Pyrazines
TARGETMOL CHEMICALS INC TRANS-TRANILAST 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma allergic rhinitis and atopic dermatitis. purity: 99%
![eMolecules Broadpharm Tri-(Propargyl-PEG2-ethoxymethyl)-methane-amido-PEG3-carboxylate 100mg 603111831 BP-25656 98.000 [null] 945.070 C44H72N4O18](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695492.jpg-250.jpg)
eMolecules Broadpharm Tri-(Propargyl-PEG2-ethoxymethyl)-methane-amido-PEG3-carboxylate 100mg 603111831 BP-25656 98.000 [null] 945.070 C44H72N4O18
Broadpharm Tri-(Propargyl-PEG2-ethoxymethyl)-methane-amido-PEG3-carboxylate 100mg 603111831 BP-25656 98.000 [null] 945.070 C44H72N4O18
eMolecules Combi-Blocks Fmoc-lys(trt)-oh 1g 517031743 QB-5913 98.000 111061-54-2 MFCD00270545 610.754 C40H38N2O4
Combi-Blocks Fmoc-lys(trt)-oh 1g 517031743 QB-5913 98.000 111061-54-2 MFCD00270545 610.754 C40H38N2O4
TARGETMOL CHEMICALS INC NVP-2 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB CDK2/CycA and CDK16/CycY kinases (IC50 0.584 uM 0.706 uM and 0.605 uM respectively). purity: 99%
TARGETMOL CHEMICALS INC CB2R/FAAHMODULATOR-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor the Ki values are 10.8 and 152.9 nM for CB2R and CB1R respectively and the IC50 value for FAAH is 6.2 uM. CB2R/FAAH modulator-2 has studies research value related to cancer deleterious inflammatory cascades occurring in neurodegenerative diseases and COVID-19 infection. purity: 99%
TARGETMOL CHEMICALS INC MBM-55 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. purity: 99%
TARGETMOL CHEMICALS INC GCN2IB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GCN2iB is an ATP-competitive inhibitor of general control nonderepressible 2 (GCN2) with an IC50 of 2.4 nM. purity: 98%
eMolecules ChemScene (E)-4-(Dimethylamino)-2-butenoic acid hydrochloride 5g 844791382 CS-D1794 848133-35-7 MFCD03695466 165.620 C6H12ClNO2
ChemScene (E)-4-(Dimethylamino)-2-butenoic acid hydrochloride 5g 844791382 CS-D1794 848133-35-7 MFCD03695466 165.620 C6H12ClNO2
TARGETMOL CHEMICALS INC VOXTALISIB 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Voxtalisib (XL765) (SAR245409 XL765) is a dual inhibitor of mTOR/PI3K mostly for p110(gamma) with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2. purity: 99%
![eMolecules AstaTech (S)-4-(TERT-BUTOXYCARBONYL)-4-AZASPIRO[2.4]HEPTANE-5-CARBOXYLIC ACID 1g 624136151 89492 95.000 1984825-25-3 MFCD30470755 241.287 C12H19NO4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695468.jpg-250.jpg)
eMolecules AstaTech (S)-4-(TERT-BUTOXYCARBONYL)-4-AZASPIRO[2.4]HEPTANE-5-CARBOXYLIC ACID 1g 624136151 89492 95.000 1984825-25-3 MFCD30470755 241.287 C12H19NO4
AstaTech (S)-4-(TERT-BUTOXYCARBONYL)-4-AZASPIRO[2.4]HEPTANE-5-CARBOXYLIC ACID 1g 624136151 89492 95.000 1984825-25-3 MFCD30470755 241.287 C12H19NO4
TARGETMOL CHEMICALS INC TALNIFLUMATE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. purity: 99%
TARGETMOL CHEMICALS INC DSS30 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl) which reduces the secretion of (beta)-amyloid (A(beta)).DSS30 can be used for the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease. purity: 99%
TARGETMOL CHEMICALS INC FIRATEGRAST 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Firategrast (SB 683699) is an orally active and specific (alpha)4(beta)1/(alpha)4(beta)7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity.Firategrast is used in relapsing-remitting multiple sclerosis.Firategrast treatment is associated with a median cerebrospinal fluid associated with modest reductions in CD4 CD8 and CD19 lymphocyte counts. purity: 99%
Cell Signaling Technology Phospho-Zap-70 (Tyr319) Matched Antibody Pair 1 Kit
Phospho-Zap-70 (Tyr319) Matched Antibody Pair 1 Kit
![eMolecules Synthonix - Stock 2-Cyano-3-cyclopropylacrylic acid 1g 505084659 C45821 98895-60-4 [null] 137.138 C7H7NO2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697259.jpg-250.jpg)
eMolecules Synthonix - Stock 2-Cyano-3-cyclopropylacrylic acid 1g 505084659 C45821 98895-60-4 [null] 137.138 C7H7NO2
Synthonix - Stock 2-Cyano-3-cyclopropylacrylic acid 1g 505084659 C45821 98895-60-4 [null] 137.138 C7H7NO2