Pyrazines
TARGETMOL CHEMICALS INC SC-26196 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 uM in a rat liver microsomal assay with antiinflammatory properties. purity: 99%
Cell Signaling Technology Phospho-Stat6 Tyr641 Matched
Phospho-Stat6 (Tyr641) Matched Antibody Pair 1 Kit
Cell Signaling Technology Total RIP3 Matched Antibody Pair 1 Kit
Total RIP3 Matched Antibody Pair 1 Kit
Cell Signaling Technology Phospho-Stat1 (Tyr701) Matched Antibody Pair 1 Kit
Phospho-Stat1 (Tyr701) Matched Antibody Pair 1 Kit
Cell Signaling Technology Total Neurogranin Matched Antibody Pair 1 Kit
Total Neurogranin Matched Antibody Pair 1 Kit
Cell Signaling Technology Total alpha-Tubulin Matched Antibody Pair 1 Kit
Total alpha-Tubulin Matched Antibody Pair 1 Kit
Cell Signaling Technology Total beta-Catenin Matched Antibody Pair 1 Kit
Total beta-Catenin Matched Antibody Pair 1 Kit
Cell Signaling Technology Phospho-Stat5 (Tyr694) Matched Antibody Pair 1 Kit
Phospho-Stat5 (Tyr694) Matched Antibody Pair 1 Kit
TARGETMOL CHEMICALS INC OAC2 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts; an analog of OAC1. purity: 99%
TARGETMOL CHEMICALS INC AOH1996 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen) targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins leading to DNA replication stress and apoptosis.AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II.AOH1996 acts synergistically with DNA damaging agents to inhibit tumor cell growth. AOH1996 inhibits tumor cell growth by stabilizing the interaction between PCNA and RNA polymerase II leading to proteasome-dependent rpb1 degradation and lethal DNA damage.AOH1996 acts synergistically with DNA damaging agents. purity: 98%
TARGETMOL CHEMICALS INC DS08210767 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. DS08210767 is a highly potent orally bioavailable PTHR1 antagonist with IC50 of 90 nM. purity: 98%
TARGETMOL CHEMICALS INC MIDOSTAURIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha) vascular endothelial growth factor receptor 2 (VEGFR2) c-kit platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases which may result in disruption of the cell cycle inhibition of proliferation apoptosis and inhibition of angiogenesis in susceptible tumors. purity: 99%
TARGETMOL CHEMICALS INC EDO-S101 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9 9 and 25 nM for HDAC1 HDAC2 and HDAC3 respectively. purity: 98%