Oxazinanes
TARGETMOL CHEMICALS INC IFN ALPHA-IFNAR-IN-1 HYD 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-(alpha) and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-(alpha) responses by BM-pDCs with IC50 of 2-8 uM. purity: 99%
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 10 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative for research use only, and can be used for bronchiectasis research.
- Chemical formula: C15H10O4
- Molecular weight: 254.24
- Appearance: Solid, off-white to yellow
- Solubility: 100 mg/mL in DMSO
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Related disease areas: Neurological, Eye or Ear Disease, Inflammation or Immune System Disease, Neurodegenerative Disease, Parkinson's Disease
- Signaling pathways: Inflammation/Immunology, Metabolic Enzyme/Protease, Neuronal Signaling, COMT
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 1 ML
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative primarily used for bronchiectasis research. It is intended for research use only and not for medical applications.
- High purity (99.35%)
- Supplied as a 10 mM solution in DMSO
- Appearance: off-white to yellow solid
- Molecular weight: 254.24
- Demonstrates cytotoxicity against human A375 cells with an IC50 of 39 μM
- Demonstrates cytotoxicity against human MRC5 cells with an IC50 of 47 μM
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 10 MG
Bomedemstat (IMG-7289) dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor.
- Increases H3K4 and H3K9 methylation.
- Alters gene expression.
- Shows anti-cancer activities.
- Inhibits cancer cell proliferation.
- Induces apoptosis.
Medchemexpress LLC Flunarizine dihydrochloride | 30484-77-6 | 99.9% | 1 G
Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker and a D2 dopamine receptor antagonist. It exhibits anticonvulsive, antimigraine, and peripheral vasodilator effects.
- Potent dual Na+/Ca2+ channel (T-type) blocker
- D2 dopamine receptor antagonist
- Exhibits anticonvulsive activity
- Exhibits antimigraine activity
- Exhibits peripheral vasodilator effects
Cayman Chemical Y27632 hydrochloride
A potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM); also inhibits PRK2 with an IC50 value of 600 nM
eMolecules 2H-1,4-Benzoxazine, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- | 1155264-46-2 | MFCD18073255 | 1g
Combi-Blocks | 2H-1,4-Benzoxazine, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- | 1g | 117529774 | FF-5591 | 95.000 | 1155264-46-2 | MFCD18073255 | 261.130 | C14H20BNO3
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TARGETMOL CHEMICALS INC SEP-363856 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique non-D2/5-HT2A mechanism of action exerts its antipsychotic-like effects has the potential to treatment of schizophrenia. purity: 99%
Apexbio Technology LLC PJ34 hydrochloride 344458-15-7 10mM (in 1mL DMSO)
PJ34 hydrochloride (CAS 344458-15-7) is a small molecular inhibitor targeting poly(ADP-ribose) polymerase (PARP) an enzyme critical for DNA repair and cellular proliferation In vitro assays demonstrate dose-dependent inhibition of purified PARP activity with an EC50 of approximately 20 nM Unlike other inhibitors such as 3-aminobenzamide (3-AB) PJ34 lacks antioxidant properties and exhibits significantly higher inhibitory potency against PARP Experimental studies have shown PJ34 protects against peroxynitrite-induced cell necrosis (EC50 20 nM) and dose-dependently suppresses proliferation in HepG2 liver cancer cell lines enhancing chemotherapeutic efficacy and conferring neuroprotection in various disease models
Cayman Chemical HA1077 hydrochloride
A potent inhibitor of ROCK2, PRK-2, MSK1, and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively; has been shown to reduce blood vessel constriction, decreases pulmonary arterial pressure, inhibit tumor angiogenesis, and improve insulin signaling in a diabetic rat model; drug forms are marketed for the treatment of pulmonary arterial hypertension and stable angina
![eMolecules Synthonix tert-butyl N-[trans-3-aminocyclohexyl]carbamate 1g 808540754 B24511 609788-04-7 MFCD18632893 214.309 C11H22N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694493.jpg-250.jpg)
eMolecules Synthonix tert-butyl N-[trans-3-aminocyclohexyl]carbamate 1g 808540754 B24511 609788-04-7 MFCD18632893 214.309 C11H22N2O2
Synthonix tert-butyl N-[trans-3-aminocyclohexyl]carbamate 1g 808540754 B24511 609788-04-7 MFCD18632893 214.309 C11H22N2O2
TARGETMOL CHEMICALS INC LEUKADHERIN-1 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen Decreasing leukocyte motility and transendothelial migration; reduces inflammation. purity: 98%
Cayman Chemical Y27632 hydrochloride
A potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM); also inhibits PRK2 with an IC50 value of 600 nM
eMolecules Synthonix - Stock 2-(Tributylstannylmethylsulfanyl)ethanamine 500mg 525924737 T9181 1452829-00-3 MFCD23703162 380.220 C15H35NSSn
Synthonix - Stock 2-(Tributylstannylmethylsulfanyl)ethanamine 500mg 525924737 T9181 1452829-00-3 MFCD23703162 380.220 C15H35NSSn