Piperazines

Organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions in the ring.

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1,861

Apexbio Technology LLC CP 31398 dihydrochloride 1217195-61-3 1mg

CP 31398 dihydrochloride (CAS 1217195-61-3) is a small molecule that modulates the tumor suppressor protein p53 by stabilizing both wild-type and mutant forms thereby promoting p53-dependent transcriptional activity Through p53 pathway activation CP 31398 dihydrochloride increases p21 expression inhibits G1/S-phase cyclin-dependent kinase complexes and induces apoptosis in multiple cancer cell lines irrespective of p53 mutation status In various models including head and neck squamous cell carcinoma and colon adenocarcinoma it has demonstrated the ability to inhibit cancer cell proliferation and enhance the cytotoxic effects of chemotherapeutic agents Combined administration with celecoxib has been shown to significantly reduce both incidence and multiplicity of colon tumors in preclinical studies supporting its utility in cancer research and therapeutic strategy development

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1,862

eMolecules 23899-32-3 | 2-Methyl-4-(4-pyridyl)thiazole | Oakwood Chemicals | MFCD16658845 | 176.240 | C9H8N2S | 97.000 | Cc1nc(cs1)-c1ccncc1 | 100mg | 480147444

2-Methyl-4-(4-pyridyl)thiazole | Oakwood Chemicals | 23899-32-3 | MFCD16658845 | 176.240 | C9H8N2S | 97.000 | Cc1nc(cs1)-c1ccncc1 | 100mg | 480147444

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1,863

Selleck Chemical LLC Pyrithioxin Dihydrochloride S4730-100mg

Pyrithioxin (Bonifen Encefabol Pyritinol Vitamin B6 disulfide) Dihydrochloride is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate with no vitamin B6 activity