Pyrans
Medchemexpress LLC 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)- | 80434-82-8 | 98.5% | 366.45 | 25 UG
20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4. It binds to the BLT1 receptor with high affinity and inhibits LTB4-mediated neutrophil responses, including migration, degranulation, and leukotriene biosynthesis.
- Binds to the BLT1 receptor with high affinity.
- Inhibits LTB4-mediated neutrophil responses.
- It is a human endogenous metabolite.
- Data sheet, COA, SDS, and handling instructions are available.
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3984058 5 6 CARBOXY 2 7 DICHLORO 100MG
Medchemexpress LLC Carboxy-PTIO potassium | 148819-94-7 | 99.0% | 315.39 | 100 MG
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that reacts quickly with NO to produce NO2. It can prevent hypotension and endotoxic shock by directly scavenging NO in a lipopolysaccharide-stimulated rat model.
- Potent nitric oxide (NO) scavenger.
- Reacts quickly with NO to produce NO2.
- Can prevent hypotension and endotoxic shock through direct NO scavenging.
Medchemexpress LLC MF-DH-300 | 2673403-86-4 | 99.5% | 330.38 | 5 MG
MF-DH-300 is a 15-PGDH inhibitor applicable for research into muscle disorders, such as spinal muscular atrophy (SMA). 15-PGDH (15-Hydroxyprostaglandin dehydrogenase) acts as a tumor suppressor, and its decreased expression is linked to increased tumorigenesis. This inhibitor metabolizes intracellular PGE2, preventing it from binding to EP receptors and thereby suppressing PGE2 signaling.
- Can be used for research on muscle disorders
- Inhibits 15-PGDH enzyme
- Suppresses PGE2 signaling
- High purity of 99.53%
- Solid appearance
Medchemexpress LLC Tetrahydro-2H-pyran-2-one-d4 (δ-valerolactone-d4) | 42932-61-6 | 98.6% | 104.14 | 5 MG
Tetrahydro-2H-pyran-2-one-d4 is the deuterium labeled Tetrahydro-2H-pyran-2-one, which is an endogenous metabolite with antioxidant capacity and a small active molecule that can be used as a drug intermediate. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Endogenous metabolite
- Antioxidant capacity
- Small active molecule
- Can be used as a drug intermediate
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Selleck Chemical LLC MF-094-E1098-5MG
MF-094 a potent and selective USP30 inhibitor (IC50 0 12 M) accelerates diabetic wound healing by inhibiting the NLRP3 inflammasome
Medchemexpress LLC (2R)-octyl-α-hydroxyglutarate | 1391194-67-4 | MFCD30735809 | 99.9% | 260.33 g·mol⁻¹ | C13H24O5 | 100 MG
(2R)-Octyl-α-hydroxyglutarate is a cell-permeable, esterified derivative of D-2-hydroxyglutarate used as a research reagent to investigate the biological effects of 2-HG in cellular systems, including effects on histone methylation, DNA damage, and mitochondrial oxidative processes.
- Cell-permeable analogue of D-2-hydroxyglutarate.
- Used to study histone methylation and epigenetic regulation.
- Reported purity approximately 99.9%.
- Molecular weight 260.33 g·mol⁻¹; chemical formula C13H24O5.
- Provided as an analytical/research standard in small pack sizes suitable for cell-based assays.