Pyrroles
Medchemexpress LLC Bromoenol lactone | 88070-98-8 | MFCD00270871 | ≥98.0% | 317.18 g/mol | C16H13BrO2 | 1 ML
Bromoenol lactone is an irreversible, suicide-type inhibitor of calcium-independent phospholipase A2 (iPLA2β). It is provided as a concentrated solution (commonly 10 mM in DMSO) for biochemical and cell-based research, with a reported IC50 of approximately 7 μM.
- Irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2β).
- Reported IC50 of approximately 7 μM.
- Supplied as a 10 mM solution in DMSO for laboratory use.
- High purity: ≥98.0% (TLC).
- Chemical formula C16H13BrO2, molecular weight 317.18 g/mol.
- For research use only; not for human therapeutic use.
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | 449.47 | 50 MG
Atorvastatin epoxy tetrahydrofuran impurity is an impurity isolated from the oxidative degradation products of atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor that effectively decreases blood lipids. This product is for research use only and not sold to patients.
- Isolated from oxidative degradation products of atorvastatin.
- Atorvastatin is an orally active HMG-CoA reductase inhibitor.
- Effectively decreases blood lipids.
- Reduces apoptosis of myocardial cells by down-regulating GRP78, caspase-12, and CHOP expression after myocardial infarction.
- Involved in activation of endoplasmic reticulum (ER) stress in response to heart failure and angiotensin II (Ang II) stimulation.
Medchemexpress LLC Pravastatin lactone | 85956-22-5 | 99.2% | 5 MG
Pravastatin lactone is the delta-lactone metabolite of pravastatin and a potent inhibitor of HMG-CoA reductase. It is used as a research reagent to study statin metabolism and cholesterol biosynthesis in biochemical and pharmacological assays.
- Potent HMG-CoA reductase inhibitor used in cholesterol synthesis studies.
- High purity suitable for analytical and biochemical applications.
- Available in small milligram quantities for assay development and metabolism studies.
- Molecular formula C23H34O6 and molecular weight 406.51 g/mol aid identification and dosing.
- Provided as a neat solid for laboratory research use.
Selleck Chemical LLC Almotriptan Malate S2096-10mg
Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist used for the treatment of Migraine attacks in adults
Medchemexpress LLC Bromoenol lactone | 88070-98-8 | MFCD00270871 | ≥98.0% | 317.18 g/mol | C16H13BrO2 | 10 MG
Bromoenol lactone is a suicide-based, irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2β) used in biochemical research. It inhibits iPLA2β with an IC50 of approximately 7 μM and has been reported to block antigen-stimulated mast cell exocytosis without affecting Ca2+ influx. The compound is supplied as a solid for laboratory preparation of stock solutions.
- Irreversible mechanism-based inhibitor of iPLA2β.
- Reported IC50 of approximately 7 μM.
- Useful for studying phospholipase A2-mediated signaling and mast cell exocytosis.
- Available as a solid suitable for solution preparation.
- Molecular weight 317.18 g/mol; molecular formula C16H13BrO2.
Cayman Chemical 4-hydroxy Atorvastatin calci
A metabolite of atorvastatin; formed by metabolism of atorvastatin by CYP3A4
Medchemexpress LLC Atorvastatin ethyl ester | 1146977-93-6 | MFCD28143549 | 98.2% | 586.69 g/mol | C35H39FN2O5 | 5 MG
Atorvastatin ethyl ester is a research chemical derivative of atorvastatin reported to strongly inhibit 9-cis-retinoic acid (9-cis-RA)-induced Gal4 reporter activity. It is intended for preclinical research use and is characterized by CAS 1146977-93-6, molecular formula C35H39FN2O5, and molecular weight 586.69 g/mol.
- Reported inhibitor of 9-cis-RA-induced Gal4 reporter activity.
- Intended for research use only, not for human consumption.
- High purity (98.2%).
- Characterized by CAS 1146977-93-6 and formula C35H39FN2O5.
- Available in small pack sizes suitable for assay development, including five mg packs.
Medchemexpress LLC HY-112898 10mg Medchemexpress, DC1SMe CAS:501666-85-9 Purity:>98%
Medchemexpress, HY-112898 10mg DC1SMe CAS:501666-85-9 DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.