Pyrroles
Enzo Life Sciences ET B receptor antagonist. sodium salt (0.5mg). CAS: 156161-89-6
Highly potent and selective ETB-receptor antagonist. Alternative name: BQ-788 . Na. Formula: C34H50N5O7Na. MW: 663.7. Purity: ≥95% (HPLC). Appearance: White to off-white powder. Formulation: Lyophilized from 0.1M sodium bicarbonate. Peptide content: 75-95%. Solubility: Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water. Long Term Storage: -20°C.
Medchemexpress LLC Tlr7/8/9-in-1 | 2180127-82-4 | 98.5% | 435.60 g/mol | C27H37N3O2 | 5 MG
TLR7/8/9-IN-1 is a potent, orally bioavailable small-molecule antagonist of Toll-like receptors 7, 8, and 9 used in preclinical studies to inhibit TLR signaling and downstream cytokine release. The compound is supplied as a high-purity solid with published in vitro and in vivo solubility and activity data.
- Potent antagonist activity (IC50 = 43 nM in TLR7/8/9 assays)
- Demonstrates 4.8 nM potency versus TLR7 in PBMC IL-6 reduction
- High reported purity of 98.5%
- Molecular weight 435.60 g/mol; formula C27H37N3O2
- Solid, off-white to light-yellow physical appearance
- Soluble in DMSO (83.33 mg/mL) and formulated for in vivo use (≥2.08 mg/mL)
- Suitable for preclinical studies of TLR pathway modulation
Medchemexpress LLC HY-109020 5mg Medchemexpress, Acrizanib CAS:1229453-99-9 Purity:>98%
Medchemexpress, HY-109020 5mg Acrizanib CAS:1229453-99-9 Acrizanib is a VEGFR-2 inhibitor, with an IC 50 of 17.4 nM for BaF3-KDR. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1415390-47-4 | Medchem Express | (R)-BPO-27 | 1mg | 446270328 | HY-19778 | MFCD30532675 | 548.349 | C26H18BrN3O6
Ambeed | 5-Nitroquinoxaline | 250mg | 525227737 | A599476 | 18514-76-6 | MFCD01684951 | 175.147 | C8H5N3O2
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Medchemexpress LLC TRILACICLIB HYDROCHLORIDE 10MG
Trilaciclib hydrochloride (Synonyms: G1T28 hydrochloride) 10mgCAS #1977495-97-8
eMolecules 1421783-64-3 | Medchem Express | Olverembatinib (dimesylate) | 5mg | 533802555 | HY-15666A | MFCD26142656 | 724.77 | C31H35F3N6O7S2
Ambeed | 13-Bis((S)-1-(naphthalen-1-yl)ethyl)-1H-imidazol-3-ium chloride | 100mg | 633660903 | A1473472 | 188840-13-3 | 412.960 | C27H25ClN2
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eMolecules 1892576-58-7 | Medchem Express | PF-06747711 | 5mg | 459606849 | HY-112706 | 497.522 | C26H26F3N5O2
Medchem Express | Aloesin | 1mg | 495800908 | HY-N2460 | 30861-27-9 | MFCD00869744 | 394.376 | C19H22O9
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Medchemexpress LLC HY-112706 5mg Medchemexpress, PF-06747711 CAS:1892576-58-7 Purity:>98%
Medchemexpress, HY-112706 5mg PF-06747711 CAS:1892576-58-7 PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 ( RORC2 , also known as RORγt ) inverse agonist, with an IC 50 of 4.1 nM. Anti-skin inflammatory activity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC S-Indoximod (1-Methyl-L-tryptophan) | 21339-55-9 | 218.25 | 100 MG
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) with a Ki of 19 μM. It can be utilized for research related to cancer and neurological disease.
- Inhibitor of indoleamine 2,3-dioxygenase (IDO).
- Can be used for the research of cancer.
- Can be used for the research of neurological disease.
- Reduces IDO activity in HEK293 cells.
- Promotes the apoptosis of hepatic stellate cells.
- Reverses Bacillus Calmette-Guerin (BCG)-induced neurotoxicity in mice.
- Shows renoprotective effect in the IRI rat model.
- Reverses cognitive, anxiety, and depressive-like behavior in bile duct ligation (BDL) rats.