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Filtered Search Results
Selleck Chemical LLC XE991 dihydrochloride S2967-25mg
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XE 991 (LS190926) dihydrochloride is a blocker of Kv7 (KCNQ) channels that potently inhibits KCNQ1 (Kv7 1) KCNQ2 (Kv7 2) KCNQ2 KCNQ3 (Kv7 3) channel and M-current with IC50 of 0 75 M 0 71 M 0 6 M and 0 98 M respectively
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C(O)=O | 1g | 812069970](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471246.jpg-250.jpg)
eMolecules 63039-48-5 | (S)-2-((tert-butoxycarbonyl)amino)pent-4-ynoic acid | Abosyn Chemicals Inc. | MFCD01320855 | 213.233 | C10H15NO4 | 0.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 1g | 812069970
(S)-2-((tert-butoxycarbonyl)amino)pent-4-ynoic acid | Abosyn Chemicals Inc. | 63039-48-5 | MFCD01320855 | 213.233 | C10H15NO4 | 0.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 1g | 812069970
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Apexbio Technology LLC Veliparib dihydrochloride 912445-05-7 10mg
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Veliparib dihydrochloride (CAS 912445-05-7) is a selective inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 enzymes responsible for DNA repair processes frequently upregulated in various cancers Veliparib inhibits PARP1 and PARP2 with K(i) values of 5 2 and 2 9 nmol/L respectively In colon cancer cell lines (HCT-116 HT-29) veliparib enhances DNA damage and induces G2/M arrest when combined with SN38 or oxaliplatin In preclinical murine melanoma (B16F10) breast cancer (MX-1) and colon cancer (HCT-116) xenografts combination therapy with DNA-damaging agents shows improved antitumor effects
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Selleck Chemical LLC Sardomozide dihydrochloride
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Sardomozide dihydrochloride (CGP 48664A) is a potent inhibitor of S-adenosylmethionine decarboxylase (SAMDC) with an IC50 of 5 nM It is also a potent inhibitor of polyamine oxidase and exhibits with broad spectrum antiproliferative and antitumor activity
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Apexbio Technology LLC ML 120B dihydrochloride 783348-36-7 (free base) 10mg
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ML 120B dihydrochloride is a selective agonist targeting the G-protein-coupled receptor 40 (GPR40) also known as free fatty acid receptor 1 (FFAR1) It is designed to activate GPR40 thereby modulating downstream signal transduction pathways that regulate glucose-stimulated insulin secretion in pancreatic -cells ML 120B dihydrochloride exerts its biological activity primarily through specific engagement of GPR40-mediated pathways Based on these pharmacological properties ML 120B dihydrochloride holds research potential in investigating mechanisms underlying glucose-dependent insulin secretion and in the development of therapeutic strategies for diabetes and related metabolic disorders
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![Alkali Scientific Putrescine Dihydrochloride [1,4 Diaminobutane], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661300.jpg-250.jpg)
Alkali Scientific Putrescine Dihydrochloride [1,4 Diaminobutane], 1 G
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Putrescine Dihydrochloride is a high-purity diamine compound used in cell culture applications to enhance cellular growth and proliferation. It is a key component in the synthesis of polyamines, which are vital for cell division and function. The 1g quantity is ideal for small-scale laboratory experiments that require precise amounts of the compound for enhancing cell culture conditions. Putrescine is used in research on cell signaling, gene expression, and molecular biology, particularly in studies involving cancer, cell growth, and aging. It is commonly employed in laboratories focusing on cellular metabolism and the effects of polyamines in biological systems.
