Pyrroles
Apexbio Technology LLC Almotriptan Malate 181183-52-8 100mg
Almotriptan Malate (CAS 181183-52-8) is a small molecule belonging to the triptan class acting as a selective agonist at 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptors By stimulating these receptors Almotriptan modulates cranial vasoconstriction and inhibits the release of pro-inflammatory neuropeptides biologically counteracting migraine pathophysiology In research applications Almotriptan Malate is utilized to investigate serotonergic signaling pathways migraine mechanisms and the pharmacodynamics of 5-HT1B/1D receptor modulation in neurological models
TARGETMOL CHEMICALS INC Atorvastatin lactone 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Purity 98.16%
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-25mg
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)
Medchemexpress LLC HY-13781 500mg Medchemexpress, Pemetrexed (disodium hemipenta hydrate) Pemetrexed sodium hydrate CAS:357166-30-4 Purity:98%
Medchemexpress,HY-13781 500mg Pemetrexed (disodium hemipenta hydrate) Pemetrexed sodium hydrate CAS:357166-30-4 Formula:C20H21N5O6 . 5/2 H2O . 2Na Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Pizotifen Malate 5189-11-7 500mg
Pizotifen malate (CAS 5189-11-7) is a benzocycloheptane derivative that functions as a potent antagonist of serotonin (5-HT) receptors exhibiting high selectivity for this target class By inhibiting serotonergic neurotransmission Pizotifen malate is utilized in biomedical research to investigate the physiological and pharmacological roles of 5-HT pathways Its receptor blocking properties enable studies focused on serotonergic modulation migraine mechanisms and disorders associated with altered serotonin signaling
TARGETMOL CHEMICALS INC Sacubitril hemicalcium salt
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug of LBQ657, which is an inhibitor of the zinc metallopeptidase neprilysin. Neprilysin degrades a variety of vasoactive peptides such as atrial and brain natriuretic peptide, bradykinin, adrenomedullin, and endothelin-1. Inhibition of neprilysin leads to an increased level of these peptides and, thus, antihypertensive effects. Formulations containing AHU377 in combination with the angiotensin II receptor antagonist valsartan are used to treat hypertension and heart failure. Purity 99.93%
Apexbio Technology LLC Bromoenol lactone 88070-98-8 25mg
Bromoenol lactone (CAS 88070-98-8) is an irreversible inhibitor of cytosolic calcium-independent phospholipase A2 (iPLA2) an enzyme involved in the regulation of arachidonic acid release and lysophospholipid production iPLA2 activity is associated with phospholipid remodeling and the generation of signaling molecules that modulate processes such as eicosanoid synthesis insulin secretion apoptosis and cellular proliferation In cellular assays bromoenol lactone induces apoptosis in various cell lines and promotes proteolysis of procaspase-9 and procaspase-3 It also inhibits phosphatidic acid phosphohydrolase activity and disrupts triacylglycerol biosynthesis in macrophage models Bromoenol lactone is widely utilized in studies investigating lipid signaling cell death mechanisms and metabolic pathways
Medchemexpress LLC Pipemidic acid trihydrate | 72571-82-5 | 98.0% | 357.36 | 100 MG
Pipemidic acid trihydrate is a derivative of Piromidic acid and functions as an antibacterial agent. It inhibits DNA gyrase. This compound is effective against gram-negative bacteria, including Pseudomonas aeruginosa, and also some gram-positive bacteria. It is suitable for research concerning intestinal, urinary, and biliary tract infections.
- Inhibits DNA gyrase
- Active against gram-negative bacteria, including Pseudomonas aeruginosa
- Active against some gram-positive bacteria
- Can be used for research of intestinal, urinary, and biliary tract infections
Medchemexpress LLC HY-19903 5mg Medchemexpress, ASP-9521 CAS:1126084-37-4 Purity:>98%
Medchemexpress, HY-19903 5mg ASP-9521 CAS:1126084-37-4 ASP-9521 is a potent, selective and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, hydrate (2:1:3), (βR,δR)- | 344423-98-9 | 99.8% | 605.71 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436307-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, hydrate (2:1:3), (βR,δR)- | 344423-98-9 | 99.8% | 605.71 | 1 ML
Atorvastatin calcium salt trihydrate is a statin-class drug used to lower blood cholesterol levels. It is effective in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme responsible for cholesterol production in the liver. This product also serves as a biochemical reagent for life science research.
- Controls high levels of LDL cholesterol and triglycerides.
- Reduces the risk of heart attack and stroke.
- Inhibits HMG-CoA reductase.
- Useful as a biochemical reagent for life science research.
AdipoGen L-Homoserine lactone HCl
Chemical. CAS 2185-03-7. Formula C4H7NO2 . HCl. MW 137.56. L-Homoserine lactone is a synthetic building block or intermediate used in the synthesis of organoselenium chemistry intermediates and analogs of bacterial quorum-sensing signaling molecules.