Pyrroles
Medchemexpress LLC TLR7/8 agonist 3 | 642473-95-8 | 100.0% | 50 MG
A potent agonist for TLR7 and TLR8, this compound is derived from patent WO2016057618 (compound of formula (II)) and is intended for research use only. It induces IFN-α and TNF-α in PBMC with EC50 values of 0.12 μM and 0.37 μM, respectively.
- Potent agonist for TLR7 and TLR8.
- Induces IFN-α and TNF-α.
- Suitable for in vitro research applications.
Medchemexpress LLC Entasobulin | 501921-61-5 | 98.5% | 439.89 | 50 MG
Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. It is an indolizine-glyoxylamide based small molecule that demonstrates substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes.
- Inhibits β-tubulin polymerization
- Shows potential anticancer activity
- Demonstrates substantial in vitro anti-proliferative activities against cancer cell lines
- Effective against multidrug resistance (MDR) phenotypes
- For research use only
eMolecules 213743-31-8 | Medchem Express | RK-24466 | 5mg | 437899035 | HY-108318 | MFCD04974490 | 370.456 | C23H22N4O
ChemScene | (S)-2-Amino-5-(isopropylamino)-5-oxopentanoic acid | 250mg | 628857491 | CS-0186170 | 4311-12-0 | MFCD00672360 | 188.227 | C8H16N2O3
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Medchemexpress LLC HY-101971 10mg Medchemexpress, AZ PFKFB3 26 CAS:1704740-52-2 Purity:>98%
Medchemexpress, HY-101971 10mg AZ PFKFB3 26 CAS:1704740-52-2 AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC Heptanoic acid, 7-[[(1,1-dimethylethoxy)carbonyl]amino]- | 60142-89-4 | HY-W012001 | >=98.0% | 245.32 | 100 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000454000-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Heptanoic acid, 7-[[(1,1-dimethylethoxy)carbonyl]amino]- | 60142-89-4 | HY-W012001 | >=98.0% | 245.32 | 100 G
N-Boc-7-aminoheptanoic acid is a PROTAC linker used in the synthesis of PROTACs and other conjugation applications. It features an alkane chain with terminal carboxylic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators like EDC or HATU to form a stable amide bond, and the Boc group can be deprotected under mild acidic conditions to yield the free amine.
- Utilized as a PROTAC linker
- Suitable for PROTAC synthesis
- Suitable for other conjugation applications
- Features an alkane chain with terminal carboxylic acid and Boc-protected amino groups
- Carboxylic acid reacts with primary amines for stable amide bond formation
- Boc group deprotects under mild acidic conditions to yield free amine
Medchemexpress LLC HY-18935A 5mg Medchemexpress, CBL0137 hydrochloride CAS:1197397-89-9 Purity:>98%
Medchemexpress, HY-18935A 5mg CBL0137 hydrochloride CAS:1197397-89-9 CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC50s of 0.37 and 0.47 µM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC JMS-17-2 | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 | C25H26ClN3O | 50MG
JMS-17-2 is a small-molecule research compound that functions as a potent and selective antagonist of the CX3CR1 receptor (IC50 = 0.32 nM). It has been used in preclinical studies to impair metastatic seeding and colonization of breast cancer cells. The material is supplied as a high-purity solid with recommended cold storage for prepared solutions to preserve stability.
- Chemical formula: C25H26ClN3O.
- Molecular weight: 419.95 g·mol-1.
- High purity suitable for research use.
- Appearance: white to off-white solid.
- Storage: store solid at 4°C protected from light; store solutions at -20°C to -80°C for longer-term stability.
- Applications: in vitro and in vivo studies of CX3CR1-mediated processes and metastasis models.
- Available in multiple pack formats including small mg quantities and ready-to-use DMSO solutions.
Selleck Chemical LLC LLY-507-5mg
LLY-507 is a cell-active, potent, and selective inhibitor of protein-lysine Methyltransferase SMYD2.
Medchemexpress LLC HY-119933 10mg Medchemexpress, RIPK1-IN-7 CAS:2300982-44-7 Purity:>98%
Medchemexpress, HY-119933 10mg RIPK1-IN-7 CAS:2300982-44-7 RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-Acetylpyrrole | 1072-83-9 | 99.54% | 109.13 | 250 G
2-Acetylpyrrole is an organic compound featuring a pyrrole ring. It is formed during the Maillard browning reaction and functions as a significant flavor component in various foods. This compound also serves as an intermediate in the synthesis of other active compounds, such as the flavor compound 2-acetyl-1-pyrroline.
- Purity: 99.54%
- Molecular weight: 109.13
- Formula: C6H7NO
- CAS no.: 1072-83-9
- Appearance: Solid
- Color: White to off-white
- Structure classification: Alkaloids, pyrrole alkaloids
- Initial source: Microorganisms, specifically *Streptomyces sp. A-5071*
- Solubility (in vitro): 100 mg/mL in DMSO
Medchemexpress LLC HY-15420 10mg Medchemexpress, BML-190 CAS:2854-32-2 Purity:>98%
Medchemexpress, HY-15420 10mg BML-190 CAS:2854-32-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Acid Red 27
Acid Red 27 (Azorubin S Amaranth) is a modified red azo dye used as a food dye and to color cosmetics
eMolecules 1049741-03-8 | Medchem Express | SPD304 (dihydrochloride) | 5mg | 761953613 | HY-111255A | MFCD09265259 | 620.54 | C32H34Cl2F3N3O2
Medchem Express | Ascr5 | 5mg | 600899991 | HY-N6978 | 1086696-26-5 | 220.221 | C9H16O6
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eMolecules 156161-89-6 | Medchem Express | BQ-788 (sodium salt) | 1mg | 446266888 | HY-15894 | MFCD00797882 | 663.792 | C34H50N5NaO7
ChemScene | 4455-Tetramethyl-2-(4-(3-(trifluoromethyl)phenoxy)phenyl)-132-dioxaborolane | 100mg | 717420824 | CS-0527550 | 2171363-95-2 | MFCD14581940 | 364.170 | C19H20BF3O3
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