / C9H13N3O
ChemScene / 2-(4-Morpholinyl)-3-pyridinamine / 250mg / 714112581 / CS-0206941 / 0.000 / 51627-47-5 / MFCD03001243 / 179.223 / C9H13N3O
Medchemexpress LLC (6S)-CP-470711 | 300552-09-4 | 98.8% | 358.44 | C18H26N6O2 | 10 MG
(6S)-CP-470711 is a research-grade small-molecule inhibitor of sorbitol dehydrogenase (SDH). Supplied as a powder in small research pack sizes, it has low-nanomolar potency against human and rat SDH and is intended for laboratory research use.
- Low-nanomolar SDH inhibitor (human IC50 19 nM; rat IC50 27 nM).
- Powder form suitable for storage and handling.
- Purity 98.75% by manufacturer specification.
- Chemical formula C18H26N6O2; molecular weight 358.44.
- Available in small pack sizes, including a 10 mg pack.
- Storage: powder -20°C for up to 3 years; in solvent -80°C for up to 6 months.
TARGETMOL CHEMICALS INC JW 55 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JW 55 (JW55) is an effective and selective (beta)-catenin signaling pathway inhibitor works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). purity: 99%
TARGETMOL CHEMICALS INC AB928 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AB928 is an orally bioavailable selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1]. purity: 98%
TARGETMOL CHEMICALS INC RAC-ACOLBIFENE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profilerelative binding affinity (RBA)=380. purity: 98%
Medchemexpress LLC Prexasertib dihydrochloride | 1234015-54-3 | MFCD25977016 | 99.7% | 10 MG
Prexasertib dihydrochloride is a selective, ATP-competitive CHK1 inhibitor used in preclinical research to probe checkpoint signaling, replication stress, and DNA damage-induced apoptosis. It is suitable for biochemical and cellular assays investigating antitumor mechanisms and pathway dependencies.
- High potency against CHK1 (Ki 0.9 nM; IC50 <1 nM).
- Also inhibits CHK2 and RSK1 at low nanomolar concentrations (CHK2 IC50 8 nM; RSK1 IC50 9 nM).
- Available as solid powder and as DMSO solutions for flexible assay formats.
- Reported high purity appropriate for preclinical studies.
- Useful for studies of DNA damage response, replication catastrophe, and apoptosis.
TARGETMOL CHEMICALS INC VARDENAFIL HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1 respectively. purity: 99%