Pyrazines
Apexbio Technology LLC 2'-O-Methyl-UTP(Synonyms: 2'-OMe-UTP, 2'-O-Methyluridine-5'-triphosphate, 2'-Methoxyuridine-5'-triphosphate), 10ul (100 mM).
2 -O-Methyl-UTP is a chemically modified analog of uridine triphosphate (UTP) in which the 2 -hydroxyl group of the ribose sugar is replaced by a methyl group This structural alteration confers enhanced resistance to nuclease degradation thereby improving the stability of RNA molecules Due to its heightened stability 2 -O-Methyl-UTP is frequently incorporated into RNA oligonucleotides for RNA interference (RNAi) antisense oligonucleotide research and mRNA modification studies Its application extends broadly to investigations involving gene expression regulation RNA therapeutic designs and nucleic acid delivery platforms in molecular biology and biomedicine
Medchemexpress LLC NPS 2390 | 226878-01-9 | 99.9% | 307.39 | 1 ML
NPS 2390 is a noncompetitive antagonist of mGluR1 and mGluR5. It is also identified as a potent inhibitor of CaSR (calcium-sensing receptor). This product is intended for research use only and is not sold to patients.
- Noncompetitive antagonist of mGluR1 and mGluR5.
- Potent CaSR (calcium-sensing receptor) inhibitor.
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg, 100 mg solid; 10 mM * 1 mL in DMSO solution).
- High purity: 99.90%.
Medchemexpress LLC Butyl isobutyl phthalate | 17851-53-5 | 1 ML
Butyl isobutyl phthalate is a chemical compound isolated from the rhizoid of Laminaria japonica. It acts as a non-competitive α-glucosidase inhibitor with an IC₅₀ value of 38 μM. This compound has demonstrated a hypoglycemic effect, indicating its potential for use in diabetes treatment research.
- Isolated from the rhizoid of Laminaria japonica.
- Functions as a non-competitive α-glucosidase inhibitor.
- Exhibits a hypoglycemic effect.
- Shows potential for diabetes treatment.
- Has an IC₅₀ value of 38 μM against α-glucosidase.
- Molecular formula is C₁₆H₂₂O₄.
- Molecular weight is 278.34.
- Targets glucosidase.
- Purity of 99.31%.
- Appearance is a colorless to light yellow liquid.
TARGETMOL CHEMICALS INC LXH254 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LXH254 is a potent C-Raf and B-Raf inhibitor. purity: 99%
TARGETMOL CHEMICALS INC LIPOFERMATA 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Lipofermata is a fatty acid transport protein (FATP) inhibitor that prevents lipid transport to melanoma cells and reduces melanoma growth and invasion. purity: 99%
Medchemexpress LLC Oenothein B | 104987-36-2 | 5 MG
Oenothein B is a dimeric macrocyclic ellagitannin with broad pharmacological activities, including antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. It is also a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase.
- Dimeric macrocyclic ellagitannin
- Possesses antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties
- Potent and specific inhibitor of poly(ADP-ribose) glycohydrolase
- Inhibits proliferation of A549 cells by inducing apoptosis and arresting cells at G1 stage
- Increases intracellular reactive oxygen species (ROS) and upregulates intracellular apoptotic triggers
- Suppresses lipopolysaccharide (LPS)-induced neuroinflammation in mouse brain
TARGETMOL CHEMICALS INC ECABAPIDE 5MG
Also available in 1mg 10mg 25mg 50mg and bulk. Please contact Fisher for quotes. Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells. purity: 99%
TARGETMOL CHEMICALS INC NEODIOSMIN 100MG
Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Neodiosmin (Diosmetin-7-O-neohesperidoside) has poor aqueous solubility but exerts a good debittering effect and is a strong antioxidant with potential applications in foods beverages and pharmaceutical preparations. purity: 99%
TARGETMOL CHEMICALS INC A 419259 TRIHYDROCHLORID 5MG
Also available in 1mg 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM 3 nM and 3 nM for Src Lck and Lyn). purity: 99%
TARGETMOL CHEMICALS INC FORSYTHOSIDE B 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Forsythoside B binds to LPS and reduces the biological activity of serum LPS and inhibits NF-(kappa)B activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effects with a favorable therapeutic time-window reduce of cerebral ischemia and reperfusion injury degree attenuating blood-brain barrier (BBB) breakdown; Rescued cardiac function from I/R injury. Forsythoside B has antisepsis effect is mediated by decreasing local and systemic levels of a wide spectrum of inflammatory mediators. purity: 98%
TARGETMOL CHEMICALS INC KAEMPFERITRIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes macrophages PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include cell cycle arrest in G1 phase and apoptosis via the intrinsic pathway in a caspase-dependent pathway. purity: 99%
TARGETMOL CHEMICALS INC ELIGLUSTAT 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease. purity: 99%
TARGETMOL CHEMICALS INC VICENIN 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 uM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of (alpha)-glucosidase PTP1B and RLAR. Vicenin 2 has hepatoprotective anti-cancer antioxidant and anti-inflammatory activities and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin 2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin 2 could act as a UV light barrier to protect the plants. purity: 99%