Pyrazines
TARGETMOL CHEMICALS INC JAK-IN-10 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders. purity: 98%
TARGETMOL CHEMICALS INC NRX-103095 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NRX-103095 is a potent enhancer of the interaction of (beta)-catenin with the homologous E3 ligase SCF(beta)-TrCP and enhances the affinity of pSer33/Ser37 (beta)-catenin for (beta)-TrCP with an EC50 of 163 nM. purity: 99%
TARGETMOL CHEMICALS INC CY5.5 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye for labeling biomolecules such as peptides proteins and oligonucleotides (Ex=673 nm Em=707 nm)purity: 96%
TARGETMOL CHEMICALS INC VARESPLADIB 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Varespladib (LY315920) a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM) has been investigated for the treatment and prevention of sickle cell disease vaso-occlusive crisis and acute coronary syndrome. purity: 100%
TARGETMOL CHEMICALS INC VICENIN 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 uM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of (alpha)-glucosidase PTP1B and RLAR. Vicenin 2 has hepatoprotective anti-cancer antioxidant and anti-inflammatory activities and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin 2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin 2 could act as a UV light barrier to protect the plants. purity: 99%
TARGETMOL CHEMICALS INC LIQUIRITIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids and possesses anti-inflammatory and anti-cancer abilities. purity: 98%
TARGETMOL CHEMICALS INC TNIK-IN-5 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. TNIK-IN-5 is an potent TNIK inhibitor (IC50= 0.05 uM). TNIK-IN-5 potently inhibits Wnt signaling in intact cells. TNIK-IN-5 exhibits excellent in vitro anti-colorectal cancer activity. purity: 99%
TARGETMOL CHEMICALS INC N-OXALYLGLYCINE 500MG
Also available in 50 mg 100 mg 200 mg and bulk. Please contact Fisher for quotes. N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of (alpha)-ketoglutarate-dependent enzymes. purity: 98%
TARGETMOL CHEMICALS INC SP-13786 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SP-13786 (UAMC-1110) is an inhibitor of fibroblast activation protein (FAP) (IC50 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 1.8 uM). purity: 99%
TARGETMOL CHEMICALS INC DROXINOSTAT 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Droxinostat (NS 41080) is a selective inhibitor of HDAC mostly for HDACs 6 and 8 with IC50 of 2.47 uM and 1.46 uM greater than 8-fold selective against HDAC3 and no inhibition to HDAC1 2 4 5 7 9 and 10. purity: 99%
TARGETMOL CHEMICALS INC DALBAVANCIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dalbavancin (BI-397) a novel second-generation lipoglycopeptide antibiotic possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE)Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 ug/mL and 0.25 ug/mL respectivelypurity: 98%
TARGETMOL CHEMICALS INC OLOROFIM 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp Dermatophilus spp and Fusarium spp. purity: 98%
TARGETMOL CHEMICALS INC PYOLUTEORIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pyoluteorin is an antibiotic that inhibits Oomycete fungi including the plant pathogen Pythium ultimum and suppresses plant diseases caused by this fungus. Pyoluteorin induces human triple-negative breast cancer MDA-MB-231 cells apoptosis in vitro. purity: 100%
TARGETMOL CHEMICALS INC CPI-0610 CARBOXYLIC ACID 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. CPI-0610 carboxylic acid is an effective and selective small molecule inhibitor of bromine domain and outer end (BET) protein as a ligand of PROTAC target protein. CPI-0610 carboxylic acid may have anticancer and anticancer activities. purity: 98%