Piperazines

Organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions in the ring.

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1,966 – 1,980 of 4,109 results

1,966

Aobchem AOBCHEM

5001076262 N- 2 2-DIMETHYLPROPYL -2 4-DIF

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1,967

Aobchem AOBCHEM

5001073083 2-CHLORO-N- 1-METHYLETHYL -4-

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1,968

Aobchem AOBCHEM

5001073166 3 5-DIMETHYL-N- 1-METHYLETHYL

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1,969

Aobchem AOBCHEM

5001076488 N- 2-METHOXYETHYL -4-NITROBENZ

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1,970

Aobchem AOBCHEM

5001076953 1-BROMO-4- 1 2-DIMETHYLPROPYL

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1,971

Apexbio Technology LLC E-4031 dihydrochloride 113559-13-0 10mg

E-4031 dihydrochloride (CAS 113559-13-0) is a methanesulfonanilide compound classified as a class III antiarrhythmic agent It selectively inhibits ether- -go-go-related gene (ERG) family potassium channels including hERG (Kv11 1) with an IC50 of 29 nM and demonstrates binding affinities of 99 116 and 193 nM for ERG1 ERG2 and ERG3 respectively By blocking these voltage-gated K channels E-4031 dihydrochloride extends cardiac action potential duration and modulates inwardly rectifying potassium currents in myocardial and gastrointestinal cells This molecule is widely used to study ERG channel physiology arrhythmogenesis and pharmacological rescue of mutant hERG in long QT syndrome type 2