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Filtered Search Results
Selleck Chemical LLC CRT0066101 dihydrochloride
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CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKC /PKC /PKC activity in multiple
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Apexbio Technology LLC Y-39983 dihydrochloride 173897-44-4 2mg
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Y-39983 dihydrochloride (CAS 173897-44-4) is a selective inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK) exhibiting an IC50 of 3 6 nM for ROCK inhibition It demonstrates substantially reduced inhibitory activity against protein kinase C (PKC IC50 0 42 M) and Ca2 /calmodulin-dependent protein kinase II (CaMKII IC50 0 81 M) In ex vivo studies Y-39983 dihydrochloride induces relaxation of pre-contracted rabbit ciliary arteries and has been shown to increase optic nerve head blood flow Furthermore dose-dependent reductions in intraocular pressure have been observed in both rabbit and monkey models These properties suggest its value for research on ROCK-related signaling in ocular physiology and vascular tone regulation
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Medchemexpress LLC Nicotinic acid mononucleotide triethylamine | 99.4% | 100 MG
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Nicotinic acid mononucleotide triethylamine is a crucial intermediate formed from nicotinic acid (NA) during the biosynthesis of NAD+. It acts as a substrate for nicotinamide mononucleotide/nicotinic acid mononucleotide adenylyltransferase, playing a vital role in metabolic pathways.
- Formed from nicotinic acid via nicotinic acid phosphoribosyltransferase
- Substrate for nicotinamide mononucleotide/nicotinic acid mononucleotide adenylyltransferase
- Molecular weight: 506.97
- Formula: C11H14NO9P.1.7C6H15N
- Appearance: Solid
- Color: White to light yellow
- Storage: 4°C, sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month
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Advanced Chemblocks Inc 1-Boc-3-hydroxymethyl-piperazine; 5G; 97%
Chemical Name: 1-Boc-3-hydroxymethyl-piperazine CAS: 301673-16-5 MW: 216.28 MDL Number: MFCD04115304 Category: piperazine Synonym: 1-Boc-3-hydroxymethyl-piperazine
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Apexbio Technology LLC Veliparib dihydrochloride 912445-05-7 5mg
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Veliparib dihydrochloride (CAS 912445-05-7) is a selective inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 enzymes responsible for DNA repair processes frequently upregulated in various cancers Veliparib inhibits PARP1 and PARP2 with K(i) values of 5 2 and 2 9 nmol/L respectively In colon cancer cell lines (HCT-116 HT-29) veliparib enhances DNA damage and induces G2/M arrest when combined with SN38 or oxaliplatin In preclinical murine melanoma (B16F10) breast cancer (MX-1) and colon cancer (HCT-116) xenografts combination therapy with DNA-damaging agents shows improved antitumor effects
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Chem-Impex International, Inc. 1-Z-Piperazine | MFCD00274317 | 25G
1-Z-Piperazine, MFCD00274317, 25G
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Apexbio Technology LLC KX2-391 dihydrochloride 1038395-65-1 50mg
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KX2-391 dihydrochloride (CAS 1038395-65-1) is an orally bioavailable small molecule that inhibits Src tyrosine kinase through selective interaction with the peptide substrate binding site rather than the ATP-binding site By blocking this non-catalytic domain KX2-391 disrupts Src kinase-mediated signaling pathways involved in tumor cell proliferation and metastatic processes Src kinases are frequently upregulated in various malignancies underscoring their importance in cancer biology KX2-391 is widely utilized in preclinical studies investigating Src-driven mechanisms of oncogenesis and tumor progression
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eMolecules 848853-75-8 | 4-(4-BOC-aminophenyl)phenol | Combi-Blocks | MFCD18313051 | 285.343 | C17H19NO3 | 98.000 | CC(C)(C)OC(=O)Nc1ccc(cc1)-c1ccc(O)cc1 | 1g | 117578751
4-(4-BOC-aminophenyl)phenol | Combi-Blocks | 848853-75-8 | MFCD18313051 | 285.343 | C17H19NO3 | 98.000 | CC(C)(C)OC(=O)Nc1ccc(cc1)-c1ccc(O)cc1 | 1g | 117578751
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Medchemexpress LLC 5'-O-DMT-N4-Bz-2'-F-dC | 146954-77-0 | 99.9% | 651.68 | 500 MG
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5'-O-DMT-N4-Bz-2'-F-dC is a nucleoside with protective and modification effects, intended for research use only.