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eMolecules AstaTech / 1-ACETYL-4-METHYLPIPERAZINE HCL / 0.25g / 213340351 / AB1017 / 95.000 / 144205-68-5 / MFCD00673862 / 178.660 / C7H15ClN2O
AstaTech / 1-ACETYL-4-METHYLPIPERAZINE HCL / 0.25g / 213340351 / AB1017 / 95.000 / 144205-68-5 / MFCD00673862 / 178.660 / C7H15ClN2O
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eMolecules 2-(4-Pyridyl)-4-(4-hydroxyphenyl)thiazole | 1518549-00-2 | MFCD28166228 | 5g
Oakwood Chemical | 2-(4-Pyridyl)-4-(4-hydroxyphenyl)thiazole | 5g | 537706259 | 098249 | | 1518549-00-2 | MFCD28166228 | 254.310 | C14H10N2OS
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eMolecules 57260-71-6 | 1-Boc-piperazine | Chem-Impex | MFCD00075265 | 186.255 | C9H18N2O2 | 99.000 | CC(C)(C)OC(=O)N1CCNCC1 | 1kg | 386904166
1-Boc-piperazine | Chem-Impex | 57260-71-6 | MFCD00075265 | 186.255 | C9H18N2O2 | 99.000 | CC(C)(C)OC(=O)N1CCNCC1 | 1kg | 386904166
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Selleck Chemical LLC Alexidine dihydrochloride-5MG
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Alexidine dihydrochloride a dibiguanide compound is an effective and selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1) with an IC50 of 1 08 M in vitro It has the potential to treat type II diabetes
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Accela Chembio Inc 1-boc-4-(2-aminophenyl)piperazine | 25g | 170017-74-0 | MFCD04115046 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
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1-boc-4-(2-aminophenyl)piperazine | 25g | 170017-74-0 | MFCD04115046 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
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Medchemexpress LLC 2-(1-methylethyl)phenyl diphenyl phosphate | 64532-94-1 | MFCD00870203 | 368.36 | C21H21O4P | 25 MG
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2-(1-Methylethyl)phenyl diphenyl phosphate is an aryl diphenyl phosphate compound primarily used as a flame retardant in research and material testing. It is an aromatic phosphate ester with CAS number 64532-94-1, molecular formula C21H21O4P, and molecular weight 368.36.
- Aryl diphenyl phosphate used as a flame retardant.
- CAS number 64532-94-1 for unambiguous identification.
- Molecular formula C21H21O4P; molecular weight 368.36.
- Suitable for analytical and research applications at small sample sizes.
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eMolecules 885270-31-5 | 1-((benzyloxy)carbonyl)-3-((tert-butoxycarbonyl)amino)piperidine-3-carboxylic acid | Advanced ChemBlocks | MFCD04114485 | 378.425 | C19H26N2O6 | 97.000 | CC(C)(C)OC(=O)NC1(CCCN(C1)C(=O)OCc1ccccc1)C(O)=O | 250mg | 718021672
1-((benzyloxy)carbonyl)-3-((tert-butoxycarbonyl)amino)piperidine-3-carboxylic acid | Advanced ChemBlocks | 885270-31-5 | MFCD04114485 | 378.425 | C19H26N2O6 | 97.000 | CC(C)(C)OC(=O)NC1(CCCN(C1)C(=O)OCc1ccccc1)C(O)=O | 250mg | 718021672
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eMolecules 110-85-0 | Piperazine | Apollo Scientific - Building Blocks | MFCD00005953 | 86.138 | C4H10N2 | 97.000 | C1CNCCN1 | 100g | 331052671
Piperazine | Apollo Scientific - Building Blocks | 110-85-0 | MFCD00005953 | 86.138 | C4H10N2 | 97.000 | C1CNCCN1 | 100g | 331052671
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Apexbio Technology LLC L-NIO dihydrochloride 159190-44-0 10mg
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L-NIO dihydrochloride (CAS 159190-44-0) is a potent inhibitor of nitric oxide synthase (NOS) targeting inducible (iNOS) endothelial (eNOS) and neuronal (nNOS) isoforms with an IC50 of 65 M By blocking NOS activity L-NIO reduces nitric oxide (NO) production in activated macrophages and neutrophils which can influence both tumor cell cytotoxicity and inflammatory responses In vitro and in vivo studies demonstrate that L-NIO modulates vascular responses preventing immune complex-induced vasculitis and counteracting hypotensive effects triggered by acetylcholine and bradykinin This compound is widely utilized to investigate the role of NO in inflammation vascular regulation and immune-mediated tissue injury
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