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Filtered Search Results
Apexbio Technology LLC Y-39983 dihydrochloride 173897-44-4 2mg
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Y-39983 dihydrochloride (CAS 173897-44-4) is a selective inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK) exhibiting an IC50 of 3 6 nM for ROCK inhibition It demonstrates substantially reduced inhibitory activity against protein kinase C (PKC IC50 0 42 M) and Ca2 /calmodulin-dependent protein kinase II (CaMKII IC50 0 81 M) In ex vivo studies Y-39983 dihydrochloride induces relaxation of pre-contracted rabbit ciliary arteries and has been shown to increase optic nerve head blood flow Furthermore dose-dependent reductions in intraocular pressure have been observed in both rabbit and monkey models These properties suggest its value for research on ROCK-related signaling in ocular physiology and vascular tone regulation
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Selleck Chemical LLC Sardomozide dihydrochloride
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Sardomozide dihydrochloride (CGP 48664A) is a potent inhibitor of S-adenosylmethionine decarboxylase (SAMDC) with an IC50 of 5 nM It is also a potent inhibitor of polyamine oxidase and exhibits with broad spectrum antiproliferative and antitumor activity
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Apexbio Technology LLC IT1t dihydrochloride 1092776-63-0 50mg
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IT1t dihydrochloride (CAS 1092776-63-0) is a small-molecule antagonist targeting the chemokine receptor CXCR4 It is designed to inhibit CXCR4-mediated signaling by disrupting interactions with its natural ligand CXCL12 as well as the HIV envelope protein gp120 thereby interfering with cellular chemotaxis and viral entry mechanisms IT1t dihydrochloride exerts its biological activity primarily by antagonizing CXCR4 to inhibit receptor-mediated Ca2 mobilization and virus attachment In in vitro assays IT1t dihydrochloride demonstrates potent inhibition with IC50 values of approximately 8 nM in human CXCR4 receptor binding assays 1 1 nM in Ca2 mobilization assays and 7 nM in HIV attachment assays Based on these pharmacological properties IT1t dihydrochloride holds research potential in CXCR4-related signaling and HIV entry studies
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Medchemexpress LLC Benzyl-piperazine-co-benzothiazole-4-methylpiperidine | 906258-48-8 | 99.0% | 434.60 | C25H30N4OS | 5 MG
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Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine is a small-molecule research reagent reported to alter lifespan in eukaryotic organisms. It is supplied as a high-purity solid intended for laboratory research use only and is typically handled and stored under standard compound management conditions.
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Medchemexpress LLC 2-(Ethoxycarbonyl)-3-methylbutanoic acid | 15112-52-4 | C8H14O4 | 1 G
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2-(Ethoxycarbonyl)-3-methylbutanoic acid is a drug intermediate used for the synthesis of various active compounds. It is for research use only and not sold to patients.
- Used for synthesis of various active compounds.
- For research use only.
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Selleck Chemical LLC JTE-607 Dihydrochloride
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JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing JTE-607 inhibits tumor necrosis factor (TNF)-alpha interleukin (IL)-1beta IL-6 IL-8 and IL-10 from LPS-stimulated human PBMCs with IC50 values of 11 nM 5 9 nM 8 8 nM 7 3 nM and 9 1 nM respectively
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![eMolecules 71766-33-1 | 2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502142057.JPG-250.jpg)
eMolecules 71766-33-1 | 2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502
2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | 71766-33-1 | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502
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eMolecules 192130-34-0 | 4-N-(2-Aminoethyl)-1-N-Boc-piperazine | Combi-Blocks | MFCD02683049 | 229.324 | C11H23N3O2 | 98.000 | CC(C)(C)OC(=O)N1CCN(CCN)CC1 | 25g | 232307048
4-N-(2-Aminoethyl)-1-N-Boc-piperazine | Combi-Blocks | 192130-34-0 | MFCD02683049 | 229.324 | C11H23N3O2 | 98.000 | CC(C)(C)OC(=O)N1CCN(CCN)CC1 | 25g | 232307048
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Medchemexpress LLC N-tert-Butoxycarbonyl-D-tyrosine methyl ester | 76757-90-9 | ≥98.0% | 295.33 | 100 G
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N-tert-Butoxycarbonyl-D-tyrosine methyl ester is a tyrosine derivative. Amino acids and their derivatives are used commercially as ergogenic supplements due to their influence on anabolic hormone secretion, fuel supply during exercise, mental performance during stress, and prevention of exercise-induced muscle damage. They are recognized for their beneficial effects as ergogenic dietary substances.
- Tyrosine derivative
- Can be used as an ergogenic supplement
- Influences anabolic hormone secretion
- Supplies fuel during exercise
- Enhances mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
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eMolecules 886-60-2 | 1-Phenyl-3-(2-pyridyl)-2-thiourea | Oakwood Chemical | MFCD00023430 | 229.300 | C12H11N3S | 0.000 | S=C(Nc1ccccc1)Nc1ccccn1 | 1g | 537677616
1-Phenyl-3-(2-pyridyl)-2-thiourea | Oakwood Chemical | 886-60-2 | MFCD00023430 | 229.300 | C12H11N3S | 0.000 | S=C(Nc1ccccc1)Nc1ccccn1 | 1g | 537677616
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Aobchem AOBCHEM
5000944082 4- 2-METHOXYETHYL - - 1-METHYL
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Aobchem AOBCHEM
5000946098 2- 1-METHYL-4-PIPERIDINYL OXY
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Aobchem AOBCHEM
5000940879 1- 5- 1 1-DIMETHYLPROPYL -2-ME
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Aobchem 5-Bromo-N-(2-methoxyethyl)-2-thiophenesulfonamide | ≥95% | CAS 899232-94-1 | C7H10BrNO3S2 | 500mg
5-Bromo-N-(2-methoxyethyl)-2-thiophenesulfonamide | ≥95% | CAS 899232-94-1 | C7H10BrNO3S2 | 500mg
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Aobchem 4-(2-Hydroxyethoxy)-3-methoxybenzaldehyde | ≥97% | CAS 64673-04-7 | C10H12O4 | 1g
4-(2-Hydroxyethoxy)-3-methoxybenzaldehyde | ≥97% | CAS 64673-04-7 | C10H12O4 | 1g
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