Oxazinanes
AdipoGen Verapamil hydrochloride
Chemical. CAS 152-11-4. Formula C27H38N2O4 . HCl. MW 491.06. Synthetic Verapamil hydrochloride is an alpha-adrenergic receptor alpha-AR antagonist and calcium channel protein inhibitor that blocks the L-type Ca2 channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr P-glycoprotein. Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models.
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 g/mol | C28H36Cl2FN7O2 | 5 MG
Bomedemstat dihydrochloride is the dihydrochloride salt of bomedemstat, an irreversible lysine-specific demethylase 1 (LSD1) inhibitor supplied for research use. It is provided as a white to light yellow solid intended for biochemical and cell-based studies of epigenetic regulation and oncology-related research. Store sealed, away from moisture at -20°C; stability in solution: -80°C up to 6 months, -20°C up to 1 month.
Selleck Chemical LLC PF-06446846 hydrochloride
PF-06446846 (PF846) Hydrochloride is an orally bioavailable and specific inhibitor of PCSK9 with an IC50 of 0 3 M in Huh7 cells
![Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 99.96% | 120.16 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000405220-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 99.96% | 120.16 | 10 G
2,3-Dihydro-7-azaindole (7-Azaindoline) is a biochemical reagent. It can be used as a biological material or organic compound for life science related research.
- Can be used as a biological material
- Can be used as an organic compound
- Suitable for life science related research
Selleck Chemical LLC Colesevelam Hydrochloride
Colesevelam Hydrochloride is an orally administered non-absorbable polymeric bile-acid-binding agent with a higher affinity for glycocholic acid in vitro
Selleck Chemical LLC Iptacopan Hydrochloride
Iptacopan Hydrochloride is a first-in-class orally administered potent and highly selective factor B inhibitor with an IC50 of 12 nM and a Kd value of 7 9 nM Iptacopan exhibits excellent selectivity over other proteases affording IC50s of 30 M across a panel of 41 human proteases
Selleck Chemical LLC Vernakalant Hydrochloride
Vernakalant (RSD-1235 MK-6621) is a novel frequency-dependent Na channel and early activating K channel blocker that selectively prolongs the atrial refractory period
eMolecules Combi-Blocks Inc. (S)-5-Amino-piperidin-2-one hydrochloride 1g 603145105 QC-5413 96.000 672883-95-3 MFCD03094719 150.610 C5H11ClN2O
Combi-Blocks Inc. (S)-5-Amino-piperidin-2-one hydrochloride 1g 603145105 QC-5413 96.000 672883-95-3 MFCD03094719 150.610 C5H11ClN2O
eMolecules Pharmablock 22-difluoromorpholine hydrochloride 100mg 799220939 PB94086-1 1820647-38-8 MFCD29033956 159.560 C4H8ClF2NO
Pharmablock 22-difluoromorpholine hydrochloride 100mg 799220939 PB94086-1 1820647-38-8 MFCD29033956 159.560 C4H8ClF2NO
Selleck Chemical LLC Vazegepant hydrochloride
Vazegepant hydrochloride (BHV-3500 Zavegepant) is a highly potent selective and structurally unique small molecule antagonist of CGRP receptor It can also be used for the acute treatment of migraine
Selleck Chemical LLC ACHP Hydrochloride-E1278-1MG
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK- inhibitor with an IC50 of 8 5 nM
eMolecules AstaTech (R)-3-(TERT-BUTYLDIMETHYLSILYLOXY) PIPERIDINE 1g 323600113 A10005 95.000 1416807-31-2 MFCD18206135 215.412 C11H25NOSi
AstaTech (R)-3-(TERT-BUTYLDIMETHYLSILYLOXY) PIPERIDINE 1g 323600113 A10005 95.000 1416807-31-2 MFCD18206135 215.412 C11H25NOSi