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Pyrazines

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eMolecules​ PYRAZINE-2-BORONIC ACID PINACOL ESTER | AstaTech | 1083179-99-0 | MFCD07367532 | 206.050 | C10H15BN2O2 | 95.000 | CC1(C)OB(OC1(C)C)c1cnccn1 | 0.25g | 508840325

PYRAZINE-2-BORONIC ACID PINACOL ESTER | AstaTech | 1083179-99-0 | MFCD07367532 | 206.050 | C10H15BN2O2 | 95.000 | CC1(C)OB(OC1(C)C)c1cnccn1 | 0.25g | 508840325

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2

Cayman Chemical Bortezomib Inhibitors

A dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM); drives cell cycle arrest and apoptosis in cancer cell lines and has applications in multiple myeloma and certain lymphomas, as well as other types of cancer

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3

TARGETMOL CHEMICALS INC IXAZOMIB 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ixazomib (MLN2238) a second generation boron-containing peptide proteasome inhibitor (PI) inhibits the chymotrypsin-like proteolytic ((beta)5) site of the 20S proteasome (IC50/Ki 3.4/0.93 nM in cell-free assays) also inhibits the caspase-like ((beta)1) and trypsin-like ((beta)2) proteolytic sites (IC50 31/3500 nM). purity: 98%

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