Pyrroles
Medchemexpress LLC (-)-Corey lactone diol | 32233-40-2 | 172.18 | 5 G
(-)-Corey lactone diol is the reduced form of Corey aldehyde. It is used as a drug intermediate for the synthesis of Beraprost.
- Drug intermediate
- Chiral building block
- Used in the synthesis of prostaglandin analogue Beraprost
- Relevant for inflammation or immune system disease research
- Relevant for blood or cardio-cerebrovascular disease research
Selleck Chemical LLC Vicriviroc Malate S2004-5mg
Vicriviroc is a potent CCR5 antagonist with IC50 of 0 91 nM showing broad-spectrum activity against genetically diverse HIV-1 isolates and also drug-resistant viruses with RTI PRI or MDR phenotypes Phase 3
Medchemexpress LLC STING agonist-3 trihydrochloride | 98.4% | 860.19 g/mol | C37H45Cl3N12O6 | 1 ML
STING agonist-3 trihydrochloride is a selective, non-nucleotide small-molecule stimulator of interferon genes (STING) supplied as a 10 mM solution in DMSO for research use. The compound is provided as the trihydrochloride salt with reported purity of 98.36% and molecular weight 860.19 g/mol; storage recommendations are solid at 4°C protected from light and under nitrogen, and in solvent at -80°C (up to 6 months) or -20°C (up to 1 month).
- Selective non-nucleotide STING agonist with pEC50 of 7.5.
- Supplied as a 10 mM solution in DMSO, 1 mL vial.
- Trihydrochloride salt form to aid handling and solubility.
- High purity (98.36%) with supporting analytical data.
- Intended for immuno-oncology and STING pathway research.
- Documentation available: datasheet, COA, SDS, HNMR, LCMS.
Selleck Chemical LLC Pizotifen Malate S1394-50mg
Pizotifen Malate (Sandomigran pizotyline BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches
Cayman Chemical NdecanoylLHomoserine lactone
A small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and affecting cellular metabolism; applications for this molecule include regulation of virulence and exoproteases
Medchemexpress LLC Sunitinib impurity 28 | 1186651-51-3 | 98.5% | 299.31 | 25 MG
Sunitinib impurity 28 is an impurity of Sunitinib. It is for research use only and not sold to patients. The appearance is a solid.
- Impurity of Sunitinib
- Appearance is a solid
- For research use only
Selleck Chemical LLC Sunitinib malate S1042-1g
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR with IC50 of 80 nM and 2 nM in cell-free assays and also inhibits c-Kit Sunitinib Malate effectively inhibits autophosphorylation of Ire1 Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-5mg
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)
Medchemexpress LLC Atorvastatin sodium | 134523-01-6 | MFCD08458204 | 99.9% | 580.6 g/mol | C33H34FN2NaO5 | 1 ML
Atorvastatin sodium is the sodium salt of atorvastatin, an HMG-CoA reductase inhibitor used in research on lipid metabolism, cardiovascular biology, and inflammation. It is supplied at high purity and is available as solids and as a 10 mM solution in DMSO for biochemical and cell-based assays.
- High purity suitable for research (≈99.9%).
- Available as 10 mM DMSO solution for ready-to-use dosing.
- Also available as multiple solid weights for formulation or storage.
- Used in assays targeting HMG-CoA reductase and related pathways.
- Documented activity in cellular and in vivo cardiovascular models.
Medchemexpress LLC Pitavastatin lactone | 141750-63-2 | 99.3% | 403.45 g/mol | C25H22FNO3 | 10MG
Pitavastatin lactone is the lactone metabolite of pitavastatin and is supplied as a research-grade reference compound for metabolite identification, analytical method development, and pharmacokinetic studies. The material is provided as a high-purity solid with specified storage recommendations for stability.
- High purity: 99.3%.
- Molecular weight: 403.45 g/mol.
- Chemical formula: C25H22FNO3.
- Appearance: white to off-white solid.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Common applications: metabolite standard, LC-MS method validation, pharmacokinetic studies.
Selleck Chemical LLC Atorvastatin Calcium S2077-500mg
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol Atorvastatin Calcium induces apoptosis and autophagy
Cayman Chemical NheptanoylLHomoserine lactone
A small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and affecting cellular metabolism; applications of this molecule include regulation of virulence, infection prevention, and septicemia in fish
Apexbio Technology LLC Almotriptan Malate 181183-52-8 100mg
Almotriptan Malate (CAS 181183-52-8) is a small molecule belonging to the triptan class acting as a selective agonist at 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptors By stimulating these receptors Almotriptan modulates cranial vasoconstriction and inhibits the release of pro-inflammatory neuropeptides biologically counteracting migraine pathophysiology In research applications Almotriptan Malate is utilized to investigate serotonergic signaling pathways migraine mechanisms and the pharmacodynamics of 5-HT1B/1D receptor modulation in neurological models
Medchemexpress LLC N-Desethyl Sunitinib | 356068-97-8 | 99.9% | 370.42 | 100 MG
N-Desethyl Sunitinib (SU-12662) is a metabolite of Sunitinib. It serves as a good transport substrate for human ABCB1, ABCG2, and murine ABCG2. It is for research use only.
- Good transport substrate for human ABCB1, ABCG2, and murine ABCG2.
- Effective against K562 cells.
- Provided as a solid.