Pyrazines
TARGETMOL CHEMICALS INC NAVTEMADLIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Navtemadlin (AMG232) is a potent selective and orally available inhibitor of p53-MDM2 interaction (IC50 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM. purity: 98%
TARGETMOL CHEMICALS INC GPR35 AGONIST 2 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the (beta)-arrestin and Ca2+ release assays were 26 and 3.2 nM respectively. purity: 98%
TARGETMOL CHEMICALS INC NOTOGINSENOSIDE FC 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. 1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect. purity: 99%
eMolecules 5780-66-5 | Pyrazine-2-carbaldehyde | Chem-Impex | MFCD02179278 | 108.100 | C5H4N2O | 97.000 | O=Cc1cnccn1 | 1g | 112750982
Pyrazine-2-carbaldehyde | Chem-Impex | 5780-66-5 | MFCD02179278 | 108.100 | C5H4N2O | 97.000 | O=Cc1cnccn1 | 1g | 112750982
TARGETMOL CHEMICALS INC ICFSP1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases. purity: 99%
TARGETMOL CHEMICALS INC ANTITUMOR AGENT-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer. purity: 99%
TARGETMOL CHEMICALS INC EHOP-016 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 uM for Rac1 in MDA-MB-231 and MDA-MB-435 cells equally effective inhibition for Rac3. purity: 99%
TARGETMOL CHEMICALS INC N8-ACETYLSPERMIDINE DIHY 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. N8-Acetylspermidine dihydrochloride is a polyamine that regulates ischemic cardiac apoptosis and resultant cardiac dysfunction. purity: 99%
TARGETMOL CHEMICALS INC ADHP 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ADHP (10-Acetyl-37-dihydroxyphenoxazine) is a fluorogenic peroxidase substrate ((lambda)ex=530 nm (lambda)em=590 nm). purity: 98%
TARGETMOL CHEMICALS INC GNF-5 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50 0.22±0.1 uM Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties. purity: 99%
TARGETMOL CHEMICALS INC MMRI62 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MMRi62 (7-[(23-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol) a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53 also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutation characteristics of KRAS and TP53.12. purity: 99%
Medchemexpress LLC Poly(methyl methacrylate) | 9011-14-7 | (C5H8O2)n | 500 G
Poly(methyl methacrylate) (PMMA) is an amorphous, transparent thermoplastic polymer supplied as solid beads for laboratory and research use. It is commonly used in microfluidic device fabrication, prototyping, and applications that require optical clarity and dimensional stability. The material is provided with supporting documentation for safe handling and analysis.
- Amorphous thermoplastic with high optical clarity.
- Available as solid beads for easy handling and dosing.
- Suitable for microfluidic chip fabrication and prototyping.
- Resistant to many common solvents and chemicals.
- Compatible with molding, machining, and lithographic processing.
- Documentation available: data sheet, SDS, and COA.
eMolecules 27398-39-6 | 3-Chloropyrazine-2-carboxylic acid | Ambeed | MFCD01318438 | 158.540 | C5H3ClN2O2 | 95.000 | OC(=O)c1nccnc1Cl | 250mg | 552661093
3-Chloropyrazine-2-carboxylic acid | Ambeed | 27398-39-6 | MFCD01318438 | 158.540 | C5H3ClN2O2 | 95.000 | OC(=O)c1nccnc1Cl | 250mg | 552661093
TARGETMOL CHEMICALS INC RAF709 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf respectively. purity: 99%
TARGETMOL CHEMICALS INC 6H05 5MG
Also available in 10mg 25mg 50mg and bulk. Please contact Fisher for quotes. 6H05 (K-Ras inhibitor) is a selective allosteric inhibitor of oncogenic mutant K-Ras(G12C). purity: 98%