Oxazinanes
Apexbio Technology LLC AMTB hydrochloride 1mg
AMTB hydrochloride (CAS 926023-82-7) is a selective antagonist of the TRPM8 ion channel effectively inhibiting TRPM8-mediated activation induced by agonists such as icilin with a reported pIC50 of approximately 6 23 In addition to its primary action AMTB hydrochloride also exhibits non-selective inhibitory effects on voltage-gated sodium channels (NaV) This compound is commonly utilized in biomedical research to investigate the role of TRPM8 channel activity alterations in the pathophysiology of bladder overactivity and bladder pain syndrome
eMolecules Octahydro-2h-1,4-benzoxazine | 52769-11-6 | MFCD08273499 | 10g
Combi-Blocks, Inc. | Octahydro-2h-1,4-benzoxazine | 10g | 603135587 | JK-4067 | 95.000 | 52769-11-6 | MFCD08273499 | 141.214 | C8H15NO
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Selleck Chemical LLC Harmine hydrochloride S3817-1g
Harmine (Telepathine) a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A with about 60-fold higher IC50 value for DYRK2 Harmine also inhibits monoamine oxidases (MAOs) PPAR and cdc-like kinases (CLKs) Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM
Medchemexpress LLC 7-Methoxyisoflavone | 1621-56-3 | 250 MG
7-Methoxyisoflavone is an isoflavone derivative that acts as an activator of adenosine monophosphate-activated protein kinase (AMPK). It is suitable for research applications, preventing the serum-induced decrease in AMPK phosphorylation in serum-starved cells treated with 10% FBS.
- Activates adenosine monophosphate-activated protein kinase (AMPK)
- Prevents serum-induced decrease in AMPK phosphorylation
- High purity of 99.47%
- White to off-white solid appearance
- Soluble in DMSO
- Available with in vivo dissolution protocols
Medchemexpress LLC PI-103 hydrochloride | 371935-79-4 | MFCD10687102 | 98.6% | 384.82 g/mol | C19H17ClN4O3 · HCl | 50 MG
PI-103 hydrochloride is a research-grade small molecule inhibitor of phosphatidylinositol 3-kinase (PI3K) and mechanistic target of rapamycin (mTOR). It is used in biochemical and cellular studies to probe PI3K/mTOR signaling and DNA-PK activity, and is supplied as a hydrochloride salt for consistent handling in laboratory assays.
- Dual PI3K and mTOR inhibitor useful for pathway interrogation.
- Potent biochemical activity with low-nanomolar IC50s against key kinases.
- Also inhibits DNA-PK, supporting DNA damage response studies.
- High purity suitable for research applications.
- Available in multiple sizes for screening or scale-up experiments.
Selleck Chemical LLC (S.R.S)-AHPC hydrochloride S1062-1g
(S R S)-AHPC hydrochloride (VH032-NH2 VHL ligand 1) is the VH032-based VHL ligand that is applicable to the recruitment of the von Hippel-Lindau (VHL) protein (S R S)-AHPC hydrochloride can be connected to the ligand for protein by a linker to form PROTACs
eMolecules ChemScene / 7-Amino-2-methyl-14-dihydroisoquinolin-3(2h)-one / 100mg / 632828890 / CS-0197568 / 0.000 / 1363337-85-2 / MFCD22208581 / 176.219 / C10H12N2O
ChemScene / 7-Amino-2-methyl-14-dihydroisoquinolin-3(2h)-one / 100mg / 632828890 / CS-0197568 / 0.000 / 1363337-85-2 / MFCD22208581 / 176.219 / C10H12N2O
![eMolecules [2-(2-Furyl)-2-morpholin-4-ylethyl]amine | 876717-86-1 | MFCD07186445 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502186363.JPG-250.jpg)
eMolecules [2-(2-Furyl)-2-morpholin-4-ylethyl]amine | 876717-86-1 | MFCD07186445 | 1g
Combi-Blocks, Inc. | [2-(2-Furyl)-2-morpholin-4-ylethyl]amine | 1g | 603153962 | QZ-4313 | 95.000 | 876717-86-1 | MFCD07186445 | 196.250 | C10H16N2O2
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Medchemexpress LLC Pirenzepine dihydrochloride | 29868-97-1 | 99.8% | 424.32 | 1 ML
Pirenzepine dihydrochloride is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist with poor penetration of the blood-brain barrier. It reduces gastric acid secretion and muscle spasm, and can be used in peptic ulcers research. Pirenzepine dihydrochloride also shows anti-proliferative activity to cancer cells.
- Selective M1 mAChR antagonist
- Poor penetration of the blood-brain barrier
- Reduces gastric acid secretion
- Reduces muscle spasm
- Can be used in peptic ulcers research
- Shows anti-proliferative activity to cancer cells
TARGETMOL CHEMICALS INC Irinotecan hydrochloride trihy
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1. Purity 99.52%
Cayman Chemical SRT 1720 hydrochloride
A selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol; improves insulin sensitivity, lowers plasma, glucose and increases mitochondrial capacity in diet-induced obese and diabetic leptin-deficient ob/ob mice after one week of treatment with an oral dose of 100 mg/kg once daily.