Oxazinanes
Medchemexpress LLC M-PEG12-Br | 1620461-89-3 | C25H51BrO12 | 250 MG
m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Key component in the creation of PROTACs.
- Functions by connecting a ligand for an E3 ubiquitin ligase with a ligand for a target protein.
- Harnesses the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
Medchemexpress LLC m-PEG6-Br | 125562-29-0 | 99.8% | C13H27BrO6 | 250 MG
m-PEG6-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Pure form storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Sigma Aldrich 2-Isopropylcyclopentanone
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Sigma Aldrich 1-benzofuran-5-ylmethylamine
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Sigma Aldrich 5-Nitroindole
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Sigma Aldrich 3-ACETOXY-4-METHOXYCARBONYLPHENYLBORONIC ACID PINACOL ESTER
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Sigma Aldrich 4-Cyanoindole
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Sigma Aldrich 2-Iodobiphenyl
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Sigma Aldrich Pamoic acid
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Sigma Aldrich 2,4-dichloro-1-(2-propynyloxy)benzene
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