Piperazines
![eMolecules 132834-58-3 | 1-[5-(Trifluoromethyl)pyrid-2-yl]piperazine | Chem-Impex | MFCD00114708 | 231.222 | C10H12F3N3 | 99.000 | FC(F)(F)c1ccc(nc1)N1CCNCC1 | 1g | 112749564](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-112749564.PNG-250.jpg)
eMolecules 132834-58-3 | 1-[5-(Trifluoromethyl)pyrid-2-yl]piperazine | Chem-Impex | MFCD00114708 | 231.222 | C10H12F3N3 | 99.000 | FC(F)(F)c1ccc(nc1)N1CCNCC1 | 1g | 112749564
1-[5-(Trifluoromethyl)pyrid-2-yl]piperazine | Chem-Impex | 132834-58-3 | MFCD00114708 | 231.222 | C10H12F3N3 | 99.000 | FC(F)(F)c1ccc(nc1)N1CCNCC1 | 1g | 112749564
eMolecules 22996-17-4 | (4-Amino-2-nitrophenyl)methanol | MFCD01664412 | 250mg
Ambeed | (4-Mercaptophenyl)methanol | 250mg | 589942955 | A164284 | 53339-53-0 | MFCD00041529 | 140.200 | C7H8OS
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eMolecules 933760-08-8 | 4-Amino-1-(3-pyridyl)piperidine | Combi-Blocks | MFCD09928096 | 177.251 | C10H15N3 | 95.000 | NC1CCN(CC1)c1cccnc1 | 1g | 232337424
4-Amino-1-(3-pyridyl)piperidine | Combi-Blocks | 933760-08-8 | MFCD09928096 | 177.251 | C10H15N3 | 95.000 | NC1CCN(CC1)c1cccnc1 | 1g | 232337424
Apexbio Technology LLC Annexin V-FITC/PI Apoptosis Kit 20 assays
Annexin V is a Ca2 -dependent phospholipid-binding protein which specifically binds phosphatidylserine (PS) Under normal conditions PS resides on the inner leaflet of the cell membrane lipid bilayer However during early apoptosis PS flips from the inner to the outer surface of the cell membrane exposing itself to the extracellular environment Annexin V exhibits high affinity for PS and can be labeled with fluorescein isothiocyanate (FITC) FITC-labeled Annexin V serves as a fluorescent probe allowing detection of apoptotic cells by flow cytometry or fluorescence microscopy The staining procedure only takes 10 20 minutes Propidium iodide (PI) binds specifically with double-stranded DNA and emits red fluorescence Normally PI cannot penetrate intact cell membranes However in late apoptotic and dead cells PI can enter through compromised membranes and stain the nuclei When Annexin V-FITC and PI staining are performed simultaneously cells at different stages of apoptos
Medchemexpress LLC N-Methylpiperazine-d4 | 343864-02-8 | 99.4% | C5H8D4N2 | 50 MG
N-Methylpiperazine-d4 is the deuterium labeled N-Methylpiperazine. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. This product is intended for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC PI-103 Hydrochloride 371935-79-4 5mg
PI-103 Hydrochloride (CAS 371935-79-4) is a dual inhibitor targeting class I phosphatidylinositide 3-kinases (PI3K) and mammalian target of rapamycin (mTOR) It selectively inhibits PI3K isoforms p110 p110 p110 and mTOR with reported IC50 values of 0 002 M 0 003 M 0 003 M and 0 030 M respectively PI-103 effectively blocks the PI3K/Akt/mTOR pathway which is centrally involved in cell proliferation and survival signaling and is frequently dysregulated in cancer In various cellular models including leukemia hepatocellular carcinoma glioblastoma and neuroblastoma PI-103 suppresses pathway activation and inhibits cell proliferation It is widely used for investigating PI3K/Akt/mTOR signaling in oncology research
eMolecules 1227068-37-2 | 1,1,1-trifluoro-2-(4-piperidyl)propan-2-ol | MFCD17977193 | 1g
ChemScene | 5-Acetylnicotinonitrile | 100mg | 632303335 | CS-0160622 | 135450-74-7 | MFCD09263918 | 146.149 | C8H6N2O
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![Medchemexpress LLC 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin | 955977-50-1 | 99.0% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231469.png-250.jpg)
Medchemexpress LLC 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin | 955977-50-1 | 99.0% | 25 MG
PI-3065 is a selective small-molecule inhibitor of PI3K p110δ used as a research tool for biochemical and cellular studies. It displays low-nanomolar potency against p110δ and substantially reduced activity against other class I PI3K isoforms.
