Oxazinanes
TARGETMOL CHEMICALS INC ALE-0540 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA as well as signal transduction and biological responses mediated by TrkA receptors. purity: 97%
TARGETMOL CHEMICALS INC BENZOQUINAMIDE HYDROCHLO 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Benzoquinamide hydrochloride (3-carbamoyl-NN-diethyl-1346711b-hexahydro-911-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance. purity: 99%
TARGETMOL CHEMICALS INC PPTN HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PPTN hydrochloride is a potent high-affinity competitive highly selective P2Y14 receptor antagonist (KB 434 pM) but no agonist or antagonist activity at P2Y1 P2Y2 P2Y4 P2Y6 P2Y11 P2Y12 or P2Y13 receptors exhibiting anti-inflammatory and anti-immune effects. purity: 99%
TARGETMOL CHEMICALS INC SELVIGALTIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer. purity: 99%
TARGETMOL CHEMICALS INC PCI-34051 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PCI-34051 is an effective and selective HDAC8 inhibitor (IC50 10 nM). purity: 99%
TARGETMOL CHEMICALS INC KU-57788 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50 14 nM). purity: 99%
TARGETMOL CHEMICALS INC CX-6258 HYDROCHLORIDE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective orally efficacious Pim1/2/3 kinase inhibitor (IC50 5/25/16 nM). purity: 98%
TARGETMOL CHEMICALS INC AGOMELATINE HYDROCHLORID 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Agomelatine hydrochloride (S-20098 hydrochloride) (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1 0.06 nM for HEK-hMT1 0.12 nM for CHO-hMT2 and 0.27 nM for HEK-hMT2 respectively [1]. Agomelatine hydrochloride is a selective antagonist of a 5-HT2C receptor with pKis of 6.4 and 6.2 for native (porcine) and cloned human 5-HT2C receptors respectively [2]. purity: 100%
TARGETMOL CHEMICALS INC HERBACETIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Herbacetin induces apoptosis in HepG2 cells by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. purity: 99%
TARGETMOL CHEMICALS INC SCH-23390 HYDROCHLORIDE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). purity: 99%
TARGETMOL CHEMICALS INC MPTP HYDROCHLORIDE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MPTP hydrochloride (MPTP-hydrochloride) is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. purity: 99%
TARGETMOL CHEMICALS INC BLARCAMESINE HYDROCHLORI 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50 860 nM). purity: 99%
TARGETMOL CHEMICALS INC S-ERSO 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. (S)-ErSO is an inactive dextrorotatory enantiomer of ErSO. purity: 97%
TARGETMOL CHEMICALS INC ROLAPITANT HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rolapitant (SCH619734) hydrochloride is a potent selective long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CYP3A4. Rolapitant hydrochloride shows potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models [1] [2]. purity: 99%
TARGETMOL CHEMICALS INC SRT1720 HYDROCHLORIDE 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5 0.16 uM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s 37 uM/300 uM). purity: 99%