Pyrazines
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TARGETMOL CHEMICALS INC CIL56 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated monounsaturated and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1) the rate-limiting enzyme in fatty acid synthesis exhibit 5-fold resistance to CIL56 treatment indicating ACC1 activity sensitizes cells to CIL56-induced cell death. purity: 99%
