Piperazines

Selleck Chemical LLC HA-100 dihydrochloride S2964-5mg

HA-100 dihydrochloride is an inhibitor of cGMP-dependent protein kinase (PKG) cAMP-dependent protein kinase (PKA) protein kinase C (PKC) and MLC-kinase with IC50 of 4 M 8 M 12 M and 240 M respectively

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Medchemexpress LLC Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine | 906258-48-8 | 99.0% | C25H30N4OS | 50 MG

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Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine is a research compound recognized for its capacity to modify the lifespan of eukaryotic organisms. It is supplied as a solid and is strictly for research applications.

• High purity (99.00%) ensures consistent experimental results.
• Exhibits solubility in solvents such as DMSO and DMF, facilitating in vitro research.
• Comprehensive dissolution protocols are provided for in vivo experimentation.

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Selleck Chemical LLC Pramipexole dihydrochloride S5066-25mg

Pramipexole dihydrochloride (SND919) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson s disease (PD) and restless legs syndrome (RLS) with Ki values of 3 9 nM 2 2 nM 0 5 nM and 5 1 nM for D2S receptor D2L receptor D3 receptor and D4 receptor

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Medchemexpress LLC N4-Benzoylcytosine | 26661-13-2 | 99.2% | 215.21 | 100 G

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N4-Benzoylcytosine is a biochemical reagent suitable for life science-related research. This organic compound is intended for research use only and is not sold to patients.

• Can be used as a biological material
• Can be used as an organic compound
• Purity: 99.21%
• Molecular Weight: 215.21
• Formula: C11H9N3O2
• Appearance: Solid
• Color: White to off-white

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eMolecules​ 110-85-0 | Piperazine | Combi-Blocks | MFCD00005953 | 86.138 | C4H10N2 | 98.000 | C1CNCCN1 | 25g | 257645835

Piperazine | Combi-Blocks | 110-85-0 | MFCD00005953 | 86.138 | C4H10N2 | 98.000 | C1CNCCN1 | 25g | 257645835

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Selleck Chemical LLC Piperazine Erastin-E1063-25MG

Piperazine Erastin is an analog of Erastin which can induces ferroptosis in cancer cells an iron-dependent form of nonapoptotic cell death

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Selleck Chemical LLC JTE-607 Dihydrochloride

JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing JTE-607 inhibits tumor necrosis factor (TNF)-alpha interleukin (IL)-1beta IL-6 IL-8 and IL-10 from LPS-stimulated human PBMCs with IC50 values of 11 nM 5 9 nM 8 8 nM 7 3 nM and 9 1 nM respectively

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Apexbio Technology LLC IT1t dihydrochloride 1092776-63-0 100mg

IT1t dihydrochloride (CAS 1092776-63-0) is a small-molecule antagonist targeting the chemokine receptor CXCR4 It is designed to inhibit CXCR4-mediated signaling by disrupting interactions with its natural ligand CXCL12 as well as the HIV envelope protein gp120 thereby interfering with cellular chemotaxis and viral entry mechanisms IT1t dihydrochloride exerts its biological activity primarily by antagonizing CXCR4 to inhibit receptor-mediated Ca2 mobilization and virus attachment In in vitro assays IT1t dihydrochloride demonstrates potent inhibition with IC50 values of approximately 8 nM in human CXCR4 receptor binding assays 1 1 nM in Ca2 mobilization assays and 7 nM in HIV attachment assays Based on these pharmacological properties IT1t dihydrochloride holds research potential in CXCR4-related signaling and HIV entry studies

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eMolecules​ 227783-08-6 | (1S,3R)-3-(ETHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID | AstaTech | MFCD23701519 | 200.234 | C10H16O4 | 95.000 | CCOC(=O)[C@@H]1CCC[C@@H](C1)C(O)=O | 0.25g | 532624357

(1S,3R)-3-(ETHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID | AstaTech | 227783-08-6 | MFCD23701519 | 200.234 | C10H16O4 | 95.000 | CCOC(=O)[C@@H]1CCC[C@@H](C1)C(O)=O | 0.25g | 532624357

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Medchemexpress LLC It1t dihydrochloride | 1092776-63-0 | MFCD22683853 | ≥98.0% | 479.57 g/mol | C21H36Cl2N4S2 | 10 MG

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IT1t dihydrochloride is a small-molecule antagonist of the chemokine receptor CXCR4, used in research to study CXCL12/CXCR4 signaling and ligand binding. It inhibits the CXCL12-CXCR4 interaction with a reported IC50 of about 2.1 nM and is provided as the dihydrochloride salt for improved stability.

• Potent CXCR4 antagonist with IC50 ≈2.1 nM.
• Suitable for receptor binding and functional assays.
• Supplied as the dihydrochloride salt to improve stability.
• Soluble in water (≈50 mg/mL) and in DMSO (≥30 mg/mL).
• Molecular formula C21H36Cl2N4S2; molecular weight 479.57 g/mol.
• High reported purity (≥95%-≥98% depending on supplier).
• Typical research pack size 10 MG.

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Apexbio Technology LLC CP 31398 dihydrochloride 1217195-61-3 10mg

CP 31398 dihydrochloride (CAS 1217195-61-3) is a small molecule that modulates the tumor suppressor protein p53 by stabilizing both wild-type and mutant forms thereby promoting p53-dependent transcriptional activity Through p53 pathway activation CP 31398 dihydrochloride increases p21 expression inhibits G1/S-phase cyclin-dependent kinase complexes and induces apoptosis in multiple cancer cell lines irrespective of p53 mutation status In various models including head and neck squamous cell carcinoma and colon adenocarcinoma it has demonstrated the ability to inhibit cancer cell proliferation and enhance the cytotoxic effects of chemotherapeutic agents Combined administration with celecoxib has been shown to significantly reduce both incidence and multiplicity of colon tumors in preclinical studies supporting its utility in cancer research and therapeutic strategy development

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Apexbio Technology LLC TPT-260 Dihydrochloride 2076-91-7 100mg

TPT-260 Dihydrochloride is a thiophene thiourea derivative primarily used as a molecular probe to investigate biochemical pathways in cell signaling and enzyme function TPT-260 Dihydrochloride modulates biological processes via interaction with specific cellular or enzymatic targets such as kinase signaling pathways ion channels or protein-protein interfaces In biomedical research it is utilized for assay development elucidation of potential therapeutic targets and structure-activity relationship studies involving thiourea derivatives and thiophene-containing bioactive compounds Based on these properties TPT-260 Dihydrochloride holds research potential in the study of cell signaling enzyme function and drug discovery

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Aobchem 3-Chloro-2-[(1-methylethyl)thio]benzenamine | ≥97% | CAS 179104-32-6 | C9H12ClNS | 500mg

3-Chloro-2-[(1-methylethyl)thio]benzenamine | ≥97% | CAS 179104-32-6 | C9H12ClNS | 500mg

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Aobchem 1-[2 4-Bis(1-methylethyl)phenyl]-1-propanone | 95% | CAS 56222-56-1 | C15H22O | 1g

1-[2 4-Bis(1-methylethyl)phenyl]-1-propanone | 95% | CAS 56222-56-1 | C15H22O | 1g

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Aobchem [2-(1-Methylethyl)phenyl]phenylmethanone | 95% | CAS 19103-09-4 | C16H16O | 250mg

[2-(1-Methylethyl)phenyl]phenylmethanone | 95% | CAS 19103-09-4 | C16H16O | 250mg

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