Pyrroles
Medchemexpress LLC Varespladib methyl | 172733-08-3 | 99.9% | 394.42 | 100 MG
Varespladib methyl is a selective inhibitor of group II secretory phospholipase A2 (PLA2). It is an orally-administered methyl ester pro-drug that is metabolized to LY315920.
- Selective inhibitor of group II secretory phospholipase A2 (PLA2)
- Orally-administered methyl ester pro-drug
- High-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations
- White to off-white solid appearance
- Intended for research use only
Aobchem 1-Methylpyrrole-2-carboxaldoxime | 95% | CAS 55970-42-8 | C6H8N2O | 250mg
1-Methylpyrrole-2-carboxaldoxime | 95% | CAS 55970-42-8 | C6H8N2O | 250mg
Medchemexpress LLC HY-114530 10mg Medchemexpress, LY2452473 CAS:1029692-15-6 Purity:>98%
Medchemexpress, HY-114530 10mg LY2452473 CAS:1029692-15-6 LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Varespladib methyl | 172733-08-3 | 99.9% | 394.42 | 5 MG
Varespladib methyl is a selective inhibitor of group II secretory phospholipase A2 (PLA2). This orally-administered methyl ester pro-drug is metabolized to LY315920 and shows high-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations against 28 medically important snake venoms.
- Selective inhibitor of group II secretory phospholipase A2 (PLA2)
- Orally-administered methyl ester pro-drug
- Metabolized to LY315920
- Shows high-level secretory PLA2 (sPLA2) inhibition
- Effective against 28 medically important snake venoms
Medchemexpress LLC AZ7550 Mesylate | 2319837-99-3 | 98.7% | 5 MG
AZ7550 Mesylate is an active metabolite of AZD9291 and acts as an inhibitor of IGF1R with an IC50 of 1.6 μM. This compound exhibits a potency and selectivity profile similar to its parent compound, AZD9291, making it suitable for various research applications.
- Inhibits IGF1R with an IC50 of 1.6 μM
- Active metabolite of AZD9291
- Exhibits similar potency and selectivity profile to AZD9291
- Inhibits double mutant cell line H1975 with IC50 of 45 nM
- Inhibits activating mutant cell line PC9 with IC50 of 26 nM
- Inhibits wild type cell line LoVo with IC50 of 786 nM
- For research use only
Medchemexpress LLC 2-Acetylpyrrole | 1072-83-9 | 99.5% | 109.13 | 10 G
2-Acetylpyrrole is an organic compound featuring a pyrrole ring. It is a natural product of the Maillard browning reaction and is recognized as a significant flavor component in various foods. This compound also functions as an intermediate in the synthesis of other active compounds, such as the flavor compound 2-acetyl-1-pyrroline. For in vitro applications, 2-Acetylpyrrole reacts with nitrite to produce 1-nitro-2-acetylpyrrole (NAP) and 1,3,5-trinitro-2-acetylpyrrole (TNAP), which have demonstrated moderate mutagenicity and strong cytotoxicity.
- Organic compound with a pyrrole ring
- Product of Maillard browning reaction
- Major flavor component in many foods
- Intermediate in synthesis of other active compounds
- Suitable for research and analytical applications
- Reacts with nitrite to form nitropyrrole compounds
Medchemexpress LLC 2-Acetylpyrrole | 1072-83-9 | 99.98% | 109.13 | 25 G
2-Acetylpyrrole is an organic compound containing a pyrrole ring. It is a product of the Maillard browning reaction and acts as a major flavor component in many foods. It can also be used as an intermediate in the synthesis of other active compounds, such as 2-acetyl-1-pyrroline. This product is for research use only.
- Organic compound with a pyrrole ring
- Product of Maillard browning reaction
- Major flavor component in many foods
- Intermediate in synthesis of other active compounds
- Solid, white to off-white appearance
Medchemexpress LLC HY-N2128 5mg Medchemexpress, Nigakinone CAS:18110-86-6 Purity:>98%
Medchemexpress, HY-N2128 5mg Nigakinone CAS:18110-86-6 Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-119933 5mg Medchemexpress, RIPK1-IN-7 CAS:2300982-44-7 Purity:>98%
Medchemexpress, HY-119933 5mg RIPK1-IN-7 CAS:2300982-44-7 RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a K d of 4 nM and an enzymatic IC 50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-Morpholinecarboxamide, N-[4-[[5-(1,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-4-yl)-... | 2205095-75-4 | 99.9% | 532.68 g/mol | C29H40N8O2 | 5 MG
TLR7/8-IN-1 is a crystalline form of a dual TLR7/TLR8 inhibitor (patent WO2019220390, compound 2b) provided for laboratory research, including studies of autoimmune disease. The compound is supplied as a white to off-white solid or as DMSO solutions, and is characterized by defined molecular and purity data for reproducible preclinical use.
- High purity: 99.92%.
- Molecular weight: 532.68 g/mol.
- Chemical formula: C29H40N8O2.
- Soluble in DMSO (12.5 mg/mL; ultrasonic recommended).
- Available as milligram quantities or 10 mM DMSO solutions for experimental use.
- Storage stability: powder -20 °C (3 years); in solvent -80 °C (6 months).
Medchemexpress LLC HY-15772A 10mg Medchemexpress, Osimertinib mesylate CAS:1421373-66-1 Purity:>98%
Medchemexpress, HY-15772A 10mg Osimertinib mesylate CAS:1421373-66-1 Osimertinib mesylate (AZD-9291 mesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Az PFKFB3 26 | 1704740-52-2 | MFCD30742931 | 98.3% | 402.49 | C24H26N4O2 | 25 MG
AZ PFKFB3 26 is a potent, selective small-molecule inhibitor of PFKFB3 used in research on glycolytic regulation and cancer metabolism. It displays low-nanomolar biochemical potency and measurable cellular effects in tumor cell assays, and is provided as a high-purity solid for laboratory use.
- Potent PFKFB3 biochemical inhibitor (IC50 23 nM).
- Selective over PFKFB1 and PFKFB2 (IC50s 2.06 μM and 0.384 μM).
- Active in A549 cells (fructose-1,6-bisphosphate reduction IC50 0.343 μM).
- High-purity research-grade material suitable for in vitro studies.
- Available in small pack sizes for preclinical experiments.