- Offers protective and modification effects
- Intended for research use only
- Purity of 99.85%
- Molecular weight of 651.68
- Available as a white to off-white solid
- Soluble in DMSO
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![eMolecules 138775-03-8 | (S)-4-Cbz-1-Boc-piperazine-2-carboxylic acid | Acrotein ChemBio Inc. | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 625591736](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000163503.jpg-250.jpg)
eMolecules 138775-03-8 | (S)-4-Cbz-1-Boc-piperazine-2-carboxylic acid | Acrotein ChemBio Inc. | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 625591736
(S)-4-Cbz-1-Boc-piperazine-2-carboxylic acid | Acrotein ChemBio Inc. | 138775-03-8 | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 625591736
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![eMolecules 516494-46-5 | 2-tert-Butyl-7-piperazino-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine | Apollo Scientific | MFCD00728816 | 327.355 | C15H20F3N5 | 97.000 | CC(C)(C)c1cc2nc(cc(N3CCNCC3)n2n1)C(F)(F)F | 1g | 562447337](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502153396.JPG-250.jpg)
eMolecules 516494-46-5 | 2-tert-Butyl-7-piperazino-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine | Apollo Scientific | MFCD00728816 | 327.355 | C15H20F3N5 | 97.000 | CC(C)(C)c1cc2nc(cc(N3CCNCC3)n2n1)C(F)(F)F | 1g | 562447337
2-tert-Butyl-7-piperazino-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine | Apollo Scientific | 516494-46-5 | MFCD00728816 | 327.355 | C15H20F3N5 | 97.000 | CC(C)(C)c1cc2nc(cc(N3CCNCC3)n2n1)C(F)(F)F | 1g | 562447337
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Selleck Chemical LLC Sardomozide dihydrochloride
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Sardomozide dihydrochloride (CGP 48664A) is a potent inhibitor of S-adenosylmethionine decarboxylase (SAMDC) with an IC50 of 5 nM It is also a potent inhibitor of polyamine oxidase and exhibits with broad spectrum antiproliferative and antitumor activity
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eMolecules 57260-71-6 | Tert-Butyl 1-Piperazinecarboxylate | AA Blocks LLC | MFCD00075265 | 186.255 | C9H18N2O2 | 0.000 | CC(C)(C)OC(=O)N1CCNCC1 | 500g | 435952193
Tert-Butyl 1-Piperazinecarboxylate | AA Blocks LLC | 57260-71-6 | MFCD00075265 | 186.255 | C9H18N2O2 | 0.000 | CC(C)(C)OC(=O)N1CCNCC1 | 500g | 435952193
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![eMolecules 71766-33-1 | 2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502142057.JPG-250.jpg)
eMolecules 71766-33-1 | 2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502
2-(3-Pyridyl)-7-azabenzimidazole | Oakwood Chemical | 71766-33-1 | MFCD00859119 | 196.213 | C11H8N4 | 99.000 | c1cncc(c1)-c1nc2cccnc2[nH]1 | 1g | 537712502
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eMolecules 110-85-0 | Piperazine | Chem-Impex | MFCD00005953 | 86.138 | C4H10N2 | 99.000 | C1CNCCN1 | 100g | 272385525
Piperazine | Chem-Impex | 110-85-0 | MFCD00005953 | 86.138 | C4H10N2 | 99.000 | C1CNCCN1 | 100g | 272385525
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