Pyridines and derivatives
Apexbio Technology LLC Auranofin(Synonyms: Ridaura, SKF-39162, Gold Sodium Thiomalate, Triethylphosphine gold(I) tetraacetylthioglucose), 50mg, CAS: 34031-32-8.
Auranofin (CAS 34031-32-8) is a small molecule inhibitor targeting thioredoxin reductase (TrxR) a flavoenzyme responsible for channeling electrons from NADPH to thioredoxin crucial in various physiological processes including apoptosis and oxidative stress response Auranofin inhibits TrxR with an IC50 of approximately 88 nM In assays against Helicobacter pylori this inhibitor suppressed bacterial growth at concentrations around 1 2 M Additionally treatment of murine 4T1 and EMT6 tumor cells with Auranofin (3 10 M) enhanced their sensitivity to radiation treatment underscoring its potential for biomedical research in oncology and antimicrobial studies
Apexbio Technology LLC Auranofin(Synonyms: Ridaura, SKF-39162, Gold Sodium Thiomalate, Triethylphosphine gold(I) tetraacetylthioglucose), 10mg, CAS: 34031-32-8.
Auranofin (CAS 34031-32-8) is a small molecule inhibitor targeting thioredoxin reductase (TrxR) a flavoenzyme responsible for channeling electrons from NADPH to thioredoxin crucial in various physiological processes including apoptosis and oxidative stress response Auranofin inhibits TrxR with an IC50 of approximately 88 nM In assays against Helicobacter pylori this inhibitor suppressed bacterial growth at concentrations around 1 2 M Additionally treatment of murine 4T1 and EMT6 tumor cells with Auranofin (3 10 M) enhanced their sensitivity to radiation treatment underscoring its potential for biomedical research in oncology and antimicrobial studies
Medchemexpress LLC Chloro(triphenylphosphine)gold(I) | 14243-64-2 | MFCD00009588 | 99.9% | 494.71 g·mol⁻¹ | C18H15AuClP | 50 MG
Chloro(triphenylphosphine)gold(I) is an organogold reagent (C18H15AuClP) commonly used in organic synthesis and coordination chemistry. It is typically a white to very pale-yellow crystalline powder and serves as a precursor or active species in gold(I)-mediated transformations and research applications.
- High chemical purity suitable for research applications.
- Useful precursor for preparing gold(I) complexes and catalysts.
- Stable crystalline solid at ambient conditions.
- Molecular weight 494.71 g·mol⁻¹; molecular formula C18H15AuClP.
- Well characterized and widely used in synthetic and coordination chemistry.
Medchemexpress LLC Chloro(triphenylphosphine)gold(I) | 14243-64-2 | MFCD00009588 | 99.9% | 494.7 g/mol | C18H15AuClP | 100 MG
Chloro(triphenylphosphine)gold(I) is a gold(I) coordination complex used as a reagent and precursor in organometallic synthesis, homogeneous catalysis, and research applications. It consists of a gold center coordinated by a triphenylphosphine ligand and a chloride ligand.
- Molecular formula C18H15AuClP and molecular weight 494.7 g/mol.
- Commonly supplied as a high-purity crystalline solid for research use.
- Used as a reagent and precursor in organometallic synthesis and homogeneous catalysis.
- Soluble in common organic solvents for solution-phase reactions.
- Classified as an irritant; follow appropriate safety and handling procedures.
Medchemexpress LLC Gold(1+), dichloro(4,4′-dimethoxy-2,2′-bipyridine-κN1,κN1′)-, (SP-4-2)-, hexafluorophosphate(1-) | 1221591-26-9 | 99.0% | 629.07 g/mol | C12H12AuCl2F6N2O2P | 5 MG
AubipyOMe is a gold-containing bipyridine complex used as a biochemical tool to inhibit tartrate-resistant acid phosphatase (TRAP/ACP5). It is supplied as a solid with high purity for research applications, enabling studies of osteoclast and macrophage TRAP activity and related biochemical assays.
- Gold-containing bipyridine complex.
- Potent TRAP/ACP5 inhibitor; IC50 = 1.3 μM (TRAP5a), 1.8 μM (TRAP5b).
- Molecular weight 629.07 g/mol; formula C12H12AuCl2F6N2O2P.
- Purity 99.0% by supplier analysis.
- Solid, off-white to light yellow appearance.
- Supplied in small research quantities, suitable for biochemical assays.
Selleck Chemical LLC Auranofin S4307-25mg
Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H pylori TrxR in cell-free assay Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1 2 M Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis
Selleck Chemical LLC Auranofin S4307-1g
Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H pylori TrxR in cell-free assay Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1 2 M Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis
Medchemexpress LLC 4-Arm PEG-SH MW 500 50mg
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms The reactive free thiol SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver[1]
Selleck Chemical LLC Auranofin S4307-100mg
Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H pylori TrxR in cell-free assay Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1 2 M Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis
Medchemexpress LLC 4-Arm PEG-SH MW 500 25mg
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms The reactive free thiol SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver[1]
Medchemexpress LLC 4-Arm PEG-SH MW 500 100mg
4-Arm PEG-SH (MW 5000) (4-Arm PEG-thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms The reactive free thiol SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver[1]
Medchemexpress LLC 11-mercaptoundecanoic acid | 71310-21-9 | MFCD00022096 | 99.8% | 218.36 g·mol⁻1 | C11H22O2S | 1 G
11-mercaptoundecanoic acid is a thiol-terminated alkyl carboxylic acid commonly used to form self-assembled monolayers (SAMs) on metal surfaces and as a carboxyl-functional linker for surface modification, bioconjugation, and materials research.
- High purity 99.84% as supplied.
- Molecular weight 218.36 g·mol⁻¹, formula C11H22O2S.
- Solid, white to off-white appearance.
- Available in small solid packs and as a DMSO solution for immediate use.
- Powder stability at -20°C for long-term storage; stock solutions stable at -80°C.
- Effective for SAM formation on gold and for carboxyl-based surface coupling.
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