Piperazines
eMolecules N-(2,6-Dimethylphenyl)-6-methoxypyridine-2-carboxamide | Combi-Blocks, Inc. |256.305 | C15H16N2O2 | 98.000 | COc1cccc(n1)C(=O)Nc1c(C)cccc1C | 1g | 893975016
N-(2,6-Dimethylphenyl)-6-methoxypyridine-2-carboxamide | Combi-Blocks, Inc. |256.305 | C15H16N2O2 | 98.000 | COc1cccc(n1)C(=O)Nc1c(C)cccc1C | 1g | 893975016
eMolecules piperazine DiHCl | 142-64-3 | MFCD00012754 | 5g
Combi-Blocks, Inc. | piperazine DiHCl | 5g | 569294244 | AM-1897 | 95.000 | 142-64-3 | MFCD00012754 | 159.050 | C4H12Cl2N2
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eMolecules Building Block Tool
Medchemexpress LLC Thalidomide-Piperazine-Piperidine hydrochloride | 2599846-44-1 | 98.4% | 461.94 | 100 MG
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. For research use only, this product is not sold to patients.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Apexbio Technology LLC Annexin V-APC/PI Apoptosis Kit 100tests
Annexin V is a Ca2 -dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS is localized on the inner leaflet of the cell membrane lipid bilayer During the early stages of apoptosis PS translocates from the inner leaflet to the outer surface of the cell membrane exposing it to the extracellular environment Due to Annexin V s high affinity for PS fluorescently labeled Annexin V (APC) can be used as a probe in combination with flow cytometry or fluorescence microscopy for detecting apoptosis and the staining process requires only 10-20 minutes Additionally this kit can be paired with the nuclear dye propidium iodide (PI) PI specifically binds to double-stranded DNA emitting red fluorescence upon binding but it cannot normally permeate intact cell membranes However PI can penetrate compromised cellular membranes in late-stage apoptotic and dead cells staining nuclei Therefore combined staining with Annexin V-APC and PI allows
eMolecules 1177327-68-2 | 2-(4-Bromo-2-thienyl)piperidine hydrochloride | Combi-Blocks | MFCD08277195 | 282.620 | C9H13BrClNS | 95.000 | Cl.Brc1csc(c1)C1CCCCN1 | 1g | 205401576
2-(4-Bromo-2-thienyl)piperidine hydrochloride | Combi-Blocks | 1177327-68-2 | MFCD08277195 | 282.620 | C9H13BrClNS | 95.000 | Cl.Brc1csc(c1)C1CCCCN1 | 1g | 205401576
![eMolecules 250383-80-3 | [2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502199471.JPG-250.jpg)
eMolecules 250383-80-3 | [2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996
[2-(4-METHYL-1-PIPERAZINYL)PHENYL]BORONIC ACID | AstaTech | 250383-80-3 | MFCD22570819 | 220.080 | C11H17BN2O2 | 95.000 | CN1CCN(CC1)c1ccccc1B(O)O | 1g | 587288996
Medchemexpress LLC 4-Chloro-DL-phenylalanine methyl ester hydrochloride | 14173-40-1 | MFCD00012530 | 99.9% | 250.12 | C10H13Cl2NO2 | 5 G
PCPA methyl ester hydrochloride is the hydrochloride salt of 4-chloro-DL-phenylalanine methyl ester provided for research use. It acts as a tryptophan hydroxylase inhibitor and is used in neurochemical and pharmacological studies to reduce central serotonin (5-HT) levels. The compound is supplied as a high-purity solid suitable for biochemical and in vivo experiments.
- High purity suitable for research applications.
- Inhibits tryptophan hydroxylase to reduce serotonin synthesis.
- Crosses the blood-brain barrier for central nervous system studies.
- Provided as a stable hydrochloride salt for reproducible dosing.
- Available in multiple lab-scale pack sizes for experimental flexibility.
eMolecules 55091-60-6 | Vinylcyclopropylphenylcarbinol | Oakwood Chemical174.243 | C12H14O | 90.000 | OC(C=C)(C1CC1)c1ccccc1 | 250mg | 537709937
Vinylcyclopropylphenylcarbinol | Oakwood Chemical | 55091-60-6174.243 | C12H14O | 90.000 | OC(C=C)(C1CC1)c1ccccc1 | 250mg | 537709937
eMolecules 885275-22-9 | 1-(2-Bromo-phenyl)-piperazin-2-one | J & W PharmLab, LLC | MFCD06658379 | 255.115 | C10H11BrN2O | 96.000 | Brc1ccccc1N1CCNCC1=O | 5g | 249987033
1-(2-Bromo-phenyl)-piperazin-2-one | J & W PharmLab, LLC | 885275-22-9 | MFCD06658379 | 255.115 | C10H11BrN2O | 96.000 | Brc1ccccc1N1CCNCC1=O | 5g | 249987033
Apexbio Technology LLC AO/PI Double Staining Kit 500T
The AO/PI Double Staining Kit is a reagent kit enabling rapid detection of cell viability This kit provides two nuclear dyes Acridine Orange (AO) and Propidium Iodide (PI) AO can penetrate intact cell membranes and stain viable cells green During apoptosis chromosomes become condensed or fragmented into differently sized segments In this scenario AO stains apoptotic cells densely with yellow-green fluorescence or as yellow-green fragments The other nuclear dye PI cannot pass through intact cell membranes therefore it does not stain viable or apoptotic cells in red but stains cells with compromised membranes (e g necrotic cells) When using these two dyes in combination viable cells exhibit green fluorescence apoptotic cells show dense varied-size yellow-green or orange fluorescence and necrotic cells exhibit strong red fluorescence
Medchemexpress LLC 5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester dihydrochloride hydrate | 1422956-31-7 | C15H22Cl2N2O4 | 100 MG
5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester dihydrochloride hydrate is a chemical compound classified as a drug intermediate. It is designed for laboratory research purposes, specifically for the synthesis of various active compounds. This product is for research use only and has not been fully validated for medical applications.
- Used as a drug intermediate
- Facilitates the synthesis of various active compounds
- Intended for laboratory research only
- Not validated for medical applications
Cayman Chemical BafIlomycIn A1 1mg
A bacterial metabolite with diverse biological activities; an inhibitor of V-ATPases (Ki = 0.5 nM in N. crassa vacuolar membranes); >1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and H+-ATPases); inhibits autophagosome maturation and protein degradation in H-4-II-E cells at 100 nM; inhibits chloroquine-induced apoptosis in primary CGNs; reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 and Huh7 cells, as well as HEK293T cells expressing human ACE2, at 100 nM; reduces lung RNA copy numbers and viral pneumonia in ACE2 transgenic mice infected with SARS-CoV-2 at 0.1 mg/kg
Medchemexpress LLC Diethylcarbamazine citrate | 1642-54-2 | 391.42 | 500 MG
Diethylcarbamazine citrate (Standard) is the analytical standard of Diethylcarbamazine (citrate), intended for research and analytical applications. It is an orally active anthropoidal compound that inhibits arachidonic acid metabolism of filaria microfilaria, exhibiting anti-inflammatory and antiparasitic activity. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments.
- Orally active anthropoidal compound
- Inhibitor of arachidonic acid metabolism of filaria microfilaria
- Exhibits anti-inflammatory and antiparasitic activity
- Used as an analytical standard and reference standard assay
- Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Selleck Chemical LLC Diethylcarbamazine citrate S4564-500mg
Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements