Piperazines

Organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions in the ring.

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3,646 – 3,660 of 4,124 results

3,646

Frontier Specialty Chemicals 1G 4- 4-(N-BOC)PIPERAZIN-1-YL

4-[4-(N-Boc)piperazin-1-yl]phenylboronic acid pinacol ester; CAS No: 470478-90-1

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3,647

Apexbio Technology LLC CP 31398 dihydrochloride 1217195-61-3 10mg

CP 31398 dihydrochloride (CAS 1217195-61-3) is a small molecule that modulates the tumor suppressor protein p53 by stabilizing both wild-type and mutant forms thereby promoting p53-dependent transcriptional activity Through p53 pathway activation CP 31398 dihydrochloride increases p21 expression inhibits G1/S-phase cyclin-dependent kinase complexes and induces apoptosis in multiple cancer cell lines irrespective of p53 mutation status In various models including head and neck squamous cell carcinoma and colon adenocarcinoma it has demonstrated the ability to inhibit cancer cell proliferation and enhance the cytotoxic effects of chemotherapeutic agents Combined administration with celecoxib has been shown to significantly reduce both incidence and multiplicity of colon tumors in preclinical studies supporting its utility in cancer research and therapeutic strategy development

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3,648

Apexbio Technology LLC TPT-260 Dihydrochloride 2076-91-7 100mg

TPT-260 Dihydrochloride is a thiophene thiourea derivative primarily used as a molecular probe to investigate biochemical pathways in cell signaling and enzyme function TPT-260 Dihydrochloride modulates biological processes via interaction with specific cellular or enzymatic targets such as kinase signaling pathways ion channels or protein-protein interfaces In biomedical research it is utilized for assay development elucidation of potential therapeutic targets and structure-activity relationship studies involving thiourea derivatives and thiophene-containing bioactive compounds Based on these properties TPT-260 Dihydrochloride holds research potential in the study of cell signaling enzyme function and drug discovery