Pyrans
Medchemexpress LLC MF-094 | 2241025-68-1 | 99.8% | 535.70 | 50 MG
MF-094 is a potent and selective USP30 inhibitor, effective at an IC50 of 120 nM. This compound has been shown to increase protein ubiquitination and accelerate mitophagy, making it suitable for biochemical research applications. It exhibits high selectivity, with less than 30% inhibitory activity against a panel of 22 other USPs at 10 μM.
- Potent and selective USP30 inhibitor
- Increases protein ubiquitination
- Accelerates mitophagy
- Minimal inhibitory activity against other USPs
- Stable as powder at -20°C for 3 years
- Stable in solvent at -80°C for 2 years
eMolecules 38041-19-9 | Tetrahydro-2H-pyran-4-amine | ChemScene | MFCD02179436 | 101.149 | C5H11NO | 98.000 | NC1CCOCC1 | 25g | 536831801
Tetrahydro-2H-pyran-4-amine | ChemScene | 38041-19-9 | MFCD02179436 | 101.149 | C5H11NO | 98.000 | NC1CCOCC1 | 25g | 536831801
Medchemexpress LLC 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)- | 80434-82-8 | 98.5% | 366.45 | 25 UG
20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4. It binds to the BLT1 receptor with high affinity and inhibits LTB4-mediated neutrophil responses, including migration, degranulation, and leukotriene biosynthesis.
- Binds to the BLT1 receptor with high affinity.
- Inhibits LTB4-mediated neutrophil responses.
- It is a human endogenous metabolite.
- Data sheet, COA, SDS, and handling instructions are available.
Medchemexpress LLC Carboxy pyridostatin trifluoroacetate salt | 2444713-88-4 | 99.5% | 820.73 | 100 MG
Carboxy pyridostatin trifluoroacetate salt is a G-quadruplex ligand with high molecular specificity to RNA on DNA G4s, and it also reduces ATF-5 protein. This compound is known to decrease cell proliferation and inhibit stress granule (SG) formation. It is intended for research use only.
- Reduces the size of adult SVZ-derived neurospheres and the number of cells in neurospheres.
- Blocks proliferation and neurosphere fusion in adult SVZ-derived neurosphere cultures.
- Hinders stress granule (SG) formation in U2OS cells.
- Significantly reduces the number of PCNA-expressing cells in the adult SVZ.
- Increases the number of OLIG2-expressing cells in the corpus callosum in C57BL/6 mice.
- Affects the differentiation of neural stem and progenitor cells in different brain regions.
Medchemexpress LLC MF-094 | 2241025-68-1 | 99.8% | 535.70 | 1 ML
MF-094 is a potent and selective inhibitor of USP30 with an IC50 of 120 nM. This compound has been shown to increase protein ubiquitination and accelerate mitophagy.
- Potent and selective USP30 inhibitor
- IC50 of 120 nM for USP30
- Increases protein ubiquitination
- Accelerates mitophagy
- Has <30% inhibitory activity for a panel of 22 USPs assays at 10 uM
eMolecules 40191-32-0 | Tetrahydro-2H-pyran-4-carbonyl chloride | Combi-Blocks | MFCD06200863 | 148.590 | C6H9ClO2 | 97.000 | ClC(=O)C1CCOCC1 | 25g | 335347135
Tetrahydro-2H-pyran-4-carbonyl chloride | Combi-Blocks | 40191-32-0 | MFCD06200863 | 148.590 | C6H9ClO2 | 97.000 | ClC(=O)C1CCOCC1 | 25g | 335347135
eMolecules 287944-16-5 | (3,6-DIHYDRO-2H-PYRAN-4-YL)BORONIC ACID PINACOL ESTER | AstaTech | MFCD11052631 | 210.080 | C11H19BO3 | 95.000 | CC1(C)OB(OC1(C)C)C1=CCOCC1 | 1g | 213339124
(3,6-DIHYDRO-2H-PYRAN-4-YL)BORONIC ACID PINACOL ESTER | AstaTech | 287944-16-5 | MFCD11052631 | 210.080 | C11H19BO3 | 95.000 | CC1(C)OB(OC1(C)C)C1=CCOCC1 | 1g | 213339124
eMolecules 50675-18-8 | Tetrahydropyran-4-carbaldehyde | Chem-Impex | MFCD03425264 | 114.144 | C6H10O2 | 95.000 | O=CC1CCOCC1 | 25g | 205001322
Tetrahydropyran-4-carbaldehyde | Chem-Impex | 50675-18-8 | MFCD03425264 | 114.144 | C6H10O2 | 95.000 | O=CC1CCOCC1 | 25g | 205001322
eMolecules 50675-18-8 | Tetrahydro-2H-pyran-4-carboxaldehyde | Apollo Scientific US | MFCD03425264 | 114.144 | C6H10O2 | 90.000 | O=CC1CCOCC1 | 1g | 591809467
Tetrahydro-2H-pyran-4-carboxaldehyde | Apollo Scientific US | 50675-18-8 | MFCD03425264 | 114.144 | C6H10O2 | 90.000 | O=CC1CCOCC1 | 1g | 591809467
Medchemexpress LLC Tetrahydro-4H-pyran-4-one | 29943-42-8 | 100.0% | C5H8O2 | 10 MM 1 ML
Tetrahydro-4H-pyran-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, the synthesis of symmetric tetra substituted methanes, and is a useful protecting agent for alcohols in nucleotide synthesis.
- Used in preparation of 4-methoxytetrahydropyran-4-yl protecting group.
- Useful protecting agent for alcohols in nucleotide synthesis.
- Employed in studies of enantioselective alpha-aminoxylation of ketones.
- Undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones.
- Utilized in Wittig reactions for the synthesis of penicillins and in a ring of vitamin D3.
eMolecules Tetrahydropyran-4-yl-carboxylic acid | Combi-BlocksMFCD00031016 | 130.143 | C6H10O3 | 97.000 | OC(=O)C1CCOCC1 | 25g | 117518383
Tetrahydropyran-4-yl-carboxylic acid | Combi-BlocksMFCD00031016 | 130.143 | C6H10O3 | 97.000 | OC(=O)C1CCOCC1 | 25g | 117518383
