Pyrazines
TARGETMOL CHEMICALS INC ELOVL1-IN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ELOVL1-IN-2 a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 uM) and demonstrates moderate potency in a primary cellular assay conducted on HEK293 C26 cells (with an IC50 of 6.7 uM) [1]. purity: 99%
TARGETMOL CHEMICALS INC ALOX15-IN-2 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA) the immediate homologs of ALOX15 with IC50s of 1.55 and 2.79 uM respectively. purity: 99%
TARGETMOL CHEMICALS INC CILOMILAST 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM has anti-inflammatory activity and low central nervous system activity. Phase 3. purity: 99%
TARGETMOL CHEMICALS INC VP-4604 50MG
Also available in 100 mg 500 mg and bulk. Please contact Fisher for quotes. VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 ug/mL. VP-4604 inhibited the growth of methicillin-resistant S. aureus with a growth inhibition rate of over 95%. purity: 99%
TARGETMOL CHEMICALS INC ARN25068 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ARN25068 is a potent inhibitor of GSK-3(beta) FYN and DYRK1A protein kinases exerting its activity in the sub-micromolar range. This compound effectively addresses tau hyperphosphorylation [1]. purity: 99%
TARGETMOL CHEMICALS INC YO-01027 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YO-01027 (DBZ) is a potent (gamma)-secretase inhibitor. purity: 99%
TARGETMOL CHEMICALS INC DPTIP 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM. purity: 98%
TARGETMOL CHEMICALS INC SESAMODIL 5MG
Also available in 50 mg 100 mg and bulk. Please contact Fisher for quotes. Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension. purity: 99%
TARGETMOL CHEMICALS INC XU1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. XU1（Benzo[c][18]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition regulation or modulation of kinase signaling. purity: 99%
TARGETMOL CHEMICALS INC SI-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM) but not affect normal cell viability. purity: 98%
TARGETMOL CHEMICALS INC LOFENDAZAM 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Lofendazam (Bu 1014) is a benzodiazepine derivative that has sedative and anxiolytic effects. purity: 98%
TARGETMOL CHEMICALS INC CCT129202 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A Aurora B and Aurora C with IC50 of 0.042 uM 0.198 uM and 0.227 uM respectively. It is less potent to FGFR3 GSK3(beta) PDGFR(beta) etc. purity: 98%