Oxazinanes
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES TRIPROLIDINE HYDROCHLORIDE 1G
NC3373054 TRIPROLIDINE HYDROCHLORIDE 1G
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
A series of Pre-mixed SOLUTIONons of TRIZMA Base and TRIZMA HCl to provide commonly used pH values for Tris buffers. No mixing or pH adjustment necessary. Guaranteed accuracy /- 0.1 pH units.
Selleck Chemical LLC CCT241533 hydrochloride-1MG
CCT241533 hydrochloride is an ATP competitive potent and selective inhibitor of CHK2 with an IC50 of 3 nM and a Ki of 1 16 nM and shows minimal cross-reactivity against a panel of kinases CCT241533 inhibits CHK2 activity in human tumor cell lines when subjected to DNA damage
Medchemexpress LLC Mirodenafil dihydrochloride | 862189-96-6 | 99.1% | 604.59 | 1 ML
Mirodenafil dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. It also functions as a glucocorticoid receptor (GR) modulator and activates the Wnt/β-catenin signaling pathway. It is used in research for conditions such as erectile dysfunction (ED), Alzheimer's disease (AD), and systemic sclerosis (SSc).
- Exerts neuroprotective functions by activating the cGMP/PKG/CREB signaling pathway.
- Enhances neuronal survival by protecting mitochondrial membrane potential and inhibiting apoptosis.
- Inhibits GSK-3β signaling, reducing tau phosphorylation and decreasing Aβ production.
- Inhibits transcriptional activity and homodimerization of glucocorticoid receptor.
- Ameliorates dermal fibrosis in SSc mouse models by inhibiting TGF-β signaling pathway.
Medchemexpress LLC MPEP Hydrochloride | 219911-35-0 | 99.82% | 229.70 | 1 ML
MPEP Hydrochloride is a potent, selective, noncompetitive, orally active, and systemically active mGlu5 receptor antagonist with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. It also exhibits anxiolytic- or antidepressant-like effects. Additionally, MPEP Hydrochloride serves as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Potent, selective, noncompetitive mGlu5 receptor antagonist.
- Orally active and systemically active.
- Exhibits anxiolytic- or antidepressant-like effects.
- Functions as a click chemistry reagent due to its Alkyne group, enabling CuAAc reactions with Azide-containing molecules.
Apexbio Technology LLC KN-93 hydrochloride 1956426-56-4 1mg
KN-93 hydrochloride (CAS 1956426-56-4) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase II (CaMK II) binding competitively at the calmodulin site with a reported Ki of 0 37 M and an IC50 of 370 nM In isolated gastric parietal cells KN-93 suppresses acid secretion stimulated by carbachol and histamine with IC50 values of 0 15 M and 0 3 M respectively and inhibits mucin-stimulated aminopyrine uptake (IC50 0 6 M) Additionally KN-93 shows inhibitory activity against H /K -ATPase and directly blocks voltage-gated potassium (Kv) channels by promoting C-type inactivation KN-93 is widely used to probe CaMK II signaling and its downstream physiological effects in cellular and electrophysiological studies
Apexbio Technology LLC Tacrine hydrochloride 1684-40-8 10mM (in 1mL H2O)
Tacrine hydrochloride (CAS 1684-40-8) is a small molecule inhibitor of cholinesterases exhibiting potent inhibitory activity against both acetylcholinesterase (AChE IC 31 nM) and butyrylcholinesterase (BChE IC 25 6 nM) in vitro Additionally it has been shown to inhibit N-methyl-D-aspartate receptors (NMDARs) with an IC of approximately 26 M By modulating both cholinergic and glutamatergic signaling pathways tacrine hydrochloride is frequently employed in studies investigating the molecular mechanisms underlying Alzheimer s disease and exploring potential therapeutic strategies for neurodegenerative disorders
eMolecules 1-Naphthylacetyl Spermine Trihydrochloride | 1049731-36-3 | MFCD01321052 | 250mg
Toronto Research Chemicals | 1-Naphthylacetyl Spermine Trihydrochloride | 250mg | 483425926 | N377800 | | 1049731-36-3 | MFCD01321052 | 479.920 | C22H37Cl3N4O
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC C24:1 dihydro 1-deoxyceramide (m18:0/24:1) | 1246298-60-1 | MFCD22416693 | 99.0% | 634.11 g/mol | C42H83NO2 | 5 MG
C24:1 dihydro 1-deoxyceramide (m18:0/24:1) is a long-chain deoxyceramide provided for research use. Supplied as a white to off-white solid, it is used as a reference standard or reagent in studies of sphingolipid metabolism, lipidomics, and biochemical assays.
- High purity (99.0%).
- White to off-white solid appearance.
- Suitable for lipidomics and sphingolipid research applications.
- Provided with COA, SDS, and data sheet available.
- Offered in small milligram pack sizes for analytical work.
Selleck Chemical LLC Tacrine hydrochloride hydrate S3639-1g
Tacrine (Tetrahydroaminacrine Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants as a respiratory stimulant and in the treatment of Alzheimer s disease and other central nervous system disorders It also acts as a histamine N-methyltransferase inhibitor