- Selective p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM).
- Reduced activity against p110α (IC50 910 nM), p110β (IC50 600 nM), and p110γ (IC50 >10,000 nM).
- Molecular formula C27H31FN6OS and molecular weight 506.64 g/mol.
- High reported purity (~98.97%).
- Soluble in DMSO (25 mg/mL; 49.34 mM).
- Store powder at -20°C for long-term storage or 4°C for short-term storage.
- Intended for research use in biochemical assays and cell-based PI3Kδ signaling studies.
Medchemexpress LLC 1-(Chlorocarbonyl)piperidine-d10 | 1219803-31-2 | 98.2% | 157.66 | 50 MG
1-(Chlorocarbonyl)piperidine-d10 is the deuterium labeled 1-(Chlorocarbonyl)piperidine. This compound is intended for research purposes only and is not for patient use. It can serve as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration is notable for its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs
![eMolecules 917900-37-9 | [1-(dimethylsulfamoyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid | MFCD18427616 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502159190.JPG-250.jpg)
eMolecules 917900-37-9 | [1-(dimethylsulfamoyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid | MFCD18427616 | 1g
Pharmablock - Stock | [1-(dimethylsulfamoyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid | 1g | 476475079 | PBXA1696 | 917900-37-9 | MFCD18427616 | 287.020 | C6H9BF3N3O4S
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Medchemexpress LLC 1-methylpiperazine-2,2,3,3,5,5,6,6-d8 | 917358-65-7 | MFCD03428101 | 98.2% | 108.21 g·mol⁻¹ | C5H4D8N2 | 10 MG
1-Methylpiperazine-2,2,3,3,5,5,6,6-d8 is a deuterium-labeled analogue of 1-methylpiperazine intended for research use. It serves as a stable isotopic tracer and internal standard for analytical and quantitative workflows, including mass spectrometry and NMR. This product is supplied for laboratory research and is not for human or clinical use.
- Deuterium-labeled compound for isotopic tracing.
- High chemical purity suitable for analytical workflows.
- Compatible with mass spectrometry and NMR analyses.
- Useful as an internal standard and tracer in quantitative assays.
- Stable, non-radioactive isotope label for reproducible results.
Medchemexpress LLC PI-55 | 1122579-42-3 | 98.9% | C13H13N5O | 25 MG
PI-55 is a specific cytokinin receptor inhibitor structurally related to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3, inhibiting cytokinin-induced haustorium formation and increasing parasite aggressiveness.
- Specific cytokinin receptor inhibitor
- Competitively inhibits BAP binding
- Targets Arabidopsis-specific receptors CRE1/AHK4 and AHK3
- Inhibits cytokinin-induced haustorium formation
- Increases parasite aggressiveness
- Appears as an off-white to light yellow solid
Medchemexpress LLC 2-(1-Piperazinyl)pyrimidine | 20980-22-7 | 164.21 | 1 ML
2-(1-Piperazinyl)pyrimidine is a chemical compound that serves as the major metabolite of Tandospirone. This endogenous metabolite is utilized in various research applications.
- Functions as the major metabolite of Tandospirone.
- Identified as an endogenous metabolite.
- Applicable for in vitro studies, with solubility in DMSO.
- Applicable for in vivo studies, with specific dissolution protocols.
![eMolecules 166249-84-9 | trans-1-Cbz-4-methyl-piperidine-2-carboxylic acid | J & W PharmLab LLC554.640 | C30H38N2O8 | 98.000 | C[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)OCc1ccccc1.C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)OCc1ccccc1 | 1g | 553408968](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502147866.JPG-250.jpg)
eMolecules 166249-84-9 | trans-1-Cbz-4-methyl-piperidine-2-carboxylic acid | J & W PharmLab LLC554.640 | C30H38N2O8 | 98.000 | C[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)OCc1ccccc1.C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)OCc1ccccc1 | 1g | 553408968
trans-1-Cbz-4-methyl-piperidine-2-carboxylic acid | J & W PharmLab LLC | 166249-84-9554.640 | C30H38N2O8 | 98.000 | C[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)OCc1ccccc1.C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)OCc1ccccc1 | 1g | 553408968