Pyrazines
TARGETMOL CHEMICALS INC REVERSINE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Reversine a small synthetic purine analogue (2 6-disubstituted purine) is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM). purity: 99%
TARGETMOL CHEMICALS INC SR9009 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SR9009 (Stenabolic) a REV-ERB agonist increases the constitutive repression of genes regulated by REV-ERB(alpha)/ERB(beta) (IC50 670/800 nM). Through activation of REV-ERB SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern of core clock genes in the hypothalami of mice. The circadian pattern of expression of an array of metabolic genes in the liver skeletal muscle and adipose tissue was also altered in mice exposed to SR9009 resulting in increased energy expenditure. In Diet-induced obese mice SR9009 (100 mg/kg i.p. b.i.d. for 30 days) could decrease fat mass and markedly improve dyslipidemia and hyperglycemia. purity: 99%
Medchemexpress LLC 5,6-Diamino-1,10-phenanthroline | 168646-54-6 | 210.23 | 1 G
5,6-Diamino-1,10-phenanthroline is a compound that can be used as ligands for metal ions for drug synthesis. It is intended for research use only.
- Can be used as ligands for metal ions
- Suitable for drug synthesis
- For research use only
Cambridge Isotope Laboratories DL-2-Hydroxyestrone-3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
DL-2-Hydroxyestrone-3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
TARGETMOL CHEMICALS INC JT010 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM). purity: 98%
TARGETMOL CHEMICALS INC RELDESEMTIV 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Reldesemtiv (CK-2127107) is a selective activator of fast skeletal muscle troponin with an EC50 of 3.4 uM. Reldesemtiv increases exercise performance in the heart failure model. purity: 95%
![eMolecules 4042-36-8 | D-Pyr-OH | Ambeed | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 25g | 552609317](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695783.jpg-250.jpg)
eMolecules 4042-36-8 | D-Pyr-OH | Ambeed | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 25g | 552609317
D-Pyr-OH | Ambeed | 4042-36-8 | MFCD00066212 | 129.115 | C5H7NO3 | 98.000 | OC(=O)[C@H]1CCC(=O)N1 | 25g | 552609317
TARGETMOL CHEMICALS INC ENDOSIDIN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Endosidin-2 is an exocyst inhibitor a cell-permeable benzylidene benzoylhydrazine that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 uM EXO70A1).Endosidin-2 disrupts protein translocation between the endosomes and plasma membrane thereby facilitating translocation of proteins to the vesicle for degradation. It also inhibits recirculation of endocytosed transferrin to the plasma membrane in HeLa cells and targets multiple isoforms of mammalian EXO70 leading to dysregulation of exocytosis.Endosidin2 can be used as a tool molecule to study cytosolization. purity: 98%
TARGETMOL CHEMICALS INC CB2 RECEPTOR AGONIST 2 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. CB2 receptor agonist 2 (ZINC72105556) is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2. purity: 98%
TARGETMOL CHEMICALS INC TAO KINASE INHIBITOR 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM. purity: 98%
TARGETMOL CHEMICALS INC CDC801 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CDC801 is an inhibitor of PDE4 and TNF-(alpha) with IC50s of 1.1 uM and 2.5 uM respectively. purity: 98%
TARGETMOL CHEMICALS INC KHK-IN-2 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KHK-IN-2 is a selective inhibitor of ketohexokinase with an IC50 value of 0.45 uM. purity: 98%
TARGETMOL CHEMICALS INC TNIK-IN-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK IC50 = 1.33 uM)) which is a downstream signal protein of the Wnt/(beta)-catenin pathway. purity: 98%
TARGETMOL CHEMICALS INC PYRINTEGRIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pyrintegrin is an (beta)1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signaling. purity: 97%
TARGETMOL CHEMICALS INC GW 441756 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM. purity: 99%